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RecruitingNCT07002580Updated Feb 6, 2026

Evaluation of the Effectiveness of iPACK and Adductor Canal Blocks on Patients Undergoing Arthroscopic Knee Surgery

An interventional study of IPACK and adductor canal block with Bupivacaine 0.25% and Spinal Anesthesia with Bupivacaine in Patients Undergoing Arthroscopic Knee Surgery, sponsored by Sakarya University. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2026-02-06.

Sponsored by Sakarya University · Not applicable, Interventional, and Supportive care

From the registry’s dates

  • Started Jul 2025; still recruiting 1 year 3 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
64
Allocation
Randomized
Ages
18 Years to 50 Years
Sex
All
01

Study summary

Arthroscopic knee surgery is one of the most commonly performed procedures in orthopedic surgery. More than 50% of patients experience moderate to severe pain after the operation. Inadequate postoperative pain control and poor recovery quality can negatively impact physiotherapy protocols, prolong hospital stays, and consequently lead to cognitive dysfunction, systemic infections, and increased healthcare costs.

Therefore, reducing postoperative pain and improving recovery quality are of great importance. In our clinic, a variety of analgesic techniques are routinely employed as part of a multimodal analgesia approach for patients undergoing arthroscopic knee surgery. One of these techniques is the simultaneous application of the IPACK block and the adductor canal block.

In this study, we aim to evaluate the effectiveness of these blocks on postoperative recovery quality in patients undergoing arthroscopic knee surgery.

02

Conditions studied

  • Patients Undergoing Arthroscopic Knee Surgery

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Keywords

  • Arthroscopic Knee Surgery
  • Perifheric Nerve Block
  • Analgesia
  • iPACK
  • Adductor Canal Block
  • QoR-15
03

In context

Agnosia

1,190 studies on the registry are indexed under Agnosia; 508 are open to participants now.

This study's planned enrollment of 64 is below the median of 78 across 1,024 interventional studies indexed under Agnosia.

Browse Agnosia studies →

Lead sponsor

Sakarya University is the lead sponsor of 178 studies on the registry; 48 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients aged between 18 and 50 years,
  • Scheduled for arthroscopic knee surgery under spinal anesthesia due to knee pathology
  • Patients classified as ASA physical status I-II-III according to the American Society of Anesthesiologists risk classification

Exclusion criteria

Exclusion Criteria:

  • Coagulopathy
  • ASA IV-V patients
  • Uncooperable patients
  • Patients who refuses to participate in study
  • Patients who takes chronic pain treatments
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
64 participants (estimated)

Study arms

  • Experimental
    Group 1

    Group 1 will involve the patients which will be applied iPACK and adductor canal blocks in addition to spinal anesthesia.

    Procedure: IPACK and adductor canal block with Bupivacaine 0.25% · Procedure: Spinal Anesthesia with Bupivacaine

  • Experimental
    Group 2

    Group 2 will involve the patients which will be applied only spinal anesthesia without additional peripheric nerve blocks.

    Procedure: Spinal Anesthesia with Bupivacaine

Interventions

  • ProcedureIPACK and adductor canal block with Bupivacaine 0.25%

    iPACK block is infiltration between the Popliteal Artery and the Capsule of the Knee. iPACK and adductor canal blocks are performed with ultrasound guidence under sterile conditions.

  • ProcedureSpinal Anesthesia with Bupivacaine

    Spinal Anesthesia is a basic anesthesia method used for years to grant anesthesia for surgeries for lower extremities and lower torso surgeries.

06

What researchers measure

Primary outcomes

  1. Quality of Recovery

    Quality of Recovery of the patients will be assessed with QoR-15 questionnaire. Its scoring will range between 0 and 150 points.

    Time frame: 24 hours.

Secondary outcomes

  1. Analgesic Consumption

    The total analgesic consumption of patients according to the patient controlled analgesia device which measures the opioid consumption for 24 hours.

    Time frame: 24 hours.

07

Study locations

1 of 1 sites recruiting
  • Sakarya University Training and Research Hospital
    Sakarya, Turkey (Türkiye)
    Recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 6, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07002580
Lead sponsor
Sakarya University
Responsible party
Oguzhan Okumus (Resident M.D., Sakarya University) — Principal investigator
First posted
Jun 3, 2025
Start date
Jul 1, 2025
Primary completion
Jan 1, 2026
Completion
Apr 1, 2026 (estimated)
Last update
Feb 6, 2026

Study contacts

Oğuzhan Okumuş, M.D.
Contact
dr.oguzhanokumusss@gmail.com
+905372093019

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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