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Active, not recruitingNCT07072416Updated Jul 22, 2025

Aquatic Based Exercises Versus Mirror Therapy on Hand Dexterity and Strength in Hemiplegic Child

An interventional study of Aquatic Exercise and Mirror Therapy in Cerebral Palsy (CP) and Hemiplegia and Hemiparesis, sponsored by Alaa Noureldeen Kora. Active, not recruiting at 1 site in Egypt. Open to participants aged 6 Years to 12 Years. Per ClinicalTrials.gov, last updated 2025-07-22.

Sponsored by Alaa Noureldeen Kora · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Aug 2025, 1 year 1 month ago, but the record still lists the study as active, not recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
45
Allocation
Randomized
Ages
6 Years to 12 Years
Sex
All
01

Study summary

Cerebral palsy (CP) is a neurologic disorder that affects motor function, balance, and posture, and spastic hemiplegia is found in about one-third of persons with CP and often leads to devastating upper limb disability. Rehabilitation interventions such as aquatic therapy and mirror therapy are commonly utilized to improve motor function and functional independence. Water therapy takes advantage of water resistance and buoyancy to relax tightened muscles, promote gross motor function, and increase muscle endurance and strength with studies showing significant improvements in motor skills as well as a reduction in spasticity in CP children, especially hemiplegic children. Water therapy can also be more enjoyable and convenient for kids, but safety has to be considered. Mirror therapy does utilize visual feedback, but to cause the movement in the paralyzed limb, and can increase hand dexterity and grip strength by stimulating the neural pathways through the illusion of movement. Although aquatic therapy has shown well-defined advantages in motor functioning and muscle tone, comparison of the efficacy of aquatic exercises and mirror therapy for hand dexterity and grip strength in hemiplegic CP has been limited, and further studies are indicated to establish their relative merits and potential complementary uses.

Read the detailed description

Cerebral palsy (CP) is a neurological impairment of motor disorder, balance, movement disorder, and postural deformities that appear during infancy and early childhood, although muscle tone and posture related abnormalities becomes more prominent in later years . Globally CP occurs 1.5 to more than 4 per 1000 live births.

One of the types of CP is spastic hemiplegia, known as half-body paralysis and the prevalence is about 35.1% of all children with CP . Upper limb function impairment is a common and disability consequence of problems in reaching, pointing, and taking, releasing and manipulating objects . The ability to reach and grasp things is one of the basic tasks in activities of daily living.

Multiple approaches in the physical therapy are being used in the rehabilitation of CP such as stretching, strengthening, Neuro-developmental technique (NDT), motor relearning programs in reducing the spasticity and improving functional level in CP (Dimitrijević et al., 2012). During current practices, primary focus on improving the functional independency and motor skills, thus aquatic therapy is good approach in this regard (Declerck et al., 2013).

Furthermore, hydrotherapy is effective treatment mode due to buoyancy and hydrostatic properties of water. Buoyancy force is equal to the weight of the fluid displaced by the object. According the hydrotherapy is an effective treatment option in CP due to its thermal and mechanical effects.

Thermal effects relax the muscle and facilitates in reducing the spasticity while mechanical effects of water are sufficient in reducing the effect of gravity and minimizing the joint loading, furthermore, water provides enjoyable environment to perform multiple functional activities for cerebral palsy (Getz et al., 2012). Exercises in the pool are always performed at the temperature of 33°- 35oC that is essential in reducing the spasticity by relaxing the muscles (Adar et al., 2017). Besides these effects hydrotherapy has effects on strengthening the muscles and endurance since water creates resistance during walking that strengthens the muscles (Khalaji et al., 2017). Activities performed in water are easier and effective as compared to the land but it has a major safety issue that should be identified before the start of exercises for the better results (Adar et al., 2017). Hydrotherapy has several positive effects in the management of spasticity, joint range of motion and improving balance in CP. Since the aquatic exercise reduces spasticity thus has potential effects in improving the gross motor functions among CP.

Among non-invasive approaches, mirror therapy is a relatively new approach that focuses on visual stimulation and the movements of limbs without damage. The reflection of the healthy limb movement in the mirror is thought the affected limb is moving naturally (Fukumura et al., 2007). In this method, the patient places his hands on the two sides of the mirror. Thus, the patient understands the reflection of his healthy hand in the mirror as his affected hand (Mc Cabe et al., 2008).

Statement of problem:

Is there difference between effects of aquatic based exercises and mirror therapy on hand dexterity and hand grip strength in children with hemiplegic cerebral palsy?

Purpose of study:

The purpose of this study is:

  • To investigate the effect of aquatic based exercises and mirror therapy on hand dexterity and hand grip strength in children with hemiplegic cerebral palsy
  • To investigate the correlations between the effects of aquatic based exercises, mirror therapy and control group on hand dexterity and hand grip strength in children with hemiplegic cerebral palsy.
02

Conditions studied

  • Cerebral Palsy (CP)
  • Hemiplegia and Hemiparesis

Keywords

  • Aquatic Based Exercises
  • Hemiplegic Child
  • Hand Dexterity
  • Mirror Therapy
  • Hand Strenght
  • Cerebral Palsy
03

In context

Cerebral Palsy

1,853 studies on the registry are indexed under Cerebral Palsy; 435 are open to participants now.

This study's enrollment of 45 is above the median of 33 across 1,368 interventional studies indexed under Cerebral Palsy.

Browse Cerebral Palsy studies →

Lead sponsor

Alaa Noureldeen Kora is the lead sponsor of 2 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
6 Years to 12 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Children with Hemiplegic cerebral palsy
  • Children with mild to moderate spasticity of wrist muscles spasticity will range between (0-4) score according to Modified Ashworth Scale.
  • Children will be able to follow the instructions.
  • Children without any genetic disorders.

Exclusion criteria

Exclusion Criteria:

  • Cognitive impairment.
  • Unilateral neglect disorders.
  • Orthopedic dysfunction.
  • Visual impairment.
  • Verbal impairment.
  • Open wound or infection
  • Fixed contractures.
  • Previous limb surgeries within 6 months.
  • Resting angina.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
45 participants (actual)

Study arms

  • Experimental
    Group 1: Aquatic Therapy

    Children in Group A will receive aquatic based exercises and a designed physical therapy program

    Other: Aquatic Exercise · Other: Designed physical therapy program.

  • Experimental
    Group 2: Mirror Therapy

    Group B will receive mirror therapy and a designed physical therapy program

    Other: Mirror Therapy · Other: Designed physical therapy program.

  • Other
    Group 3: Control Group

    Control Group (C) will receive a designed physical therapy program.

    Other: Designed physical therapy program.

Interventions

  • OtherAquatic Exercise

    Aquatic exercise or hydrotherapy, involving the performance of physical exercise in water, has been determined to have an assortment of beneficial health impacts on healthy individuals and those with chronic diseases. Aquatic exercise has been determined to enhance strength, balance, flexibility, and the quality of life, particularly among groups like postmenopausal women, patients with osteoarthritis, Parkinson's disease, and type 2 diabetes

  • OtherMirror Therapy

    Mirror therapy is a type of rehabilitation where visual feedback is employed to induce movement and recovery in an affected limb by asking the patients to observe the reflection of their healthy limb in a mirror, giving the illusion that both limbs are moving normally.

  • OtherDesigned physical therapy program.

    The program will start with 10 minutes of poolside exercises including warming up, active range of motion and stretching followed by 20 minutes of aquatic exercise in the pool. The pool session consists of 20 minutes of active range of motion, stretching and strengthening exercises

06

What researchers measure

Primary outcomes

  1. Box and Block Test: It was used to assess gross manual dexterity

    The Box and Block Test (BBT) is a widely used test to evaluate gross manual dexterity by rehabilitation centers and occupational therapy clinics. The individual has to move as many blocks as possible from one of the compartments of a box to the other in a given time period, usually one minute, using one hand at a time. The BBT is valued for simplicity, ease of use, and strong reliability and validity across the lifespan, and in clinical populations like children, adults, and those with neurological or musculoskeletal disorder

    Time frame: 3 Months

  2. Hand held dynamometer to assess hand grip strength.

    A popular, trustworthy, and legitimate tool for evaluating hand grip strength-a crucial sign of general muscle function and health-is a hand-held dynamometer.

    Time frame: 3 Months

07

Study locations

1 site
  • Damanhur Medical National Institute Hospital
    Damanhur, Beheira 5844152, Egypt
08

References and documents

Publications

  • Adar S, Dundar U, Demirdal US, Ulasli AM, Toktas H, Solak O. The effect of aquatic exercise on spasticity, quality of life, and motor function in cerebral palsy. Turk J Phys Med Rehabil. 2017 Aug 14;63(3):239-248. doi: 10.5606/tftrd.2017.280. eCollection 2017 Jun. PubMed 31453460 ↗
  • Roostaei M, Baharlouei H, Azadi H, Fragala-Pinkham MA. Effects of Aquatic Intervention on Gross Motor Skills in Children with Cerebral Palsy: A Systematic Review. Phys Occup Ther Pediatr. 2017 Oct 20;37(5):496-515. doi: 10.1080/01942638.2016.1247938. Epub 2016 Dec 14. PubMed 27967298 ↗
  • El-Shamy SM. Effects of Antigravity Treadmill Training on Gait, Balance, and Fall Risk in Children With Diplegic Cerebral Palsy. Am J Phys Med Rehabil. 2017 Nov;96(11):809-815. doi: 10.1097/PHM.0000000000000752. PubMed 28410250 ↗
  • Lai CJ, Liu WY, Yang TF, Chen CL, Wu CY, Chan RC. Pediatric aquatic therapy on motor function and enjoyment in children diagnosed with cerebral palsy of various motor severities. J Child Neurol. 2015 Feb;30(2):200-8. doi: 10.1177/0883073814535491. Epub 2014 Jun 5. PubMed 24907137 ↗
  • Ryu K, Ali A, Kwon M, Lee C, Kim Y, Lee G, Kim J. Effects of assisted aquatic movement and horseback riding therapies on emotion and brain activation in patients with cerebral palsy. J Phys Ther Sci. 2016 Dec;28(12):3283-3287. doi: 10.1589/jpts.28.3283. Epub 2016 Dec 27. PubMed 28174435 ↗
  • Stavsky M, Mor O, Mastrolia SA, Greenbaum S, Than NG, Erez O. Cerebral Palsy-Trends in Epidemiology and Recent Development in Prenatal Mechanisms of Disease, Treatment, and Prevention. Front Pediatr. 2017 Feb 13;5:21. doi: 10.3389/fped.2017.00021. eCollection 2017. PubMed 28243583 ↗

Individual participant data

Plan to share: No — It will provided only upon reasonable request

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 22, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07072416
Lead sponsor
Alaa Noureldeen Kora
Responsible party
Alaa Noureldeen Kora (Assistant Professor, Cairo University) — Sponsor-investigator
First posted
Jul 18, 2025
Start date
May 1, 2025
Primary completion
Aug 30, 2025 (estimated)
Completion
Sep 30, 2025 (estimated)
Last update
Jul 22, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.

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