Piriformis Muscle Syndrome clinical trials
The registry lists 58 studies for Piriformis Muscle Syndrome across 8 countries. 22 are recruiting or about to start. 54 of them are mainly about Piriformis Muscle Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13.
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Status
Phase
- Phase 2
- 1
Who runs them
Riphah International University (13) · Istanbul University - Cerrahpasa (5) · Foundation University Islamabad (5) · University of Faisalabad (3) · Ankara City Hospital Bilkent (2) · University of Lahore (2) · Sehat Medical Complex (2) · Diskapi Teaching and Research Hospital (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Nov 2026Comparative Effects of Post-Isometric Relaxation and Reciprocal Inhibition Techniques inPiriformis Syndrome · Riphah International University
- Nov 2026Effects of MET and MFR on Piriformis Syndrome · Igdir University
- Jul 2027Interfascial Hydrodissection Added to Ultrasound-Guided Piriformis Injection for Piriformis Syndrome · Haydarpasa Numune Training and Research Hospital
- Sep 2027Strain-Counterstrain Treatment of Piriformis Pain · Loma Linda University
Who these studies take
Of the 13 Piriformis Muscle Syndrome studies recruiting now, 0 (0%) set no upper age limit and 11 (85%) stop at 75 or younger. 0 (0%) take children under 18. 4 (31%) are for women only and 0 (0%) for men only; 3 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 4 (31%) | 4 (31%) |
| 30 | 13 (100%) | 9 (69%) |
| 40 | 12 (92%) | 8 (62%) |
| 50 | 9 (69%) | 6 (46%) |
| 65 | 5 (38%) | 4 (31%) |
| 75 | 2 (15%) | 2 (15%) |
| 85 | 1 (8%) | 1 (8%) |
Across all 58 studies, recruiting or not: 86% stop at 75 or younger and 72% at 65; 0% take children; 14% are for women only and 0% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Piriformis Muscle Syndrome studies take
Of 39 interventional studies with no phase under Piriformis Muscle Syndrome, half reached primary completion within 6 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 6 mo4–12 · 39 studies | — | 6 mo4–12 · 39 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Newly registered1
- Comparing Strain Counterstrain and Active Release for Piriformis SyndromeNov 9, 2026NCT07925320
Studies
Recruiting first, then most recently updated. Showing 50 of 58. Browse all 58 → or search them.
- Efficacy of Botulinum Toxin Versus Placebo on Pain and Health Related Quality of Life of Patients With Piriformis Muscle SyndromeNot yet recruitingNCT07624045Phase 21 country
- Interfascial Hydrodissection Added to Ultrasound-Guided Piriformis Injection for Piriformis SyndromeRecruitingNCT07813455Not applicable1 country
- Comparative Effects of Post-Isometric Relaxation and Reciprocal Inhibition Techniques inPiriformis SyndromeRecruitingNCT07646314Not applicable1 country
- Comparative Effects of Stecco-fascial Manipulation and Rolfing Structural Integration in Patients With Piriformis SyndromeEnrolling by invitationNCT07322185Not applicable1 country
- Comparing Two Soft Tissues Technique on Piriformis Syndrome PatientsNot yet recruitingNCT07661485Not applicable1 country
- Comparative Effects Of Post Isometric Relaxation Versus Active Isolated Stretch In Patients With Piriformis SyndromeRecruitingNCT07526012Not applicable1 country
- Strain-Counterstrain Treatment of Piriformis PainRecruitingNCT05023005Not applicable1 country
- Telerehabilitation vs. Home Exercise in Piriformis Syndrome: A Comparative StudyEnrolling by invitationNCT07502573Not applicable1 country
- Diagnostic Accuracy of Clinical Tests and Diagnostic Criteria for Piriformis SyndromeNot yet recruitingNCT07473349Not applicable1 country
- Ultrasound-Guided Interfascial Hydrodissection for Gluteal Myofascial Pain in Piriformis Syndrome: A Prospective StudyNot yet recruitingNCT07326982Not applicable1 country
- Instrument-Assisted Soft Tissue Mobilization Versus PNF Stretching in Athletes With Piriformis SyndromeRecruitingNCT07090356Not applicable1 country
- Effects of Facilitated Positional Release Technique ( FPRT) Vs Manual Myofascial Release Technique in Female Patients With Piriformis Syndrome.RecruitingNCT07044869Not applicable1 country
- Chronic Pelvic Pain in Females and MalesRecruitingNCT061027331 country
- Radial Shockwave Versus Low Level Laser Therapy in Patients With Chronic Piriformis Muscle SyndromeNot yet recruitingNCT06762197Not applicable1 country
- "Effects of Facilitated Positional Release Technique( FPRT) Vs. Manual Myofascial Release Technique in Female Patients With Piriformis SyndromeRecruitingNCT06753487Not applicable1 country
- Comparasion of Autogenic Inhibition and Reciprocal Inhibition Muscle Energy Techniques (METS) in Piriformis SyndromeRecruitingNCT06460675Not applicable1 country
- Comparison of Effectiveness Between Active Release Technique and Hold Relax Technique in Patients With Piriformis SyndromeRecruitingNCT06437327Not applicable1 country
- Effectiveness of Instrument Assisted Soft Tissue Mobilization in Management of Piriformis SyndromeRecruitingNCT06406023Not applicable1 country
- The Effects of Ultrasound Guided Ozone and Lidocaine Injections in Piriformis SyndromeRecruitingNCT06130618Not applicable1 country
- Comparison of Ultrasound-guided Steroid Injection and Dry Needling in Piriformis Muscle SyndromeNot yet recruitingNCT06095180Not applicable
- Muscle Energy Technique and Stretching Exercise in Working Pregnant Women With Piriformis SyndromeRecruitingNCT05915858Not applicable1 country
- Ultrasound-guided vs. Blinded Dry Needling for Piriformis SyndromeNot yet recruitingNCT05882799Not applicable
- Effects of MET and MFR on Piriformis SyndromeActive, not recruitingNCT07769203Not applicable1 country
- Ultrasonographic Evaluation of the Sciatic Nerve in Patients With Piriformis SyndromeCompletedNCT067834391 country
- Comparing Strain Counterstrain and Active Release for Piriformis SyndromeActive, not recruitingNCT07925320Not applicable1 country
- Investigation of the Relationship Between Pes Planus and Piriformis Syndrome: A Case-Control StudyCompletedNCT076744331 country
- Comparison of Laser and Shockwave Therapy for Piriformis Syndrome With Adjunctive ExerciseCompletedNCT07567703Not applicable1 country
- Comparative Effects of Post Facilitation Stretch and Active Release Technique in Female Patients With Piriformis Syndrome.CompletedNCT07547059Not applicable1 country
- f-ESWT vs Steroid Injection for Piriformis SyndromeCompletedNCT07145554Not applicable1 country
- Effects of Hip Abductor Strengthening Exercises in Patients With Piriformis SyndromeCompletedNCT07484373Not applicable1 country
- McGill Strengthening With and Without Integrated Neuromuscular Inhibition Technique in Piriformis SyndromeCompletedNCT07403045Not applicable1 country
- Foam Rolling and Dynamic Stretching in Piriformis SyndromeActive, not recruitingNCT07278193Not applicable1 country
- Comparative Effects of PIR and PFS on Pain, Hip ROM, and Disability in Piriformis SyndromeCompletedNCT07255053Not applicable1 country
- Effects of KinesioTaping Versus Dry Needling in the Treatment of Sacroiliac Joint Pain Among Females.CompletedNCT06755125Not applicable1 country
- Effects of Neural Mobilization and Stretching in Piriformis SyndromeCompletedNCT06808659Not applicable1 country
- Piriformis Syndrome; Extracorporeal Shock Wave Therapy and Dry NeedlingCompletedNCT06530862Not applicable1 country
- Trochanteric Bursal Repair After a Total Hip Replacement - Are There Benefits During the First 90 DaysCompletedNCT06553508Not applicable1 country
- Effects of Reciprocal Inhibition Versus Post Facilitation Muscle Energy Technique Along With Conventional Physical Therapy in Patients With Piriformis Syndrome: a Randomized Controlled TrialStatus unknownNCT06534788Not applicable1 country
- Investigation of the Presence of Piriformis Syndrome Accompanying Lumbar RadiculopathyCompletedNCT05392933Not applicable1 country
- Effectiveness of Dry Needling Versus Cupping Therapy for Pain in Piriformis SyndromeActive, not recruitingNCT06437795Not applicable1 country
- Comparative Presence of Piriformis Syndrome in Patients With Lumbar Disc Bulging and ProtrusionCompletedNCT064351691 country
- Effects of Global Hip Versus Isolated Abductors Strengthening Exercises in Patients Withsecondary Piriformis SyndromeCompletedNCT05848063Not applicable1 country
- Comparative Effect of Active Release Technique Versus Self-myofascial Release in Improving Piriformis SyndromeCompletedNCT05742633Not applicable1 country
- Efficacy of Ultrasound-Guided Dry Needling Therapy and Exercise in Piriformis Muscle SyndromeCompletedNCT059625151 country
- Effect of Ultrasound-guided Piriformis Muscle Corticosteroid Injection Versus Extracorporeal Shock Wave Therapy for Piriformis Syndrome: a Randomized Control TrialCompletedNCT04684537Not applicable1 country
- Effects of Hold Relax With Agonist Contraction and Active Release Therapy on Clinical Outcomes in Piriformis SyndromeCompletedNCT05370378Not applicable1 country
- Effects of Soft Tissue Mobilization Technique and Piriformis Muscle Stretching Among Patients Having Piriformis SyndromeCompletedNCT05680402Not applicable1 country
- Self Myofascial Release in Individuals With Piriformis SyndromeCompletedNCT05660005Not applicable1 country
- Frequency of Piriformis Syndrome:Does the Presence of One Pathology Rule Out the Other?Status unknownNCT05450913Not applicable
- Graston Technique in Deep Gluteal SyndromeCompletedNCT04387877Not applicable1 country