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CompletedNCT07133282FABULOSUpdated Aug 21, 2025

SingHealth Polyclinics - Functional Strength Building of Older Persons

An interventional study of Group exercise programme in Prefrail Elderly, sponsored by SingHealth Polyclinics. Completed at 4 sites in Singapore. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2025-08-21.

Sponsored by SingHealth Polyclinics · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 3 years 2 months after the study started (first participant enrolled Mar 2022, registered May 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
227
Allocation
Not applicable
Ages
65 Years and older
Sex
All
01

Study summary

The goal of this study is to find out if a 12-week exercise programme for pre-frail seniors will result in an improvement in physical performance measures.

Participants attended 12 group exercise sessions, lasting one hour each, and held once a week. Three of these sessions were be conducted remotely, via a video link that participants will follow at their own time. Physical performance measures were taken at the first and last sessions.

02

Conditions studied

  • Prefrail Elderly
03

In context

Lead sponsor

SingHealth Polyclinics is the lead sponsor of 22 studies on the registry; 5 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • 65 years or older, and
  • Clinical Frailty score of 3 or 4.

Exclusion criteria

Exclusion Criteria:

  • Persons who had pre-existing medical contraindications to exercise OR
  • clinical symptoms that rendered them unsuitable for physical activity as determined by their attending physician OR
  • cognitive impairment affecting their ability to provide informed consent.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
227 participants (actual)

Study arms

  • Experimental
    Exercise group

    The intervention was twelve sessions of group exercise, delivered by exercise physiologists from ProAge (a health promotion social enterprise), lasting one hour each and conducted weekly. Each group had 10-15 participants. Nine sessions were held in-person, and three out of these twelve sessions were held remotely - the physiologist would send a video link of an exercise session for participants to follow at their own time for the week.

    Behavioral: Group exercise programme

Interventions

  • BehavioralGroup exercise programme

    12-week group exercise programme

06

What researchers measure

Primary outcomes

  1. Short physical performance battery score

    It assesses the functional mobility of an older adult's lower extremities in three domains (static balance, gait speed and chair stands). Balance is evaluated via the duration which participant can maintain side-by-side, semi-tandem, and tandem stances. Gait speed is measured by duration taken by the participant to walk 3 meters at their usual pace. Lower limb strength is assessed using the chair stand test, which records the time taken to complete five consecutive sit-to-stand movements from an armless chair with the participants' arms folded across the chest.

    Time frame: Assessed at baseline (at the start of the first exercise session) and 12 weeks (during the 12th exercise session)

  2. Hand grip strength

    It is assessed using a handgrip dynamometer, with participants' elbows flexed at 90 degrees with the forearm in neutral position, squeezing the device as hard as possible with their left and right hands. The average recorded value from two measurements was used for analysis of this study

    Time frame: Assessed at baseline (at the start of the first exercise session) and 12 weeks (during the 12th exercise session)

  3. 30-Seconds Sit-to-Stand repetitions

    30-Seconds Sit-to-Stand repetitions is a measure of lower limb strength, endurance, and functional fitness. It is performed by recording the maximum number of times a participant can stand up fully and sit down from an armless chair within 30 seconds, with their arms folded across their chest. A higher number of repetitions indicate better functional capacity

    Time frame: Assessed at first exercise session and 12th exercise session (i.e. 12 weeks from baseline)

Secondary outcomes

  1. Change in exercise category in the International Physical Activity Questionnaire-Short Form (IPAQ-SF)

    Participants reported their physical activity based on an interviewer-administered IPAQ-SF during the enrolment visit, 6-month and 12-month after the start of the structured exercise programme. The IPAQ-SF is a validated instrument widely used as a measure of physical activity. The questionnaire contains 8 items, which assesses the frequency and duration of physical activity across domains such as sitting, walking, moderate-intensity activities and vigorous intensity activities. Based on the responses, the total metabolic equivalent (MET)-minutes per week is calculated, and participants are categorised into low, moderate, or high physical activity levels. There is no minimum or maximum value of MET-minutes per week as this is based on the participants' responses.

    Time frame: At enrolment, 6months post enrolment and 12 months post enrolment.

Other outcomes

  1. Satisfaction scores

    A researcher-developed satisfaction survey was used to assess participants' satisfaction with the sessions, instructors, venue, pace, exercises, and the perceived effects of FABULOS on their health.

    Time frame: Administered at 12 weeks (i.e. at the 12th session).

07

Study locations

4 sites
  • SingHealth Polyclinics - Marine Parade
    Singapore, Singapore 440080, Singapore
  • SingHealth Polyclinics - Sengkang
    Singapore, Singapore 545025, Singapore
  • SingHealth Polyclinics - Punggol
    Singapore, Singapore 820681, Singapore
  • SingHealth Polyclinics - Tampines
    Singapore, Singapore Singapore, Singapore
08

References and documents

Individual participant data

Plan to share: No — Sharing of IPD outside of the study team was not included in the informed consent form signed earlier by the participants.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 21, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07133282
Lead sponsor
SingHealth Polyclinics
Responsible party
Sponsor
First posted
Aug 21, 2025
Start date
Mar 15, 2022
Primary completion
Jun 8, 2023
Completion
Jan 16, 2024
Last update
Aug 21, 2025

Study contacts

Pei Lin Hu, MBBS, MMED(FM), FCFP(S)
principal investigator · SingHealth Polyclinics

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.

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