An observational study in Psoriatic Arthritis (PsA) and Subclinical Right Ventricular Systolic Dysfunction, sponsored by Ain Shams University. Not yet recruiting at 1 site in Egypt. Open to participants aged 20 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-07-01.
Sponsored by Ain Shams University · Observational
The aim is to assess early right ventricular systolic dysfunction in psoriatic arthritis patients using RV strain echocardiography
Previous studies evaluated RV strain for detection of subclinical RV affection due to PAH in systemic lupus erythematosus. However , to our knowledge , the study of RV strain and its possible association with serum endostatin to detect subclinical right ventricular systolic dysfunction and its relation to PAH in PsA patient is still a novel. Our aim is to assess early right ventricular systolic dysfunction in psoriatic arthritis patients using RV strain Echocardiography.
To evaluate serum endostatin as an objective biomarker for Pulmonary arterial hypertension.
579 studies on the registry are indexed under Arthritis, Psoriatic; 132 are open to participants now.
This study's planned enrollment of 60 is below the median of 300 across 235 observational studies indexed under Arthritis, Psoriatic.
Browse Arthritis, Psoriatic studies →Ain Shams University is the lead sponsor of 1,876 studies on the registry; 423 are open to participants now.
Of its 32 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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30 patients with PsA and 30 matched healthy controls
Exclusion Criteria:
30 control group matched as regards BMI, age and sex will be subjected to transthoracic echo and measuring serum endostatin level.
30 PsA patients will be subjected to transthoracic echo, measuring serum endostatin level and modified composite psoriatic disease activity index
Detecting subclinical right ventricular systolic dysfunction in PsA patients
Detecting subclinical right ventricular systolic dysfunction in PsA using 2D strain transthoracic echo and its relation to serum endostatin level
Time frame: Up to 24 months
Plan to share: Undecided
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This study is not yet recruiting, as verified in May 2025. You cannot join it, but the record below documents what was studied.
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Ain Shams University