An interventional study of lipid profile in Acne Vulgaris, sponsored by Sohag University. Not yet recruiting at 1 site in Egypt. Open to participants aged 12 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-07-14.
Sponsored by Sohag University · Not applicable, Interventional, and Screening
Acne vulgaris is the most common skin condition affecting late adolescents worldwide.1 The prevalence of acne is said to be 85% in adults aged 12 to 25 years.2 Almost all teenagers between 15 and 17 years report having some degree of acne.3 Estimates of the lifetime occurrence of acne in the literature range from 0.1%4 to as high as 85.1%5 in the general population, depending on the age range, region, and method of sampling. Overall, acne is more common in women,8,9 but in some literature the prevalence is approximately equal in men and women.10,11
Acne vulgaris is a multifactorial disorder of the pilosebaceous unit, resulting from sebum overproduction, follicular hyperkeratinization, inflammation, and bacterial colonization of hair follicles by Propionibacterium acnes. The sebaceous gland is controlled primarily by hormonal stimulation. In this way, the hormonal effect on sebum secretion is a key to the pathogenesis of acne.12-16 During puberty, alteration of the sebum component, called dysseborrhea, stress, irritation, cosmetics, and potential dietary factors lead to the formation of acne lesions.16 Changes in sebum secretion are considered to be an important factor of acne. In this way, increased sebum secretion can induce acne occurrence.17 Increasing evidence, in essence, indicates that changes in lipid profile are strongly related to acne occurrence. Accordingly, further information and awareness campaigns are needed to emphasize the role of balanced lipid metabolism to control acne. Although a correlation between the incidence of acne and lipid profile levels has been observed before, it must be documented in each population with etiological characteristics. Minimal reports are available on the relationship between plasma lipids and acne in our country. Hence, we aim to establish this study to estimate the presence of lipid alteration in acne patients.
730 studies on the registry are indexed under Acne Vulgaris; 86 are open to participants now.
This study's planned enrollment of 100 is above the median of 69 across 628 interventional studies indexed under Acne Vulgaris.
Browse Acne Vulgaris studies →Sohag University is the lead sponsor of 1,183 studies on the registry; 612 are open to participants now.
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Exclusion Criteria:
: reluctance to take part in the study, pregnancy or lactation
The blood samples were taken to measure lipid profile levels as triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL), and high-density lipoprotein cholesterol (HDL) and VLDL values.
lipid profile (TG)
The blood samples were taken to measure lipid profile levels as triglycerides (TG)
Time frame: 6 months
lipid profile (HDL)
The blood samples were taken to measure lipid profile levels as HDL
Time frame: 6 months
lipid profile (VLDL)
The blood samples were taken to measure lipid profile levels as VLDL
Time frame: 6 months
Plan to share: Undecided
This study is not yet recruiting, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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Sohag University