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CompletedNCT07143994Updated Aug 27, 2025

EFFECT OF ECCENTRIC AND CONCENTRIC EXERCISE PROGRAMS For HAMSTRING GRADE INJURIES

An interventional study of eccentric exercise and concentric exercise in Hamstring Injuries, sponsored by Yeditepe University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-08-27.

Sponsored by Yeditepe University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 7 years 6 months after the study started (first participant enrolled Feb 2018, registered Aug 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Hamstring injuries are common and recurrent in both elite and recreational athletes, often leading to prolonged absence from sports. The aim of this study is to compare the effects of eccentric and concentric exercise programs on the recovery of elite athletes diagnosed with grade II hamstring strain. Pain, flexibility, muscle strength, balance, and return-to-sport duration will be evaluated to determine the impact of different exercise modalities. Dynamic balance assessment will also be performed before and after treatment. The two intervention groups will be compared using the Wilcoxon test, with p\<0.01 considered statistically significant. This study is expected to provide evidence on which exercise program is more effective in facilitating return to sport and to contribute to improved rehabilitation strategies in future athletic injuries.

Read the detailed description

amstring muscle strain is one of the most common injuries in elite sports, frequently leading to long rehabilitation periods and a high rate of recurrence. Although various treatment modalities have been studied, there is still no consensus on the most effective exercise approach for recovery and return to sport. This study investigates the effectiveness of two different rehabilitation strategies-eccentric exercise programs and concentric exercise programs-in elite athletes diagnosed with grade II hamstring strain.

The intervention will focus on structured exercise protocols applied over a defined treatment period. Outcomes to be assessed include pain intensity, hamstring flexibility, isometric and isotonic muscle strength, dynamic balance, and time to return to sport. Dynamic balance assessment is included as a novel parameter to better understand functional recovery after hamstring injury.

Statistical analysis will be performed using the Wilcoxon test for continuous variables, with p\<0.01 considered significant. The results are expected to clarify which type of exercise program provides superior outcomes in terms of functional recovery and safe return to sport. This may help guide clinicians in designing more effective rehabilitation strategies for elite athletes and reduce the recurrence of hamstring injuries.

02

Conditions studied

  • Hamstring Injuries

Keywords

  • grade 2 muscle injury
  • eccentric exercise
  • concantric exercise
  • balance
03

In context

Lead sponsor

Yeditepe University is the lead sponsor of 127 studies on the registry; 31 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Participants over 18 ,who are elite athlete and contunie currently active sports life,and . Those with MRI findings showing hamstring grade II strain,who does not have any systemic or mental disease volunteerly participated in the study.

Exclusion criteria

Exclusion Criteria:

  • Participants who are having severe visual impairment and perception impairment, who has pain preventing to test,who has neurologic problems ans who has a history of injury for 6 months were excluded.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
30 participants (actual)

Study arms

  • Experimental
    Eccentric Exercise Program

    Elite athletes with grade II hamstring strain will undergo a structured rehabilitation protocol consisting of eccentric strengthening exercises. The program is designed to improve hamstring flexibility, strength, dynamic balance, and facilitate safe return to sport.

    Other: eccentric exercise

  • Experimental
    Concentric Exercise Intervention

    Elite athletes with grade II hamstring strain will undergo a structured rehabilitation protocol consisting of concentric strengthening exercises. The program is designed to enhance hamstring flexibility, muscle strength, dynamic balance, and assist in safe return to sport.

    Other: concentric exercise

Interventions

  • Othereccentric exercise

    This study's interventions are distinguished by the specific application of eccentric and concentric exercise programs tailored for elite athletes with grade II hamstring strains.

  • Otherconcentric exercise

    This study's interventions are distinguished by the specific application of eccentric and concentric exercise programs tailored for elite athletes with grade II hamstring strains.

06

What researchers measure

Primary outcomes

  1. Time to Return to Sport

    he duration (in days) from the start of the rehabilitation program until the athlete meets all return-to-play criteria, including complete pain relief, sufficient muscle strength, joint mobility, flexibility, running and gait analysis, physical fitness, balance, dynamic functional performance, lumbopelvic motor control, and subjective readiness reported by the athlete.

    Time frame: From baseline until return to sport, up to 12 weeks

07

Study locations

1 site
  • HANTAL
    Istanbul, Kartal 34755, Turkey (Türkiye)
08

References and documents

Individual participant data

Plan to share: Undecided — A decision regarding the sharing of individual participant data (IPD) has not yet been made. Considerations regarding participant privacy, confidentiality, and the sensitive nature of the data will inform any future decisions on data sharing.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 27, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07143994
Lead sponsor
Yeditepe University
Responsible party
Feyza Sule BADILLI HANTAL (Asst.Prof, Yeditepe University) — Principal investigator
First posted
Aug 27, 2025
Start date
Feb 20, 2018
Primary completion
Jan 1, 2024
Completion
Jun 17, 2024
Last update
Aug 27, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.

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