ClinicalTrials.gg
Not yet recruitingNCT07017491Updated Jun 12, 2025

Determination of Glycemic Index and Glycemic Load of Selected Melon Varieties in Healthy Adults

An interventional study of Orange candy melon (Cucumis melo) and Rock melon ( Cucumis melo var.cantalupensis) in Glycemic Index and Glycemic Load, sponsored by Rehman Medical Institute - RMI. Not yet recruiting. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-06-12.

Sponsored by Rehman Medical Institute - RMI · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Primary completion was expected by Aug 2025, 1 year 3 months ago, but the record still lists the study as not yet recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
16
Allocation
Not applicable
Ages
18 Years to 50 Years
Sex
All
01

Study summary

This crossover study aims to determine and compare the glycemic index (GI) and glycemic load (GL) of different melon varieties in healthy adults. Using glucose as the reference food, participants will consume test portions of each melon variety containing equivalent amounts of available carbohydrates.

Read the detailed description

This crossover study aims to determine and compare the glycemic index (GI) and glycemic load (GL) of different melon varieties in healthy adults. Using glucose as the reference food, participants will consume test portions of each melon variety containing equivalent amounts of available carbohydrates. Blood glucose levels will be monitored at regular intervals over a 2-hour period. The glycemic response will be used to calculate GI and GL values for each melon type. The study is intended to inform dietary recommendations for blood glucose management.

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Conditions studied

  • Glycemic Index
  • Glycemic Load

Keywords

  • GLYCEMIC LOAD
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In context

Lead sponsor

Rehman Medical Institute - RMI is the lead sponsor of 24 studies on the registry; 10 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Healthy males and females aged 18-50 years. 2) (BMI) :Normal BMI (18-24.9) 3) Willingness to follow dietary instructions and attend all testing sessions

Exclusion criteria

  • Exclusion Criteria:

    1. Individuals with known metabolic disorders (e.g., diabetes, metabolic syndrome).
    2. Use of medications or supplements affecting blood glucose.
    3. Allergy or intolerance to melon or glucose solutions.
    4. Not able to co ordinate
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
16 participants (estimated)

Study arms

  • Experimental
    Single group (cross over)

    Participants will consume a glucose solution containing 50 grams of available carbohydrates. This will serve as the reference food to calculate the glycemic index (GI) of the test melons.

    Other: Orange candy melon (Cucumis melo) · Other: Rock melon ( Cucumis melo var.cantalupensis) · Other: honey dew (cucumis melo L.)

Interventions

  • OtherOrange candy melon (Cucumis melo)

    Participants will consume a portion of melon A containing 50g of available carbohydrates to evaluate postprandial glycemic response.

  • OtherRock melon ( Cucumis melo var.cantalupensis)

    Participants will consume a portion of melon B containing 50g of available carbohydrates to evaluate postprandial glycemic response.

  • Otherhoney dew (cucumis melo L.)

    Participants will consume a portion of melon C containing 50g of available carbohydrates to evaluate postprandial glycemic response.

06

What researchers measure

Primary outcomes

  1. Glycemic Index (GI) of Melon Varieties

    The glycemic index of each melon variety will be calculated by comparing the incremental area under the blood glucose response curve (iAUC) over 2 hours after consumption of the test food, relative to glucose.

    Time frame: 1 month

Secondary outcomes

  1. Glycemic Load (GL) of Melon Varieties

    Calculated using the formula: Glycemic Load = (Glycemic Index × amount of carbohydrate in a typical serving) ÷ 100

    Time frame: 1 month

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Study locations

No study locations are listed for this record.

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References and documents

Related links

Individual participant data

Plan to share: Undecided

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 12, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07017491
Lead sponsor
Rehman Medical Institute - RMI
Responsible party
Naseer Ahmed (Associate Professor, Rehman Medical Institute - RMI) — Principal investigator
First posted
Jun 12, 2025
Start date
Jun 2025 (estimated)
Primary completion
Aug 2025 (estimated)
Completion
Sep 2025 (estimated)
Last update
Jun 12, 2025

Study contacts

Naseer Ahmed
Contact
dr.naseer99@mail.com
03305485960

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in May 2025. You cannot join it, but the record below documents what was studied.

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Discussion

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