ClinicalTrials.gg
CompletedNCT06976385Updated May 16, 2025

Clinical Impact of White Tea and Wheat Grass on Color Enhancement of White Spot Lesions

An interventional study of White tea and Wheat grass solution in White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, sponsored by Al-Azhar University. Completed at 1 site in Egypt. Open to participants aged 15 Years to 18 Years. Per ClinicalTrials.gov, last updated 2025-05-16.

Sponsored by Al-Azhar University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 6 months after the study started (first participant enrolled Oct 2023, registered May 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
12
Allocation
Randomized
Ages
15 Years to 18 Years
Sex
All
01

Study summary

The current study aimed to evaluate the color change potential of wheat grass and white tea on post orthodontic white spot lesions (WSLs). Materials and Methods: A total of 12 patients were divided into two main groups A1 and A2 according to type of treatment agent (n=6). The A1 group used 10% white tea solution while the A2 group used 10% wheat grass solution. Shade evaluation was conducted using VITA Easyshade V spectrophotometer. Baseline L a b values of WSLs were detected right after orthodontic bracket removal. Patients were requested to rinse with the treatment agent for 1 minute, twice per day. The mean L,a,b values were recorded after 1 month and after 3 months . ΔE values were calculated between baseline, 1 month and 3 months after the treatment agent application and subjected to statistical analysis using one way ANOVA with p>0.05. Also, Standardized photographs were taken at baseline, after 1 and 3 months. Each WSL was photographed twice with the 1st photograph taken of wet teeth and the 2nd one after prolonged air-drying in order to perform ICDAS II scoring.

02

Conditions studied

  • White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
03

In context

Lead sponsor

Al-Azhar University is the lead sponsor of 525 studies on the registry; 171 are open to participants now.

Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
15 Years to 18 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Age range between 15-18 years.
  2. Good oral hygiene
  3. Obvious area of WSL was found around the fixed orthodontic brackets.
  4. Included teeth should be free of any restorations

Exclusion criteria

Exclusion Criteria:

- : 1. Cavitated enamel surface. 2. Presence of any restorations including the labial surface of the involved teeth.

3. Presence of any environmental or developmental enamel defect such as enamel hypoplasia, fluorosis, stains, and trauma sites on teeth before orthodontic treatment. 4. Allergy to tea and/or wheat

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
12 participants (actual)

Study arms

  • Experimental
    White tea

    Participants prepared white tea mouth rinse to rinse thoroughly . At each rinsing, 10 mL of the solution was swished around the mouth for about 60 s and then spited This procedure was performed twice per day for 1 , and 3 months

    Dietary Supplement: White tea

  • Experimental
    Wheat grass solution

    Participants prepared wheat grass solution mouth rinse to rinse thoroughly . At each rinsing, 10 mL of the solution was swished around the mouth for about 60 s and then spited This procedure was performed twice per day for 1 , and 3 months

    Dietary Supplement: Wheat grass solution

Interventions

  • Dietary supplementWhite tea

    White tea mouth rinse applied topically twice daily.

  • Dietary supplementWheat grass solution

    wheat grass solution mouth rinse applied topically twice daily.

06

What researchers measure

Primary outcomes

  1. ΔE values were calculated

    The mean L,a,b values were recorded . ΔE values were calculated

    Time frame: after 1 month and after 3 months

07

Study locations

1 site
  • Al Azhar University
    Cairo, Egypt
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Oct 2023 to primary completion in Dec 2023, 2 months.

How these figures are worked out, and which studies are left out of them.

Registered
May 9, 2025
First posted
May 16, 2025
StartActual
Oct 15, 2023
Primary completionActual
Dec 15, 2023
CompletionActual
Dec 15, 2023
Last update
May 16, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on May 16, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06976385
Responsible party
Mariam Mohamed Taha Elnems (Lecturer of conservative dentistry, NewGiza University) — Principal investigator
First posted
May 16, 2025
Start date
Oct 15, 2023
Primary completion
Dec 15, 2023
Completion
Dec 15, 2023
Last update
May 16, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2025. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion