An observational study in Advanced Cancer, Terminal Malignant Tumors and Hospices, sponsored by National Taiwan University Hospital. Not yet recruiting. Per ClinicalTrials.gov, last updated 2025-05-08.
Sponsored by National Taiwan University Hospital · Observational
[Background] Nurses' roles in survival prediction and prognostic communication have historically been limited due to role delineation, lack of formal training, and cultural norms. In Taiwan and other cultural contexts, prognostic discussions have traditionally been the purview of physicians. However, evolving paradigms in health communication, practical realities in nursing practice, and the expanded responsibilities of advanced practice nurses have highlighted the importance of nurses in this domain. Nurses frequently engage in "foreseeing" prognostic indicators through daily patient care, and emerging evidence suggests their prognostic accuracy is often comparable to or exceeds that of physicians. Despite this, the exact scope of nurses' roles in prognostication remains unclear, creating gaps in understanding the contributions, benefits, and associating factors of nurses' involvement of prognostication process.
[Aim] This mixed-methods study aims to examine hospice nurses' competencies and roles in prognostication, with a focus on their survival prediction accuracy, confidence, influencing factors, and self-perceived responsibilities.
[Method] This three-year, cross-national study adopts an explanatory sequential mixed-methods design. First, the quantitative phase utilizes a prospective cohort design, recruiting palliative nurses and physicians from ten palliative care sites across three countries. Eligible clinicians include nurses and physicians who provide care for patients with advanced cancer in palliative care settings or oncologic wards. Participating clinicians will provide weekly prognostic predictions for targeted patients and rate their confidence levels. Patients' demographic and disease-related information will also be collected to estimate survival using prediction tools. Data collection will conclude upon the patient's death or discharge. Based on the results of the quantitative phase, a descriptive qualitative study will be conducted to purposefully recruit nurses with varying levels of prediction accuracy and confidence from the quantitative phase. Semi-structured interviews will be carried out to gather qualitative data on their perspectives regarding prognostication, with a particular focus on their roles. The estimated sample size for quantitative phase is 152 nurse-physician dyads (based on 152 patients), while 20-30 nurses are expected to participate in the qualitative phase.
[Data Analysis] Descriptive statistics, area under the receiver operating characteristic (ROC) curve (AUC), Cohen's kappa, weighted kappa, McNemar's test, and ordinal logistic regression will be used to analyze quantitative data. Qualitative data will be analyzed using conventional content analysis. Nurses' Competence and Role in Survival Prediction and Prognostic Communication.
[Expecting Outcomes and Conclusion] This project uniquely highlights nurses' contributions to prognostication, aiming to generate evidence that informs future research, clinical practice, and policy development. The findings will shed light on nurses' roles, functions, potential benefits, and the barriers the face in prognostication.
9,365 studies on the registry are indexed under Neoplasms; 2,489 are open to participants now.
This study's planned enrollment of 152 is below the median of 204 across 1,683 observational studies indexed under Neoplasms.
Browse Neoplasms studies →National Taiwan University Hospital is the lead sponsor of 2,563 studies on the registry; 569 are open to participants now.
Of its 11 completed or terminated interventional studies of FDA-regulated products, 2 (18%) have results posted.
Counted across the registry records on this site, refreshed daily.
The research team at each site will identify eligible patients in the palliative and hospice unit and invite their physicians and nurses to participate the study.
[Inclusion criteria for patients]
[Inclusion criteria for clinicians]
Exclusion Criteria:
Palliative nurses' accuracy in making survival prediction
The results of predicted survival time estimated by participants should be specified within a range of days to weeks. The accuracy will be measured by comparing their results of prediction to: (1) the patients actual survival, (2) those of physicians, and (3) survival prediction derived from prognostic tools.
Time frame: From enrollment to the end of treatment at 2.5 years
Palliative nurses' levels of confidence in making prognostic predictions
The level of confidence will be measured on the scale of 0 to 10.
Time frame: From enrollment to the end of treatment at 2.5 years
Relationship between palliative nurses' demographic variables, prognostic confidence, and survival prediction accuracy
Analysis of the association between nurses' demographic factors (e.g., age, years of experience, ward type) and their level of prognostic confidence and accuracy in predicting survival time for terminal cancer patients. Measured using structured questionnaires and comparison with actual survival outcomes.
Time frame: From enrollment to the end of treatment at 2.5 years
Palliative nurses' perceptions of their roles in prognostic prediction
Thematic analysis of interview transcripts to explore how nurses describe their roles in prognostic prediction
Time frame: From enrollment to the end of treatment at 2.5 years
Themes which affect palliative nurses' prognostic prediction and level of confidence
Identification and thematic analysis of key factors influencing palliative care nurses' prognostic predictions and their level of confidence. Themes will be derived from qualitative data collected through semi-structured and analyzed using content or thematic analysis.
Time frame: From enrollment to the end of treatment at 2.5 years
No study locations are listed for this record.
This study is not yet recruiting, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.
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National Taiwan University Hospital