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RecruitingNCT07090356Updated Jul 29, 2025

Instrument-Assisted Soft Tissue Mobilization Versus PNF Stretching in Athletes With Piriformis Syndrome

An interventional study of Instrument-Assisted Soft Tissue Mobilization and Proprioceptive Neuromuscular Facilitation Stretching in Piriformis Syndrome, sponsored by Riphah International University. Recruiting at 1 site in Pakistan. Open to participants aged 18 Years to 35 Years. Per ClinicalTrials.gov, last updated 2025-07-29.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jul 2025, 1 year 2 months ago, but the record still lists the study as recruiting.
  • Registered 11 months after the study started (first participant enrolled Jul 2024, registered Jul 2025).
  • Started Jul 2024; still recruiting 2 years 2 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
18 Years to 35 Years
Sex
All
01

Study summary

A 12-month randomized controlled trial will be conducted at Pakistan Sports Board, Lahore, with 40 athletes (18-35 years) randomly allocated to IASTM (n=20) or PNF (n=20) groups. Interventions were administered 3 times/week for 4 weeks. Outcomes included Numeric Pain Rating Scale (NPRS), goniometric hip ROM, and Oswestry Disability Index (ODI).

Read the detailed description

The objective of this study will be to compare the effectiveness of IASTM versus PNF stretching to manage Piriformis Syndrome in a 4 - week randomized controlled trial (RCT). Random allocation was done to the IASTM group or the PNF stretching group. Physiotherapy interventions to reduce pain, increase muscle flexibility and increase functional outcomes will be given to both groups.

Before the intervention, all participants will underween a comprehensive assessment, including:

  • Numeric Pain Rating Scale (NPRS) for pain intensity
  • Oswestry Disability Index (ODI) for functional disability
  • Goniometric measurement for hip joint range of motion (ROM)

Group A: Instrument-Assisted Soft Tissue Mobilization (IASTM) Group

IASTM therapy was provided to participants in whom a specialized instrument was used to apply controlled pressure over the piriformis muscle as well as surrounding soft tissues. The procedure included:

  • Warm-up: Light aerobic exercise (5 minutes)
  • IASTM Application: Applied over the piriformis muscle in a longitudinal and cross-fiber pattern for 5-7 minutes
  • Static stretching of the piriformis and gluteal muscle activation exercises are completed next.
  • Cool-down: Light stretching and relaxation

Group B: Proprioceptive Neuromuscular Facilitation (PNF) Stretching Group

PNF stretching (contract relax; hold relax) was implemented to stretch participants' muscles as flexibly and with as much control as possible. The procedure included:

  • Warm-up: Light aerobic exercise (5 minutes)
  • PNF Stretching:

    • The second technique was based on hold-relax technique during which the participant actively contracted the piriformis muscle against resistance for 5 seconds, followed by a 10 seconds passive stretch.
    • Contract relax technique: same as the above but with deeper stretches following an active contraction
    • Repeated for 3 sets per session
  • Exercises to strengthen the core and hip muscles to provide stability
  • Gentle stretching and deep breathing for cool down

Physiotherapy Management (Common for Both Groups)

In addition, the following was provided to all the participants together with their respective interventions:

  • Ice/heat application as needed (based on the individual).
  • Education \& Ergonomic Advice: Guidance on proper posture, activity modification, and self-care techniques Specific exercises will be assigned to maintain flexibility and strength (Home Exercise Program).
02

Conditions studied

  • Piriformis Syndrome
03

In context

Piriformis Muscle Syndrome

53 studies on the registry are indexed under Piriformis Muscle Syndrome; 22 are open to participants now.

This study's planned enrollment of 40 is close to the median of 42 across 47 interventional studies indexed under Piriformis Muscle Syndrome.

Browse Piriformis Muscle Syndrome studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,133 studies on the registry; 633 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 35 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Professional Athletes aged 18 to 35 years.
  • Chronic pain in the buttock and hip area.
  • Inability to sit for a prolonged time.
  • Athletes having positive Faber test
  • Both male and female athletes
  • Practicing athletes who are in practice from last 2 years.

Exclusion criteria

Exclusion Criteria:

  • Trauma history from last 6 months.
  • Other injuries excluding hip pain.
  • Systemic illness.
  • Pre-existing neurological conditions affecting the lower limbs
  • History of lower back surgery
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
40 participants (estimated)

Study arms

  • Experimental
    Instrument-Assisted Soft Tissue Mobilization

    IASTM therapy will be provided to participants in whom a specialized instrument wwill be used to apply controlled pressure over the piriformis muscle as well as surrounding soft tissues.

    Other: Instrument-Assisted Soft Tissue Mobilization

  • Experimental
    Proprioceptive Neuromuscular Facilitation Stretching

    PNF stretching (contract relax; hold relax) was implemented to stretch participants' muscles as flexibly and with as much control as possible.

    Other: Proprioceptive Neuromuscular Facilitation Stretching

Interventions

  • OtherInstrument-Assisted Soft Tissue Mobilization

    IASTM therapy will be provided to participants in whom a specialized instrument will be used to apply controlled pressure over the piriformis muscle as well as surrounding soft tissues.

  • OtherProprioceptive Neuromuscular Facilitation Stretching

    PNF stretching (contract relax; hold relax) will be implemented to stretch participants' muscles as flexibly and with as much control as possible.

06

What researchers measure

Primary outcomes

  1. Numeric Pain Rating Scale

    Numeric Pain Rating Scale

    Time frame: 6 weeks

  2. Hip ROM

    Goniometry

    Time frame: 6 weeks

  3. Oswestry Disability Index

    Questionaire

    Time frame: 6 weeks

07

Study locations

1 of 1 sites recruiting
  • Pakistan Sports Board
    Lahore, Punjab Province 54000, Pakistan
    • Hafiz Amir · Contact · 04299230383
    • Rukash Mehar, DPT · Principal investigator
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 29, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07090356
Lead sponsor
Riphah International University
Responsible party
Sponsor
First posted
Jul 29, 2025
Start date
Jul 30, 2024
Primary completion
Jul 30, 2025 (estimated)
Completion
Aug 30, 2025 (estimated)
Last update
Jul 29, 2025

Study contacts

Imran Amjad, Phd PT
Contact
imran.amjad@riphah.edu.pk
03324390125
Muhammad Hassan, MSPT
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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