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Active, not recruitingNCT06960915ReminiSOMMEUpdated Feb 11, 2026

Efficacy of Virtual Reality Reminiscence Therapy in Nursing Home Residents With Alzheimer's Disease or Related Diseases

An interventional study of immersive virtual reality and classic reminiscence workshops in Virtual Reality, Reminiscence Therapy and Nursing Home, sponsored by Centre Hospitalier Universitaire, Amiens. Active, not recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-11.

Sponsored by Centre Hospitalier Universitaire, Amiens · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

This project provides the easiest possible access to heritage elements that older persons with Alzheimer's disease or related diseases knew well but to which they no longer have access due to the motor and functional dependencies they present. It will strengthen the possibilities of reminiscence by using, rather than the usual supports, virtual reality technology to reinforce the immersion effect. It will involve carrying out virtual reality reminiscence workshops intended for residents in nursing home with Alzheimer's disease or related diseases and allowing them to explore the heritage of towns and villages in the Somme region thanks to these innovative solutions. The aim of this project is to reduce behavioral disorders and improve their quality of life.

02

Conditions studied

  • Virtual Reality
  • Reminiscence Therapy
  • Nursing Home
  • Alzheimer's Disease or Related Diseases
  • Crossover Study

Keywords

  • Virtual reality
  • Reminiscence therapy
  • Nursing home
  • Alzheimer's disease or related diseases
  • crossover study
03

In context

Lead sponsor

Centre Hospitalier Universitaire, Amiens is the lead sponsor of 576 studies on the registry; 178 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Residents of the long-term care facilities of the Amiens-Picardie University Hospital,
  • Residents with mild to moderate Alzheimer's disease or related diseases, i.e. with an MMSE ≥ 10,
  • Residents or their legal representative agreeing to participate in the study.

Exclusion criteria

Exclusion Criteria:

  • Non-residents of the long-term care facilities of the Amiens-Picardie University Hospital,
  • Residents with an MMS \< 10,
  • Residents or their legal representative refusing to participate in the study,
  • Residents in terminal palliative care,
  • Residents with disruptive behavioral disorders.
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
50 participants (estimated)

Study arms

  • Experimental
    immersive virtual reality

    The residents will be equipped with a virtual reality headset where they will enjoy 360° panoramas that will immerse them in the heart of villages in the Amiens basin and in particular their village based on 3 to 5 images per village: church square, village square, town hall, emblematic places, etc

    Device: immersive virtual reality

  • Active comparator
    classic reminiscence workshops

    classic reminiscence workshops in which the organizer will propose to discuss memories and past experiences using photographs, objects or music in the control arm

    Device: classic reminiscence workshops

Interventions

  • Deviceimmersive virtual reality

    The research procedure will be the realization of reminiscence workshops in immersive virtual reality. The residents will be equipped with a virtual reality headset where they will enjoy 360° panoramas that will immerse them in the heart of villages in the Amiens basin and in particular their village based on 3 to 5 images per village: church square, village square, town hall, emblematic places, etc.

  • Deviceclassic reminiscence workshops

    It will be compared to classic reminiscence workshops in which the organizer will propose to discuss memories and past experiences using photographs, objects or music in the control arm.

06

What researchers measure

Primary outcomes

  1. Reduced behavioral problem frequency in immersive virtual reality group

    Efficacy in reducing behavioral problems will be assessed using the sum of scores on the NPI-ES anxiety, depression, and apathy subscales.

    Time frame: 1 year

Secondary outcomes

  1. Improved quality of life in the immersive virtual reality group

    improving the quality of life will be assessed using a quality of life scale developed for patients with Alzheimer's disease or related diseases, the QOL-AD scale validated in French. The QOL-AD is administered in interview format to individuals with dementia, following the instructions below. Scoring instructions for QOL-AD: Points are assigned to each item as follows: poor = 1, fair = 2, good = 3, excellent = 4. The total score is the sum of all 13 items.

    Time frame: 1 year

07

Study locations

1 site
  • CHRU Amiens
    Amiens, 80480, France
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 11, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06960915
Lead sponsor
Centre Hospitalier Universitaire, Amiens
Responsible party
Sponsor
First posted
May 7, 2025
Start date
Oct 10, 2025
Primary completion
Nov 2026 (estimated)
Completion
Mar 2027 (estimated)
Last update
Feb 11, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.

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