An observational study in Small Cell Lung Cancer ( SCLC ) and Lambert Eaton Myasthenic Syndrome (LEMS), sponsored by Addario Lung Cancer Medical Institute. Withdrawn at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-04.
Sponsored by Addario Lung Cancer Medical Institute · Observational
This is a multi-center observational study in subjects with a diagnosis of small cell lung cancer. Screening and/or medical record review for symptoms associated with Lambert Eaton Myasthenic Syndrome (LEMS) will be conducted.
This is a multi-center observational study in subjects with a diagnosis of small cell lung cancer. All eligible subjects enrolled will undergo a brief, symptom directed neurological evaluation and VGCC antibody testing (to be performed at a participating Quest laboratory). The results (positive/negative) of VGCC antibody testing will be documented as well as the receptor type P, Q or N.
These tests will be repeated quarterly (Q3 months) for the duration of the study.
If at any visit the subject is found to be BOTH neurologically suggestive of having LEMS and the VGCC Ab test is positive, then the subject is considered to be Clinically Suspicious of having LEMS. At any visit if a subject meets the criteria of Clinically Suspicious of LEMS. the end of study visit will be completed. Once the End of study visit is completed no further treatment information will be collected.
1,203 studies on the registry are indexed under Small Cell Lung Carcinoma; 342 are open to participants now.
Browse Small Cell Lung Carcinoma studies →Addario Lung Cancer Medical Institute is the lead sponsor of 10 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
United States
Exclusion Criteria:
Diagnosis of SCLC within 1 year of enrollment
Suspicious LEMS
Incidence of clinically suspicious LEMS diagnosis
Time frame: 1 year
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This study is withdrawn, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Addario Lung Cancer Medical Institute