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Not yet recruitingNCT06998082Updated May 31, 2025

AI-Driven Early Warning System for Perioperative Risks in Acute Hemorrhagic Stroke

An observational study in Acute Hemorrhagic Stroke, sponsored by Beijing Tiantan Hospital. Not yet recruiting at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2025-05-31.

Sponsored by Beijing Tiantan Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
1,533
Ages
18 Years to 80 Years
Sex
All
01

Study summary

Acute hemorrhagic cerebrovascular disease is a life-threatening condition characterized by sudden onset, rapid progression, multiple complications, poor prognosis, and high mortality. It presents a significant public health burden. During surgical interventions, precise risk stratification and effective perioperative management are crucial to mitigating intraoperative and postoperative complications, optimizing disease diagnosis, guiding severity assessment, and refining anesthesia strategies. Continuous real-time evaluation and dynamic perioperative adjustments are essential to minimize the influence of institutional variability and individual clinician-dependent decision-making. By harnessing big data-driven, evidence-based medical approaches, clinicians can enhance diagnostic accuracy and therapeutic precision, addressing a critical challenge in reducing morbidity and mortality in this patient population.

This study aims to develop a comprehensive multimodal perioperative database and leverage large language models (LLMs) for the efficient extraction of structured demographic and clinical data throughout the perioperative course. By integrating real-time hemodynamic monitoring parameters, the investigators seek to elucidate the relationship between perioperative hemodynamic patterns and the incidence of postoperative complications affecting major organ systems, including the brain, heart, kidneys, and lungs. The ultimate goal is to construct a multimodal fusion early-warning model capable of real-time, simultaneous prediction of multiple perioperative complications. This AI-driven platform will function as a risk stratification and alert system for organ-specific perioperative complications in patients with acute hemorrhagic cerebrovascular disease. By providing evidence-based insights for optimized perioperative management-encompassing early warning mechanisms, diagnostic support, and individualized therapeutic strategies-the system aims to improve clinical outcomes, reduce perioperative morbidity, and lower overall mortality.

02

Conditions studied

  • Acute Hemorrhagic Stroke

Keywords

  • Perioperative Complications
  • Artificial intelligence in Medicine
  • Acute hemorrhagic stroke
03

In context

Lead sponsor

Beijing Tiantan Hospital is the lead sponsor of 483 studies on the registry; 289 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The investigators plan to recruit patients aged 18-80 years with acute hemorrhagic cerebrovascular disease from a minimum of three tertiary Grade A general hospitals.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients aged 18 to 80 years.
  • Diagnosis confirmed by preoperative imaging (CT or MRI) of one of the following conditions:
  • Intracranial aneurysm
  • Arteriovenous malformation (AVM)
  • Hemorrhagic moyamoya disease
  • Cavernous malformation
  • Spontaneous intracerebral hemorrhage
  • Undergoing surgery within seven days of symptom onset.

Exclusion criteria

Exclusion Criteria:

  • Patients who decline to provide informed consent.
  • Patients enrolled in conflicting clinical studies.
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
1,533 participants (estimated)
Target follow-up
3 Months
Patient registry
Yes

Groups and cohorts

  • Patients with acute hemorrhagic cerebrovascular disease
06

What researchers measure

Primary outcomes

  1. The primary outcome measures were postoperative complications involving the neurological, cardiac, pulmonary, and renal systems in patients with acute hemorrhagic cerebrovascular disease following surgical interventions.

    Time frame: Within 30 days after surgery

07

Study locations

1 site
  • Beijing Tiantan Hospital
    Beijing, Beijing Municipality 100070, China
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Jul 2025; primary completion for Dec 2027, 29 months later.

How these figures are worked out, and which studies are left out of them.

Registered
May 9, 2025
First posted
May 31, 2025
StartEst.
Jul 6, 2025
Primary completionEst.
Dec 31, 2027
CompletionEst.
Dec 31, 2028
Last update
May 31, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on May 31, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06998082
Responsible party
Yuming Peng (Deputy chief of Department of Anesthesiology, Beijing Tiantan Hospital) — Principal investigator
First posted
May 31, 2025
Start date
Jul 6, 2025 (estimated)
Primary completion
Dec 31, 2027 (estimated)
Completion
Dec 31, 2028 (estimated)
Last update
May 31, 2025

Study contacts

ming yu Peng, M.D, Ph.D
Contact
florapym766@163.com
86-010-59976658

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.

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