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Enrolling by invitationNCT07159698Updated Nov 24, 2025

Clinical Profile of a Patient After MI and ACVA Based on Outpatient Register Data

An observational study in Acute Cerebrovascular Accident and Myocardial Infarction (MI), sponsored by State Institution "Republican Scientific and Practical Center" Cardiology, Belarus. Enrolling by invitation at 1 site in Belarus. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-11-24.

Sponsored by State Institution "Republican Scientific and Practical Center" Cardiology, Belarus · Observational

Study type
Observational
Model
Case-control
Time perspective
Other
Enrollment
1,520
Ages
18 Years and older
Sex
All
01

Study summary

This is a retrospective observational study using the methodology of creating medical registries. The expected number of patients included in the registry is about 2000 patients with myocardial infarction and/or ACVD of any duration and concomitant non-cardiac diseases of therapeutic profile in pilot healthcare organizations for any reason during 2019-2022 based on the source medical records data.

Read the detailed description

Abstract The article presents the results of the analysis of outpatient register data of patients after myocardial infarction (MI) and acute cerebrovascular accident (ACVA). Based on the epidemiological characteristics of individuals included in the register, a clinical "portrait of a patient" after an acute cardiovascular event was formed. The features of clinical and laboratory parameters, as well as behavioral and metabolic factors of cardiovascular risk in patients included in the study were determined; and adherence to treatment before and after the reference event was assessed over a 12-year follow-up period.

The objective of the study: to determine the features of clinical and epidemiological characteristics and parameters of laboratory and instrumental studies, the profile of cardiovascular risk factors in patients with a history of MI and ACVA, and to establish their adherence to treatment before and after the reference event over a 12-year follow-up period.

Materials and methods. The investigators analyzed the data of 410 patients who applied to an outpatient and polyclinic healthcare organization between January 1, 2019, and December 31, 2022, with confirmed acute (recurrent) myocardial infarction and/or cerebral infarction that occurred between January 1, 2010, and December 31, 2019. Patients were included in the register after establishing their vital status as of January 1, 2020. The data of records and reports from healthcare organizations (forms 025/u, 131-u) and electronic outpatient records of medical information systems (MIS) from outpatient polyclinic institutions (OPI) were used. The results of the retrospective stage analysis of the study and the electronic patient database from the information and analytical system "Register of MI/ACVA" were presented. Standard methods of descriptive and analytical statistics, statistical software packages (SPSS, SAS, STATISTIKA 10, Stata) and programming languages (R, Python) were used.

02

Conditions studied

  • Acute Cerebrovascular Accident
  • Myocardial Infarction (MI)

Keywords

  • register
  • myocardial infarction
  • acute cerebrovascular accident
  • quality of medical care
  • outpatient and polyclinic institutions
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All patients who applied to the outpatient clinic for any reason between 2019-2022 in order to identify and "look for" patients after acute cardiovascular event and myocardial infarction, meeting the inclusion criteria.

Inclusion criteria

  • history of MI and/or ACVA of any remoteness;
  • visit to the outpatient clinic for any reason during the period from January 1, 2019, to December 31, 2022;
  • age 18 years or older;
  • the presence of informed consent for the processing of personal data in the outpatient medical record;
  • permanent residence in the city where the register is being established.

Exclusion criteria

Exclusion Criteria:

  • non-compliance with the inclusion criteria.
04

Study design

Observational model
Case-control
Time perspective
Other
Enrollment
1,520 participants (estimated)
Target follow-up
3 Years
Patient registry
Yes

Groups and cohorts

  • myocardial infarction (MI)

    Patients with a history of MI of any remoteness; visit to the outpatient clinic for any reason during the period from January 1, 2019, to December 31, 2022; age 18 years or older; the presence of informed consent for the processing of personal data in the outpatient medical record; and permanent residence in the city where the register is being established.

  • acute cerebrovascular accident (ACVA)

    Patients with a history of ACVA of any remoteness; visit to the outpatient clinic for any reason during the period from January 1, 2019, to December 31, 2022; age 18 years or older; the presence of informed consent for the processing of personal data in the outpatient medical record; and permanent residence in the city where the register is being established.

  • acute cerebrovascular accident + myocardial infarction (ACVA+MI)

    Patients with a history of MI and ACVA of any remoteness; visit to the outpatient clinic for any reason during the period from January 1, 2019, to December 31, 2022; age 18 years or older; the presence of informed consent for the processing of personal data in the outpatient medical record; and permanent residence in the city where the register is being established.

05

What researchers measure

Primary outcomes

  1. Identification of the main risk factors for the development of heart attacks and/or strokes in the group of studied patients.

    For this purpose, primary medical documentation and patient's dispensary observation cards were used. Participants achieved target levels of indicators of the main risk factors according to established standards in accordance with international recommendations.

    Time frame: 5 years

06

Study locations

1 site
  • Republican Scientific and Practical Center of Cardiology
    Minsk, 220036, Belarus
07

References and documents

Study documents

  • Study protocol · Sep 30, 2025

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: Undecided — Protection of personal data

08

Registry details

Key details

Study ID
NCT07159698
Lead sponsor
State Institution "Republican Scientific and Practical Center" Cardiology, Belarus
Collaborators
Belarusian State Medical University
Responsible party
Pabivantsava Natallia (Head of the Laboratories of Comorbid Cardiology, RSPC Cardiology, Ph.D (Medicine), State Institution "Republican Scientific and Practical Center" Cardiology, Belarus) — Principal investigator
First posted
Sep 8, 2025
Start date
Jan 1, 2025
Primary completion
Oct 1, 2025
Completion
Jun 1, 2026 (estimated)
Last update
Nov 24, 2025

Study contacts

Elena Grigorenko, Ph.D
study chair · Republican Scientific and Practical Center of Cardiology

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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