An interventional study of Health education in Dengue and Infection Prevention, sponsored by Sun Yat-sen University. Not yet recruiting. Open to participants aged 6 Years to 15 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-06-03.
Sponsored by Sun Yat-sen University · Not applicable, Interventional, and Health services research
The goal of this cluster randomized controlled trial is to evaluate the effect of health education interventions on the score of the knowledge, attitudes, and practices (KAP) of dengue in in primary and middle school students in the city of Guangzhou and Foshan in China.
Individuals aged 6 to 15 years who are in grades 1-9 in primary schools in Guangzhou and Foshan will be enrolled. 20 primary schools will be randomly selected, with half designated as intervention group schools and the remaining half as control group schools. The intervention group will receive a health education intervention focused on dengue prevention every semester for 6 months, while the control group will continue with their routine school health education for 6 months.
Researchers will compare the differences in the score of the KAP of dengue between the intervention and control groups after 6 months to see if health education can improve knowledge, attitudes and practices of dengue among primary and middle school students.
Introduction: Dengue is one of the fastest spreading mosquito-borne infectious diseases in the world. Guangdong, as the core epidemic area of dengue fever in China, has experienced many large outbreaks of dengue in history due to its warm and humid climate, dense urbanization, and frequent communication with Southeast Asia. However, prevention and control measures in schools remains suboptimal. This study aims to improve the knowledge, attitudes, and practices (KAP) of dengue prevention and control among students, and reduce the density of mosquito vectors and the risk of dengue transmission in primary and middle schools.
Methods and analysis: This cluster randomized controlled trial will enroll 3940 students from 20 primary and middle schools in Guangzhou and Foshan City, China. Schools will be randomized to an intervention group receiving dengue health education and environmental governance or a control group receiving routine health education. The primary outcome is scores of KAP of students. Secondary outcomes include environmental mosquito vector index. Data will be collected through questionnaires, campus environment inspection, and self-reports at baseline and study conclusion.
Ethics and dissemination: Ethical approval has been sought from the Ethics Committee of the School of Public Health, Sun Yat-sen University. Findings from the study will be made accessible to key stakeholders.
283 studies on the registry are indexed under Dengue; 44 are open to participants now.
This study's planned enrollment of 3,940 is above the median of 132 across 197 interventional studies indexed under Dengue.
Browse Dengue studies →Sun Yat-sen University is the lead sponsor of 1,690 studies on the registry; 619 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
The intervention group will receive a health education intervention focused on dengue prevention every semester for 6 months
Combination Product: Health education
The control group will continue with their routine school health education for 6 months.
The intervention group will receive a health education intervention focused on dengue prevention and campus environmental governance, while the control group will continue with their standard school health education without any additional intervention. An health education including the knowledge of dengue fever, harm of mosquitoes, and measures of mosquito control, will be developed and reviewed by an expert group. The campus environmental governance includes organizing campus environmental cleaning once a week, focusing on removing mosquito breeding places such as water containers.
scores of the knowledge, attitudes, and practices (KAP) of dengue
Regarding the knowledge, attitudes, and practices of dengue, each correct answer for the health literacy research questionnaire will be scored as one point, with incorrect answers receiving no points.
Time frame: From enrollment to the end of intervention in 6 months
mosquito vector index
The mosquito vector index will be calculated as the number of mosquitoes captured in a fixed area divided by the total area.
Time frame: From enrollment to the end of intervention in 6 months
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Jun 2025; primary completion for Jun 2026, 11 months later.
Of 25 non-industry interventional studies with no phase under Dengue, half reached primary completion within 12 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 27. This study's planned 11 months is close to that.
Counting every sponsor, half of 30 studies reached it within 12 months; a quarter within 6 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in May 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.