CClinicalTrials.gg
CompletedNCT07140705Updated Dec 23, 2025

Personalized Virtual Reality for Promoting Well-Being and Psychological Flexibility in General Practitioners

An interventional study of Transformative Virtual Reality Experience and ACT for General Practitioners in Healthy Participants, sponsored by Catholic University of the Sacred Heart. Completed at 1 site in Italy. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-12-23.

Sponsored by Catholic University of the Sacred Heart · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
21
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

General Practitioners (GPs) face significant daily challenges, and promoting their well-being is essential. In particular, psychological flexibility (PF) is a key indicator of well-being. PF, conceptualized within Acceptance and Commitment Therapy (ACT), supports adaptation to change and fosters adaptive responses to demanding and complex situations. ACT identifies six core processes, which can be grouped into two functional units: the mindful acceptance of one's thoughts and emotions (acceptance, cognitive defusion, openness to internal experiences), and the commitment to engaging in actions that enrich one's life (values and committed action).

This project will investigate the feasibility of a transformative metaphorical Virtual Reality (VR) experience to promote psychological flexibility and well-being in GPs. Specifically, this goal will be pursued through the integration of a metaphorical virtual experience, previously validated by the research team for its capacity to foster a transformative experience (TE)-that is, an experience that enables individuals to explore new ways of thinking and contributes to reshaping self-perception-with guided reflection on personal values and support in enacting value-consistent behaviors.

A total of 25 GPs will participate in a single in-person session involving a 10-minute transformative VR experience ("The River and the Leaf"). Drawing on ACT metaphors, participants will be guided to reflect on aspects of the experience, on the professional challenges they face, and on the personal resources available to them. Following this experience, they will be supported in identifying the values that guide their everyday actions. After the in-person session, all participants will be encouraged to identify and implement value-based committed actions over the following two weeks, supported by two audio tracks.

02

Conditions studied

  • Healthy Participants

Keywords

  • Virtual reality
  • Transformative Experience
  • Acceptance and Commitment Therapy
  • General Practitioners
  • Personal values
  • Committed action
  • Psychological flexibility
03

In context

Lead sponsor

Catholic University of the Sacred Heart is the lead sponsor of 227 studies on the registry; 28 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • being a General Practitioner and having an adequate understanding of the Italian language.

Exclusion criteria

Exclusion Criteria:

  • having pre-existing medical conditions that prevent the use of the Meta Quest 3 headset:
  • presence of binocular visual abnormalities;
  • history of seizures or epileptic conditions;
  • presence of cardiac pacemakers, defibrillators, or implanted devices;
  • use of hearing aids.
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
21 participants (actual)

Study arms

  • Experimental
    Experimental group

    Other: Transformative Virtual Reality Experience and ACT for General Practitioners

Interventions

  • OtherTransformative Virtual Reality Experience and ACT for General Practitioners

    This intervention consists of an individual, in-person session in which each participant engages in a 10-minute transformative Virtual Reality (VR) experience entitled "The River and the Leaf", delivered through the Meta Quest 3 headset. Drawing on Acceptance and Commitment Therapy (ACT) metaphors, participants are guided to reflect on key aspects of the experience, their professional challenges, and the personal resources available to them. Following the VR session, participants are supported in clarifying the values that guide their everyday actions. After the in-person session, all participants are encouraged to identify and implement committed actions aligned with their values over the subsequent two weeks, supported by two dedicated audio tracks.

06

What researchers measure

Primary outcomes

  1. The Comprehensive assessment of ACT (CompACT)

    This self-report scale was developed by Francis et al. (2016; Giovannetti et al., 2022) to measure psychological flexibility. The scale consists of 23 items, which can be answered using a 6-point Likert scale, where 0 indicates "completely disagree" and 6 "completely agree." The questionnaire is divided into three subscales: Openness to Experience (OE), Behavioral Awareness (BA), and Valued Action (VA), which correspond to the three pillars of psychological flexibility. Higher scores on the CompACT indicate greater psychological flexibility.

    Time frame: This questionnaire will be administered at T0 (baseline) and at T2 (post-intervention, i.e., two weeks after the individual in-person session).

  2. Mental Health Continuum Short Form (MHC-SF)

    This self-report scale was developed by Keyes (2002; Petrillo et al., 2015) to measure emotional, social, and psychological well-being. The scale consists of 14 items, which can be answered using a 6-point Likert scale, where 0 indicates "never" and 5 "every day." To assess the three dimensions, the questionnaire is divided into three subscales: the Emotional Well-Being scale (EWB, items 1-3), the Social Well-Being scale (SWB, items 4-8), and the Psychological Well-Being scale (PWB, items 9-14). Higher scores on the MHC-SF indicate greater well-being.

    Time frame: This questionnaire will be administered at T0 (baseline) and at T2 (post-intervention, i.e., two weeks after the individual in-person session).

  3. Visual Analogue Scale (VAS) for the assessment of emotions

    This scale aims to measure the intensity of positive and negative emotions (joy, contentment, pride, love, compassion, awe, hope, gratitude, sadness, fear, anger, admiration, inspiration, and awe) (Shiota et al., 2006; Cloos et al., 2023). The intensity can be expressed using a Likert scale, where 0 corresponds to "not at all" and 10 to "very much."

    Time frame: This questionnaire will be administered at T0 (baseline) and at T1 (immediately after the VR experience).

  4. Ad hoc questionnaire to investigate the impact of the VR transformative experience

    This 6-item questionnaire is designed to evaluate the transformative experience, its pleasantness, and its impact on self-expansion. Responses are provided on a 7-point Likert scale, where 1 indicates "not at all" and 7 indicates "very much."

    Time frame: This questionnaire will be administered at T1 (immediately after the VR experience).

Secondary outcomes

  1. Slater Usoh Steed Presence Questionnaire (SUS)

    This self-report scale was developed by Usoh et al. (2000) to assess the user's sense of presence in the virtual environment. The instrument consists of 6 items, which are rated on a 7-point Likert scale. Higher scores on the SUS indicate a greater sense of presence.

    Time frame: This questionnaire will be administered at T1 (immediately after the VR experience).

  2. Valued Living Questionnaire (VLQ)

    This questionnaire is designed to assess valued living and is divided into two sections (Wilson et al., 2002; Miselli et al., 2008). In the first section, participants are asked to rate the importance of 10 life domains on a 10-point Likert scale (where 1 = not at all important and 10 = extremely important). The life domains are: (1) family, (2) marriage/partnership/intimate relationships, (3) parenting, (4) friendship, (5) work, (6) education, (7) recreation, (8) spirituality, (9) citizenship, and (10) self-care. The second section asks participants to rate the extent to which their actions over the past week were consistent with each value/domain. Responses are given on a 10-point Likert scale (where 1 = not at all consistent and 10 = extremely consistent).

    Time frame: This questionnaire will be administered at T1 (after the VR experience) and at T2 (post-intervention, i.e., two weeks after the individual in-person session).

  3. Maslach Burnout Inventory (MBI)

    This questionnaire was developed by Maslach et al. (1997) to measure levels of burnout. It consists of 16 items rated on a 7-point Likert scale, where 0 corresponds to "never" and 6 to "every day." The questionnaire is divided into three subscales: Emotional Exhaustion (EE), Depersonalization (DP), and Reduced Personal Accomplishment (PA), which represent the three core dimensions of burnout.

    Time frame: This questionnaire will be administered at T0 (baseline) and at T2 (post-intervention, i.e., two weeks after the individual in-person session).

07

Study locations

1 site
  • Università Cattolica del Sacro Cuore
    Milan, Milano 20123, Italy
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 23, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07140705
Lead sponsor
Catholic University of the Sacred Heart
Collaborators
Italian Ministry of University and Research (MUR), European Union
Responsible party
Daniela Villani (Associate Professor in General Psychology, Catholic University of the Sacred Heart) — Principal investigator
First posted
Aug 25, 2025
Start date
Sep 1, 2025
Primary completion
Nov 15, 2025
Completion
Nov 30, 2025
Last update
Dec 23, 2025

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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