An interventional study of Moderately intense exercise and MetFORMIN 500 Mg Oral Tablet in Pre Diabetic and Pre Diabetes, sponsored by Asad Ullah Jan. Completed at 1 site in Pakistan. Open to participants aged 18 Years to 59 Years. Per ClinicalTrials.gov, last updated 2026-05-07.
Sponsored by Asad Ullah Jan · Not applicable, Interventional, and Treatment
This study is being done to compare the effect of regular exercise and metformin in people who have prediabetes. It is a community-based, open-label, randomized trial in which eligible participants will be divided into two groups. One group will do moderate physical exercise, and the other group will take metformin for 12 weeks. We will check their fasting blood sugar and HbA1c before and after the treatment to see which method works better for controlling sugar levels. The study is being done in a low-resource community setup to see which option is more practical and effective in real-life Pakistani settings.
778 studies on the registry are indexed under Glucose Intolerance; 129 are open to participants now.
This study's enrollment of 226 is above the median of 60 across 645 interventional studies indexed under Glucose Intolerance.
Browse Glucose Intolerance studies →Asad Ullah Jan is the lead sponsor of 4 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Moderate aerobic activity (e.g., brisk walking) for 30-45 minutes/day, 5 days/week, for 12 weeks.
Behavioral: Moderately intense exercise
Participants will receive oral metformin 500 mg twice daily for 12 weeks.
Drug: MetFORMIN 500 Mg Oral Tablet
Structured moderate-intensity aerobic activity (e.g., brisk walking) for 30-45 minutes/day, 5 days/week, for 12 weeks.
Also known as: Exercise Group
Participants will receive oral metformin 500 mg twice daily for 12 weeks.
Also known as: Metformin Group
Change in Glycated Hemoglobin (HbA1c) from Baseline to 12 Weeks
HbA1c (%) will be measured to assess glycemic improvement following 12 weeks of intervention.
Time frame: Baseline and 12 week
Weight change
Change in weight in kilograms from baseline to 12 weeks following the two interventions
Time frame: Baseline to 12 weeks
Plan to share: No — To maintain patients confidentiality
No publications or documents are linked to this record.
This study is completed, as verified in May 2026. You cannot join it, but the record below documents what was studied.
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Asad Ullah Jan