An interventional study of Micellar Water Application (No Rinse) and Micellar Water Application (With Rinse) in Effects of Micellar Water Application on Skin Barrier Integrity, Hydration, and Erythema in Healthy Skin, sponsored by University of Split, School of Medicine. Active, not recruiting at 1 site in Croatia. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-07-23.
Sponsored by University of Split, School of Medicine · Not applicable, Interventional, and Basic science
The goal of this clinical trial is to assess how micellar water affects the skin barrier in healthy adult volunteers. The main questions it aims to answer are:
Researchers will compare the effects of micellar water left on the skin versus rinsed off after application.
Participants will:
University of Split, School of Medicine is the lead sponsor of 49 studies on the registry; 16 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants apply micellar water to the forehead once daily and leave it on the skin without rinsing. Skin barrier function is assessed before and after 21 days of application.
Procedure: Micellar Water Application (No Rinse)
Participants apply micellar water to the forehead once daily and rinse it off after application. Skin barrier function is assessed before and after 21 days of application.
Procedure: Micellar Water Application (With Rinse)
Participants apply micellar water to the forehead once daily and leave it on the skin without rinsing for 21 days.
Participants apply micellar water to the forehead once daily and rinse it off after application for 21 days.
Change in TransEpidermal Water Loss (TEWL)
Measurement of transepidermal water loss on the forehead to assess skin barrier function.
Time frame: Four measurements total: one at baseline (before application), and one at the start of each week during the 3-week intervention (Days 0, 7, 14, and 21).
Change in Skin Hydration
Measurement of skin hydration levels on the forehead before and after micellar water application.
Time frame: Four measurements total: one at baseline (before application), and one at the start of each week during the 3-week intervention (Days 0, 7, 14, and 21).
Change in Erythema
Assessment of skin redness (erythema) on the forehead before and after of micellar water application.
Time frame: Four measurements total: one at baseline (before application), and one at the start of each week during the 3-week intervention (Days 0, 7, 14, and 21).
This study is active, not recruiting, as verified in Jun 2025. You cannot join it, but the record below documents what was studied.
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University of Split, School of Medicine