An observational study in Small Bowel Obstruction and Small Bowel Obstruction Adhesion, sponsored by The First Affiliated Hospital with Nanjing Medical University. Completed at 1 site in China. Open to participants aged 14 Years and older. Per ClinicalTrials.gov, last updated 2025-09-02.
Sponsored by The First Affiliated Hospital with Nanjing Medical University · Observational
Small bowel obstruction (SBO) is a surgical emergency in which the passage of intestinal contents is prevented due to mechanical obstruction of small intestine. It accounts for almost 50% of all emergency laparotomies with significant in-hospital morbidity and costs. SBO has known to occur in patients who had no prior abdominal surgery, referring to as a virgin abdomen (VA). Nowadays, non-operative management comprising of bowel decompression, water-soluble contrast agents, and fluid resuscitation have been found safe and efficacious in 70% of SBOs caused by adhesions (ASBO). However, based on the assumption that SBO in the virgin abdomen (SBO-VA) is usually caused by other aetiologies than adhesions, such as malignancy and hernias, many authors suggest that surgical exploration is still mandatory. Besides, recent studies do show high incidence of adhesions also in patients with SBO-VA. This observation signifies that guideline on the management of ASBO might also apply to the majority of patients with SBO-VA. Hence, the aim of our retrospectively study is to shed light on the aetiologies of SBO-VA. We believe treatment strategy needs to be based on the underlying reasons of obstructions and conditions of the patients and evaluate their prognosis accordingly.
The First Affiliated Hospital with Nanjing Medical University is the lead sponsor of 543 studies on the registry; 301 are open to participants now.
Counted across the registry records on this site, refreshed daily.
From January 2009 to December 2020, 2098 consecutive patients with 2275 admissions who diagnosed with bowel obstuction were enrolled in the First Affiliated Hospital of Nanjing Medical University, P. R. China. For patients with multiple admissions, only the index admissions were included, the rest were used for follow-up analysis. The detailed medical records of those 2098 patients were collected and reviewed. Only patients without prior abdominal operations and with CT or surgical exploration confirmation of the diagnosis of SBO were included. In addition, patients with age less than 14 years were excluded in this study. The diagnosis of SBO was established if an attending surgeon documented interpretation of CT imaging and was in agreement with the diagnosis. Finally, 312 patients with SBO in virgin abdomen were included in this study.
Exclusion Criteria:
small intestinal obstruction patients without a history of abdominal surgery (virgin abdomen)
The recurrence rate within 5 years after discharge
The recurrence rate of small bowel obstruction within 5 years after discharge
Time frame: 5 years
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
The First Affiliated Hospital with Nanjing Medical University