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Enrolling by invitationNCT07002775Updated Jun 4, 2025

Which Position Is Better For CPR In OHCA Patients?

An interventional study of Transesophageal ultrasound in Cardiac Arrest (CA), sponsored by National Taiwan University Hospital. Enrolling by invitation at 2 sites in Taiwan. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-06-04.

Sponsored by National Taiwan University Hospital · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jan 2026, 8 months ago, but the record still lists the study as enrolling by invitation.
  • Registered 3 months after the study started (first participant enrolled Jan 2025, registered May 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

Use Transesophageal ultrasound in OHCA patients to identify the proper CPR position

02

Conditions studied

  • Cardiac Arrest (CA)

Browse trials for

Keywords

  • OHCA
  • TEE
03

In context

Heart Arrest

965 studies on the registry are indexed under Heart Arrest; 225 are open to participants now.

This study's planned enrollment of 50 is below the median of 100 across 556 interventional studies indexed under Heart Arrest.

Browse Heart Arrest studies →

Lead sponsor

National Taiwan University Hospital is the lead sponsor of 2,563 studies on the registry; 568 are open to participants now.

Of its 12 completed or terminated interventional studies of FDA-regulated products, 2 (17%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Out of hospital cardiac arrest patients

Exclusion criteria

Exclusion Criteria:

  • DNR was signed,
  • Age under 18
  • Trauma patients
  • Patients hard to establish advanced airway
  • C spine injury patients
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
50 participants (estimated)

Study arms

  • Other
    CPR position

    Same patient with different CPR position : head up or supine

    Device: Transesophageal ultrasound

Interventions

  • DeviceTransesophageal ultrasound

    Transesophageal ultrasound with built-in ultrasound software (Philips QLAB 3D quantification advance, Philips Healthcare, USA, speckle tracking echocardiography (STE,Speckle tracking echocardiography) to evaluate stroke volume and cardiac output in different position with the same person

06

What researchers measure

Primary outcomes

  1. cardiac output

    built-in ultrasound software (Philips QLAB 3D quantification advance, Philips Healthcare, USA, speckle tracking echocardiography (STE,Speckle tracking echocardiography)

    Time frame: check cardiac output while CPR(Periprocedural)(after TEE insertion) in head up and supine position

  2. stroke volume

    built-in ultrasound software (Philips QLAB 3D quantification advance, Philips Healthcare,

    Time frame: check stroke volume while CPR(Periprocedural)(after TEE insertion) in head up and supine position

07

Study locations

2 sites
  • Chang Bing Show Chawan Memorial Hospital
    Changhua, Taiwan
  • National Taiwan University Hospital
    Taipei, Taiwan
08

References and documents

Publications

  • Moore JC, Salverda B, Lick M, Rojas-Salvador C, Segal N, Debaty G, Lurie KG. Controlled progressive elevation rather than an optimal angle maximizes cerebral perfusion pressure during head up CPR in a swine model of cardiac arrest. Resuscitation. 2020 May;150:23-28. doi: 10.1016/j.resuscitation.2020.02.023. Epub 2020 Feb 27. PubMed 32114071 ↗
  • Moore JC, Holley J, Segal N, Lick MC, Labarere J, Frascone RJ, Dodd KW, Robinson AE, Lick C, Klein L, Ashton A, McArthur A, Tsangaris A, Makaretz A, Makaretz M, Debaty G, Pepe PE, Lurie KG. Consistent head up cardiopulmonary resuscitation haemodynamics are observed across porcine and human cadaver translational models. Resuscitation. 2018 Nov;132:133-139. doi: 10.1016/j.resuscitation.2018.04.009. Epub 2018 Apr 24. PubMed 29702188 ↗
  • Kim T, Shin SD, Song KJ, Park YJ, Ryu HH, Debaty G, Lurie K, Hong KJ. The effect of resuscitation position on cerebral and coronary perfusion pressure during mechanical cardiopulmonary resuscitation in porcine cardiac arrest model. Resuscitation. 2017 Apr;113:101-107. doi: 10.1016/j.resuscitation.2017.02.008. Epub 2017 Feb 16. PubMed 28215591 ↗
  • Debaty G, Shin SD, Metzger A, Kim T, Ryu HH, Rees J, McKnite S, Matsuura T, Lick M, Yannopoulos D, Lurie K. Tilting for perfusion: head-up position during cardiopulmonary resuscitation improves brain flow in a porcine model of cardiac arrest. Resuscitation. 2015 Feb;87:38-43. doi: 10.1016/j.resuscitation.2014.11.019. Epub 2014 Nov 28. PubMed 25447353 ↗

Individual participant data

Plan to share: Yes — all collected IPD

Supporting information: Study protocol

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 4, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07002775
Lead sponsor
National Taiwan University Hospital
Collaborators
Chang Bing Show Chwan Memorial Hospital
Responsible party
Sponsor
First posted
Jun 4, 2025
Start date
Jan 23, 2025
Primary completion
Jan 23, 2026 (estimated)
Completion
Jan 23, 2027 (estimated)
Last update
Jun 4, 2025

Study contacts

WANCHING LIEN
study director · National Taiwan University Hospital

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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