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Not yet recruitingNCT07008807Updated Jun 6, 2025

The Facial Muscular Activity: A Paradigm for Understanding Facial Asymmetry

An observational study in Facial Asymmetry, sponsored by South Valley University. Not yet recruiting at 1 site in Egypt. Open to participants aged 16 Years and older. Per ClinicalTrials.gov, last updated 2025-06-06.

Sponsored by South Valley University · Observational

From the registry’s dates

  • Primary completion was expected by Jul 2025, 1 year 4 months ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
100
Ages
16 Years and older
Sex
All
01

Study summary

Facial asymmetry, the degree to which the two sides of the face differ in size, shape, or the arrangement of features, is a near-universal human characteristic. The intricate network of facial muscles plays a crucial role in both the static structure and the dynamic expressions of the face. The continuous pull and action of facial muscles can influence the development and positioning of underlying soft tissues and even, over extended periods, potentially impact skeletal structures.

02

Conditions studied

  • Facial Asymmetry

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03

In context

Facial Asymmetry

27 studies on the registry are indexed under Facial Asymmetry; 10 are open to participants now.

This study's planned enrollment of 100 is above the median of 72 across 10 observational studies indexed under Facial Asymmetry.

Browse Facial Asymmetry studies →

Lead sponsor

South Valley University is the lead sponsor of 153 studies on the registry; 46 are open to participants now.

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Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
16 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Presenting with noticeable facial asymmetry.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Presenting with noticeable facial asymmetry
  • Age > 16 years
  • General good health
  • Absence of specific neurological conditions affecting facial muscles.
  • Absence of congenital facial disorders that might cause facial asymmetry, like hemifacial microsomia and cleft lip and palate syndromes.

Exclusion criteria

Exclusion Criteria:

  • History of facial trauma or surgery
  • Diagnosed Neuromuscular Disorders
  • Active facial infections.
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
100 participants (estimated)
Patient registry
No

Groups and cohorts

  • group A

    people with facial asymmetry

  • Group B

    control group of healthy normal people

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What researchers measure

Primary outcomes

  1. Facial Electromyography (EMG)

    Time frame: Day 1

  2. Facial Asymmetry Measurement

    assesses differences between the two sides of the face using various techniques, both two-dimensional (2D) and three-dimensional (3D)

    Time frame: Day 1

Secondary outcomes

  1. Demographic and Clinical Data

    Time frame: Day 1

07

Study locations

1 site
  • orthodontic outpatient clinic, and students at Faculty of Dentistry, Alsalam University, Egypt
    Tanta, Egypt
08

References and documents

Publications

  • 4. Kowner, R. (1996). Facial asymmetry and attractiveness judgment in Western and Japanese cultures. Journal of Social Behavior and Personality, 11(2), 301-314.
  • Ferrario VF, Dellavia C, Tartaglia GM, Turci M, Sforza C. Soft tissue facial morphology in obese adolescents: a three-dimensional noninvasive assessment. Angle Orthod. 2004 Feb;74(1):37-42. doi: 10.1043/0003-3219(2004)0742.0.CO;2. PubMed 15038489 ↗

Individual participant data

Plan to share: Undecided

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Jun 2025; primary completion for Jul 2025, 1 month later.

How these figures are worked out, and which studies are left out of them.

Registered
May 20, 2025
First posted
Jun 6, 2025
StartEst.
Jun 1, 2025
Primary completionEst.
Jul 1, 2025
CompletionEst.
Aug 1, 2025
Last update
Jun 6, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 6, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07008807
Lead sponsor
South Valley University
Responsible party
Mohammed E. Ali (Lecturer of Physical Therapy for surgery, South Valley University) — Principal investigator
First posted
Jun 6, 2025
Start date
Jun 1, 2025 (estimated)
Primary completion
Jul 1, 2025 (estimated)
Completion
Aug 1, 2025 (estimated)
Last update
Jun 6, 2025

Study contacts

Mohammed E. Ali, PhD
Contact
m.essam@svu.edu.eg
+201011212425
Nehad A. Abo-zaid, PhD
Contact

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in May 2025. You cannot join it, but the record below documents what was studied.

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Discussion

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