An interventional study of Temporal Interference in Essential Tremor, sponsored by Liankun_Ren. Recruiting at 1 site in China. Open to participants aged 30 Years to 70 Years. Per ClinicalTrials.gov, last updated 2025-07-16.
Sponsored by Liankun_Ren · Not applicable, Interventional, and Treatment
This single-center prospective study aims to investigate the treatment efficacy of temporal interference (TI) in essential tremor patients aged 30-70.
Temporal Interference (TI) technology is a novel non-invasive method for deep brain stimulation (DBS). By generating an overlapping electric field from safe currents, TI creates focused stimulation in targeted deep brain areas. This approach allows for the exploration of deep brain nuclei functions and has the potential to serve as a non-invasive alternative to traditional invasive DBS for clinical treatments.
This study aims to investigate the treatment efficacy of TI deep brain stimulation by including essential tremor patients aged 30-70. Before and after TI stimulation, clinical data will be recorded. Clinical and imaging data will be analyzed and processed to advance the treatment of essential tremor.
261 studies on the registry are indexed under Essential Tremor; 74 are open to participants now.
This study's planned enrollment of 10 is below the median of 24 across 185 interventional studies indexed under Essential Tremor.
Browse Essential Tremor studies →Liankun_Ren is the lead sponsor of 2 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
The investigators perform temporal interference (TI) stimulation to patients with essential tremor. They observe clinical manifestations before and after stimulation to investigate the efficiency of TI.
Other: Temporal Interference
Researchers apply temporal interference (TI) stimulation to the deep brain nuclei of essential tremor patients.
Tremor Level Evaluation
Percentage change in per month after stimulation from baseline in The Essential Tremor Rating Assessment Scale(TETRAS) score. The TETRAS score ranges from 0 to 112, including an activities of daily living (ADL) section(0-48 scores) and a performance section(0-64 scores), with higher scores representing more severe tremor and lower scores indicating lower tremor level
Time frame: Up to 3 months after TI stimulation
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