An observational study in Orthopaedic Injuries and Concussion (Diagnosis), sponsored by Texas Christian University. Active, not recruiting at 1 site in United States. Open to participants aged 17 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-06-05.
Sponsored by Texas Christian University · Observational
The overall objective of this study is to identify risk factors for two of the most common types of injuries in collegiate athletics - orthopedic injuries and concussion injuries.
Aim 1 of this study is to investigate risk factors for orthopedic injuries from a brief testing battery developed by the research team.
Aim 2 of this study is to investigate risk factors for concussion injuries and subsequent sequelae after returning to play from concussion from the same brief testing battery developed by the research team. Additionally, we will examine the relationships between orthopedic injuries and concussion injuries in the collegiate athlete.
Participants will participate in a pre-season battery of tests that include:
Further, retrospective chart reviews of past medical history and prospective injury tracking will be collected on all subjects.
The study involves a total of one to three visits, depending on whether an athlete sustains an injury. If an enrolled athlete does not sustain an injury during their athletic season, they will only complete visit 1. If they do, they will complete visits 1, 2, and 3. In total, the expected time requirement is less than 1 hour across the season.
This study will be a two year project in which athletes will be tested around the beginning of their respective sport season.
The PI or Co-I will ask the potential study participant questions regarding inclusion/exclusion criteria. If the potential participant meets all inclusion criteria and no exclusion criteria exist, then the informed consent process can begin. The PI or Co-I will review the informed consent document with the participant. If the participant agrees to be a part of the research study, then the informed consent and authorization form (HIPAA) will be signed electronically.
As part of the 1st Aim of the study: 1 visit, approximately 15 minutes
Information to be collected after consent but does not require the subject to be present:
Initial Pre-season visit (approximately 15 minutes)
All subjects will perform:
Initial pre-season testing should take approximately 15 minutes for actual testing with time requirement of no more than 30 minutes if completing testing in a group setting.
For athletes who sustain non-concussive injuries, standard of care rehab assessments will be collected over the course of recovery and at time of return to play by the treating physical therapist or athletic trainer. These standard of care measures utilized will be up to the rehabilitation provider in their practice and will not add time nor commitment from a research perspective for study participants but may be collected as data to describe injury and recovery characteristics.
As part of the 2nd Aim of the study: 2 additional visits, approximately 15 minutes each Subjects who sustain a concussion, will be identified, and diagnosed by a team physician. As part of the standard University Athletics protocol, these subjects will undergo repeat testing of the following, until they meet satisfactory baseline criteria that is decided upon by the treating physician and athletic trainer.
As part of the study protocol, these subjects will be asked to return for the following repeat testing:
2nd Visit - during week following concussive injury (approximately 15 minutes)
Only subjects that sustain a concussion will perform:
3rd Visit - at time of return to play following concussive injury (approximately 15 minutes)
Only subjects that sustain a concussion will perform:
For athletes who sustain a concussive and/or any non-concussive injuries, standard of care rehab assessments will be collected over the course of recovery and at time of return to play by treating physical therapist or athletic trainer. These standard of care measures utilized will be up to the rehabilitation provider in their practice and will not add time nor commitment from a research perspective for study participants but may be collected as data to describe injury and recovery characteristics.
530 studies on the registry are indexed under Brain Concussion; 151 are open to participants now.
This study's planned enrollment of 500 is above the median of 180 across 146 observational studies indexed under Brain Concussion.
Browse Brain Concussion studies →Texas Christian University is the lead sponsor of 33 studies on the registry; 6 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Incoming and current NCAA division I collegiate athletes at Texas Christian University
Exclusion Criteria:
All subjects must be current NCAA Division 1 collegiate level athletes at Texas Christian University. Subject testing will include: neurocognitive tests, balance tests, jump tests, strength tests.
Other: Exposed group
All subjects are tested pre-season for their sport. They are then prospectively followed for orthopaedic and/or concussive injury. If injuries occur, then repeat testing is performed.
Also known as: Exposure to Orthopaedic injury, Exposure to concussive injury
Movement Tests
Jumping, landing and balance tasks. Clinical analysis of double limb and single limb jumping, landing and balance on portable force plates. All physical movement and performance tests will be stopped if subject requests to stop or a significant risk of injury is identified. Tests will take approximately 10 minutes.
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Sway Neurocognitive Reaction Time Testing
Sway Sport mobile application assessment test: Reaction time (see explanation of study procedures for information on tests). All cognitive testing will be stopped if subject requests to stop. Tests will take approximately 5 minutes.
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Sway Neurocognitive Impulse Control Testing
Sway Sport mobile application assessment test: Impulse control (see explanation of study procedures for information on tests). All cognitive testing will be stopped if subject requests to stop. Tests will take approximately 5 minutes.
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Sway Neurocognitive Cued Stroop Testing
Sway Sport mobile application assessment test: Selective attention (see explanation of study procedures for information on tests). All cognitive testing will be stopped if subject requests to stop. Tests will take approximately 5 minutes.
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Concussion Prospective Injury C3 Logix
Subjects who sustain a concussion, will be identified, and diagnosed by a team physician. As part of the standard University Athletics protocol, these subjects will undergo repeat testing of the following, until they meet satisfactory baseline criteria that is decided upon by the treating physician and athletic trainer. 1. C3Logix neurocognitive testing (see explanation of study procedures for information on tests)
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Concussion Prospective Injury Tracking - Symptom Reporting
Subjects who sustain a concussion, will be identified, and diagnosed by a team physician. As part of the standard University Athletics protocol, these subjects will undergo repeat testing of the following, until they meet satisfactory baseline criteria that is decided upon by the treating physician and athletic trainer. Collected: 1. Subjective symptom reporting scale as designated by team physician
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Medical History Demographics
Participant Medical History collected includes: Demographic information from University Athletics athlete health tracking system.
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Medical History Current Injuries
Participant Medical History collected includes: Current injuries and characteristics from University Athletics athlete health tracking system and Pre-participation physical exam conducted by the University.
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Past Medical History Injuries
Participant Past Medical History collected includes: Past injuries and characteristics from University Athletics athlete health tracking system and Pre-participation physical exam conducted by the University.
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Medical History Medications
Participant Medical History collected includes: Current medications and supplements from University Athletics athlete health tracking system and Pre-participation physical exam conducted by the University.
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Prospective Injury Tracking - Type of Injury
Injury occurrence and characteristics during the yearlong season will be tracked and recorded by team athletic trainers and inputted into athlete health tracking system: Collected: Type of injury
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Prospective Injury Tracking - Location of Injury
Injury occurrence and characteristics during the yearlong season will be tracked and recorded by team athletic trainers and inputted into athlete health tracking system: Collected: Location of injury
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Prospective Injury Tracking - Mechanism of Injury
Injury occurrence and characteristics during the yearlong season will be tracked and recorded by team athletic trainers and inputted into athlete health tracking system: Collected: Mechanism of injury
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Prospective Injury Tracking - Severity of Injury
Injury occurrence and characteristics during the yearlong season will be tracked and recorded by team athletic trainers and inputted into athlete health tracking system: Collected: Severity of injury
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Prospective Injury Tracking - Time Missed
Injury occurrence and characteristics during the yearlong season will be tracked and recorded by team athletic trainers and inputted into athlete health tracking system: Collected: Time missed due to injury
Time frame: Baseline testing will occur within the two weeks prior to the start of a sport's season, follow up testing will occur if injury exposure occurs through the study completion (up to 5 years in college setting)
Plan to share: No
This study is active, not recruiting, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.
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