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RecruitingNCT07069452Updated Jul 16, 2025

Prognostic Value of Isolated and Combined Score Aspects in Acute Ischemic Stroke

An observational study in Stroke, Ischemic, Thrombectomy and Thrombolytic Therapy, sponsored by Centre Hospitalier de Gonesse. Recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-07-16.

Sponsored by Centre Hospitalier de Gonesse · Observational

From the registry’s dates

  • Primary completion was expected by Jan 2026, 9 months ago, but the record still lists the study as recruiting.
  • Started Apr 2025; still recruiting 1 year 6 months later.
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
152
Ages
18 Years and older
Sex
All
01

Study summary

This study, called TARGET-ASPECT, looks at patients who had a type of stroke called acute ischemic stroke and were treated with clot-busting medicine and a procedure to remove the clot. Even with these treatments, about half of patients don't fully recover. The study aims to see if certain brain imaging scores, especially when combined, can better predict how well patients will recover 90 days after their stroke and if their blood vessels reopen successfully. The study will include 152 patients and last about 9 months. The goal is to find easy and reliable tools that doctors can use to make better treatment decisions.

02

Conditions studied

  • Stroke, Ischemic
  • Thrombectomy
  • Thrombolytic Therapy
  • Brain Ischemia
  • Prognosis
  • Magnetic Resonance Imaging
  • Outcome Assessment (Health Care)
03

In context

Ischemic Stroke

2,612 studies on the registry are indexed under Ischemic Stroke; 971 are open to participants now.

This study's planned enrollment of 152 is below the median of 300 across 771 observational studies indexed under Ischemic Stroke.

Browse Ischemic Stroke studies →

Lead sponsor

Centre Hospitalier de Gonesse is the lead sponsor of 15 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

The study population consists of adult patients (aged 18 and over) who have experienced an acute ischemic stroke confirmed by imaging. These patients have undergone combined treatment with thrombolysis (clot-busting medication) and thrombectomy (mechanical clot removal). They are selected from a single medical center where detailed clinical and imaging follow-up data, including functional outcomes at 90 days, are available. Participants must have adequate-quality imaging and not have experienced early death or loss to follow-up before evaluation.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients aged 18 years or older
  • Confirmed acute ischemic stroke on imaging
  • Treated with both thrombolysis and thrombectomy
  • Clinical follow-up data available at 90 days (mRS score)

Exclusion criteria

Exclusion Criteria :

  • Primary hemorrhagic stroke
  • Early death or loss to follow-up without evaluation
  • Poor-quality imaging that cannot be analyzed
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
152 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Favorable functional outcome defined as a mRS score of 0 to 2 at 90 days

    Time frame: 90 days

07

Study locations

1 of 1 sites recruiting
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 16, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07069452
Lead sponsor
Centre Hospitalier de Gonesse
Responsible party
Sponsor
First posted
Jul 16, 2025
Start date
Apr 15, 2025
Primary completion
Jan 15, 2026 (estimated)
Completion
Jan 15, 2026 (estimated)
Last update
Jul 16, 2025

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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