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Not yet recruitingNCT07062718Updated Jul 14, 2025

Median Nerve Flossing Technique in Patients With Cervical Radiculopathy

An interventional study of Median nerve flossing technique and conventional physical therapy and Conventional physical therapy in Cervical Radiculopathy, sponsored by Riphah International University. Not yet recruiting at 1 site in Pakistan. Open to participants aged 30 Years to 50 Years. Per ClinicalTrials.gov, last updated 2025-07-14.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Sep 2025, 1 year ago, but the record still lists the study as not yet recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
38
Allocation
Randomized
Ages
30 Years to 50 Years
Sex
All
01

Study summary

Cervical radiculopathy is a condition of cervical spinal nerve roots which occurs as a result of compression and inflammatory pathology from a space occupying lesion. Nerve flossing technique is a quick mobilization of the strained nerves which will reduce pain .This study aim to determine the effects of nerve flossing technique on pain, range of motion and disability in patients with cervical radiculopathy.

Read the detailed description

This study will be a randomized controlled trial and will be conducted in Riphah Rehabilitation Clinic Lahore and Shalamar Hospital(physiotherapy department) Lahore. Non-probability convenient sampling will be used to collect the data. Sample size of 38 subjects with age group between 30 to 50 years will be taken. Data will be collected from the patients having unilateral median nerve symptoms of cervical radiculopathy. Outcome measures will be taken using Numeric pain rating scale(NPRS) for pain, Neck disability index (NDI) and Universal Goniometer (GU) for Range of motion. An informed consent will be taken. Subjects will be selected on the basis of inclusion and exclusion criteria and will be equally divided into two group by convenience sampling. Both the Groups will receive Transcutaneous electrical nerve stimulation (TENS), Hot Pack, cervical isometric and cervical stretching , while Group A will receive conventional treatment and Group B will receive an additional nerve flossing technique. Outcome measures, Numeric Pain Rating scale (NPRS) for pain ,Neck Disability Index (NDI) for disability and Universal Goniometer for range of motion will be measured at baseline and after 3 weeks of treatment total 12 sessions(4 sessions per week ).Data analysis will be done by SPSS version 21.0.

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Conditions studied

  • Cervical Radiculopathy

Keywords

  • pain
  • range of motion
  • disability
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In context

Radiculopathy

488 studies on the registry are indexed under Radiculopathy; 141 are open to participants now.

This study's planned enrollment of 38 is below the median of 60 across 376 interventional studies indexed under Radiculopathy.

Browse Radiculopathy studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,133 studies on the registry; 633 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
30 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
No

Eligibility criteria

Inclusion Criteria:• Both male and female gender were included

  • Participants with 30 to 50 years of age group were taken in this study (Gore et al., 2020)
  • Patients with positive Spurling test ,cervical distraction ,cervical rotation test were included
  • Participants with positive Upper limb neural tension test for median nerve were taken into consideration
  • Patients who are having radicular symptoms and pain for more than 3 months were included

Exclusion Criteria:

  • Systematic disorders affecting musculoskeletal disorders e.g. Ankylosing spondylitis,rheumatic arthritis etc.
  • Patient with primary shoulder or upper limb pain origin
  • Patients with severe malignancy,COPD ,isch
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
38 participants (estimated)

Study arms

  • Active comparator
    Median nerve flossing technique and conventional physical therapy

    Nerve flossing will be started from root along brachial plexus,median nerve root. Before starting the procedure ,subjects will be shown the flossing technique as it will be performed actively by the subjects. Each flossing will be performed with 10 repetitions starting from neck,arm,elbow,wrist and whole nerve flossing (12). It will be a 3 week treatment with 4 session per week (12 sessions) (12).

    Other: Median nerve flossing technique and conventional physical therapy

  • Active comparator
    Conventional physical therapy

    The subjects in this group will be treated with TENS and hot pack. All the subjects will be screened according to the inclusion and exclusion criteria .Written informed consent will be taken from all the subjects before the treatment. The subjects will be allowed to withdraw the treatment any time.The subjects will be divided into 2 groups through convenience sampling.All the subjects from both group will be given trancutaneous electric nerve stimulation TENS ,hot pack, isometrics and stretching as a conventional physical therapy followed by respective group techniques The session will last for 20 -25 minutes , TENS pad will be placed in the suboccipital region and the trapezius unilaterally with hot pack simultaneously for 10 minutes

    Other: Conventional physical therapy

Interventions

  • OtherMedian nerve flossing technique and conventional physical therapy

    Median nerve flossing technique and conventional physical therapy Nerve flossing will be started from root along brachial plexus,median nerve root. Before starting the procedure ,subjects will be shown the flossing technique as it will be performed actively by the subjects. Each flossing will be performed with 10 repetitions starting from neck,arm,elbow,wrist and whole nerve flossing (12). It will be a 3 week treatment with 4 session per week (12 sessions)

    Also known as: conventional physical therapy

  • OtherConventional physical therapy

    The subjects in this group will be treated with TENS and hot pack. All the subjects will be screened according to the inclusion and exclusion criteria .Written informed consent will be taken from all the subjects before the treatment. The subjects will be allowed to withdraw the treatment any time.The subjects will be divided into 2 groups through convenience sampling.All the subjects from both group will be given trancutaneous electric nerve stimulation TENS ,hot pack, isometrics and stretching as a conventional physical therapy followed by respective group techniques The session will last for 20 -25 minutes , TENS pad will be placed in the suboccipital region and the trapezius unilaterally with hot pack simultaneously for 10 minutes

06

What researchers measure

Primary outcomes

  1. numeric pain rating scale

    The intensity of pain was assessed with the help of NPRS. The scale have readings that numerate from 0 to 10,beginning with least reading 0 that indicates no pain ,5 indicates moderate level of pain and 10 indicates extreme level of pain.Test-retest reliability of NPRS was high

    Time frame: 4 weeks

Secondary outcomes

  1. goniometer

    Universal goniometer was used to measure range of motion of cervical region that has an inter-rater reliability

    Time frame: 4 weeks

Other outcomes

  1. universal goniometer

    Disability level of neck was demonstrated by using Neck Disability Index (NDI) questionnaire .It consist of total 10 sections, each with 0-5 rating scale in which 0 indicates "

    Time frame: 4 weeks

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Study locations

1 site
  • Dr Asif Clinic
    Lahore, Punjab Province 54920, Pakistan
08

References and documents

Publications

  • Anandkumar S. The effect of sustained natural apophyseal glide (SNAG) combined with neurodynamics in the management of a patient with cervical radiculopathy: a case report. Physiother Theory Pract. 2015 Feb;31(2):140-5. doi: 10.3109/09593985.2014.971922. Epub 2014 Oct 20. PubMed 25329587 ↗
  • Childs JD, Piva SR, Fritz JM. Responsiveness of the numeric pain rating scale in patients with low back pain. Spine (Phila Pa 1976). 2005 Jun 1;30(11):1331-4. doi: 10.1097/01.brs.0000164099.92112.29. PubMed 15928561 ↗
  • Cleland JA, Childs JD, McRae M, Palmer JA, Stowell T. Immediate effects of thoracic manipulation in patients with neck pain: a randomized clinical trial. Man Ther. 2005 May;10(2):127-35. doi: 10.1016/j.math.2004.08.005. PubMed 15922233 ↗
  • Dimitrov, T., Hussain, N., & Abd-Elsayed, A. (2022). Median Nerve. Peripheral Nerve Stimulation-E-Book: A Comprehensive Guide, 82.
  • Farooq MN, Mohseni Bandpei MA, Ali M, Khan GA. Reliability of the universal goniometer for assessing active cervical range of motion in asymptomatic healthy persons. Pak J Med Sci. 2016 Mar-Apr;32(2):457-61. doi: 10.12669/pjms.322.8747. PubMed 27182261 ↗
  • Gore, V., Patil, H., & Chogule, A. (2020). Effect of Cervical Manual Traction, TENS and Neural Tissue Mobilization on Pain and Functional Disability in Unilateral Cervical Radiculopathy. Website: Www. Ijrrjournal. Com Original Research Article International Journal of Research and Review (Ijrrjournal. Com), 7(10), 198-200.
  • omparison of Treatment Outcome of the Effectiveness of Isometric Exercises as Hayat, M., Siddique, R., Basharat, A., Waheed, I., Rubab, S. U., Naqvi, H., . . . Haq, F. (2023). Compared to General Exercises with Cervical Spine Mobilization in The Management of Chronic Non Specific Neck Pain. British Journal of Multidisciplinary and Advanced Studies, 4(6), 63-72.
  • Kage, V., & Gurav, G. (2017). Effect of neural flossing technique on pain, cervical range of motion and functional ability in subjects with acute, sub-acute trapezitis: An experimental study. Int. J. Appl. Res, 3, 818-822.
  • Karkousha, R. N., Selem, A. I., Aly, S. A., & Zahran, M. R. (2023). Mulligan mobilization technique versus neural mobilization on nerve root function in patients with cervical radiculopathy: Randomized controlled trial. Revista iberoamericana de psicología del ejercicio y el deporte, 18(6), 670-675.

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 14, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07062718
Lead sponsor
Riphah International University
Responsible party
Sponsor
First posted
Jul 14, 2025
Start date
Jul 25, 2025 (estimated)
Primary completion
Sep 20, 2025 (estimated)
Completion
Oct 20, 2025 (estimated)
Last update
Jul 14, 2025

Study contacts

Iqra Shahbaz, MS student
Contact
iqrashahbaz1286@gmail.com
03059374260
Muzna Munir, PHD scholar
Contact
muznafmh@gmail.com
03344265125
Asif Sheikh, MBBS FCPS
study chair · Pediatric clinic

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is not yet recruiting, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.

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