An interventional study of Physical exercise and cognitive exercises in Acute Hospitalization, sponsored by Universidad Pública de Navarra. Not yet recruiting. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2025-09-19.
Sponsored by Universidad Pública de Navarra · Not applicable, Interventional, and Treatment
This research project is structured in two phases: an initial observational phase and a subsequent randomized controlled trial (RCT) phase. The goal of the observational phase is to compare hospital admission and Hospital at Home (HaH). The objective of the RCT is to assess the effectiveness of a multicomponent intervention following acute hospitalization in older adults. The main questions it aims to answer are:
Researchers will compare a post-discharge multicomponent intervention to usual care to see the effects on physical and cognitive function.
Participants will receive a home-based cognitive and physical exercise intervention or usual care.
2,426 studies on the registry are indexed under Motor Activity; 1,161 are open to participants now.
This study's planned enrollment of 200 is above the median of 60 across 2,118 interventional studies indexed under Motor Activity.
Browse Motor Activity studies →Universidad Pública de Navarra is the lead sponsor of 13 studies on the registry; 4 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Physical exercise and cognitive exercises
Behavioral: Physical exercise and cognitive exercises
The intervention will be based on the Vivifrail program, which is a multicomponent physical exercise program designed specifically for older adults.
Physical function
Short Physical Performance Battery (SPPB): scores range from 0 to 12, with higher scores indicating better physicalfunction.
Time frame: Within the first 24-48 hours of acute care admission (in hospital or home hospitalization), pre-intervention baseline, and immediately after the intervention.
Cognitive function
Mini-Mental State Examination (MMSE): scores range from 0 to 30, with higher scores indicating better cognitive function.
Time frame: Within the first 24-48 hours of acute care admission (in hospital or home hospitalization), pre-intervention baseline, and immediately after the intervention.
Physical activity
Physical activity will be assessed with a Firstbeat device (format: hh:mm:ss).
Time frame: During hospital stay or during home-base hospitalization .
Sedentarism
Sedentarism will be assessed with a Firstbeat device (format: hh:mm:ss).
Time frame: During hospital stay or during home-based hospitalization.
Health-related quality of life (HRQOL)
EQ-5D-5L provides a health profile that is converted to a utility index, in which 0 is equivalent to death and 1 indicates perfect health. Additionally, the EQ-VAS ranges from 0 to 100, with higher scores indicating better health.
Time frame: Pre-intervention baseline and immediately after the intervention.
Heart rate variability
Heart rate variability will be assessed usign a Firstbeat device.
Time frame: During hospital stay or during home-based hospitalization.
Handgrip strength
Handgrip strength will be measured using a handgrip dynamometer.
Time frame: Within the first 24-48 hours of acute care admission (in hospital or home hospitalization), pre-intervention baseline, and immediately after the intervention.
Sleep quantity
Sleep duration will be recorded (format: hh:mm:ss).
Time frame: During hospital stay or during home-based hospitalization.
Sleep quality
The heart rate variability parameter RMSSD (measured in ms) will be assessed during sleep.
Time frame: During hospital stay or during home-based hospitalization.
Energy expenditure
Energy expenditure (kcal) will be assessed in with a Firstbeat device.
Time frame: Within the first 24-48 hours of acute care admission (in hospital or home hospitalization), pre-intervention baseline, and immediately after the intervention.
Rate of hospital readmissions
Number of readmissions of each patient will be registered using the information from the medical records.
Time frame: 3 months, 6 months, and 12 months post-discharge.
Rate of falls
The number of falls for each patient will be recorded through follow-up phone calls.
Time frame: 3 months, 6 months, and 12 months post-discharge.
Incidence of mortality
Number of deaths will be registered using the information from the medical records.
Time frame: 3 months, 6 months, and 12 months post-discharge.
Rate of emergency visits
Number of emergency visits will be registered using the information from the medical records.
Time frame: 3 moths, 6 months, and 12 months post-discharge.
Prescribed pharmacologic treatment
All medications prescribed to each patient will be recorded using the information from the medical records.
Time frame: Within the first 24-48 hours of acute care admission (in hospital or home hospitalization), pre-intervention baseline, and immediately after the intervention.
Cost-effectiveness
Cost-effectiveness will be assessed by calculating the cost per Quality-Adjusted Life Year (QALY) gained.
Time frame: At pre-intervention baseline, at 3 months post-discharge, at 6 months post-discharge, and at 12 months post-discharge.
No study locations are listed for this record.
Plan to share: Undecided
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Jun 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Universidad Pública de Navarra