ClinicalTrials.gg
RecruitingNCT06954194Updated May 4, 2025

Syntactic Intervention for Cantonese-speaking Children With DLD

An interventional study of Explicit intervention (Shape Coding+syntactic priming) and Implicit intervention (syntactic priming only) in Developmental Language Disorder, sponsored by The Hong Kong Polytechnic University. Recruiting at 1 site in Hong Kong. Open to participants aged 5 Years to 8 Years. Per ClinicalTrials.gov, last updated 2025-05-04.

Sponsored by The Hong Kong Polytechnic University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by May 2026, 6 months ago, but the record still lists the study as recruiting.
  • Registered 1 year 2 months after the study started (first participant enrolled Feb 2024, registered Apr 2025).
  • Started Feb 2024; still recruiting 2 years 9 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
32
Allocation
Randomized
Ages
5 Years to 8 Years
Sex
All
01

Study summary

The goal of this clinical trial is to compare the efficacy of explicit vs. implicit intervention on subject relative clause production in Cantonese-speaking children with Developmental Language Disorder (DLD). It will also learn about individual difference predictors of intervention outcomes. The main questions it aims to answer are:

  1. Will the explicit intervention (Shape Coding+syntactic priming) on relative clause production lead to better outcomes than implicit intervention (syntactic priming only)?
  2. Can pre-intervention procedural learning, working memory (WM) capacities, and grammar impairment severity predict the intervention outcomes across children with DLD?
  3. Will 10 intervention sessions (500 doses of the target structure) lead to learning progress in children with DLD, even with implicit intervention, and will the progress plateau at some point of the intervention?

Researchers will compare the explicit intervention to the implicit intervention to see if the explicit intervention leads to better interventional outcomes.

Participants will:

  • Undergo diagnostic assessments of DLD to confirm their DLD status.
  • Complete pre-intervention assessments to assess their procedural learning and working memory capacities.
  • Undergo the intervention phase, which consists of a pretest, 10 intervention sessions, three posttests (after the 1st, 5th and 10th intervention), and a retention test (1 month after the last intervention).
Read the detailed description

This project is the first to adopt a randomized controlled trial (RCT) to compare the efficacy of explicit vs. implicit intervention on relative clause production (subject relative clause in object position of the main clause or SRC-O) in Cantonese-speaking children with DLD and to use an individual difference approach to identify predictors of intervention outcomes.

The investigators aim to examine the following three specific questions:

  1. Will the explicit intervention (Shape Coding+syntactic priming) on relative clause production lead to better outcomes than implicit intervention (syntactic priming only)? Based on the Procedural circuit Deficit Hypothesis (PDH), the investigators hypothesize that explicit intervention would switch the reliance of learning to the relatively intact declarative learning circuitry and lead to better outcomes than implicit intervention.
  2. Can pre-intervention procedural learning, working memory (WM) capacities, and grammar impairment severity predict the intervention outcomes across children with DLD? Based on the PDH, the investigators hypothesize that children with lower procedural learning abilities will demonstrate worse outcomes in the implicit intervention group, but better outcomes in the explicit intervention group. As for WM and grammar impairment, the investigators hypothesize that children with better WM or grammatical abilities will demonstrate better outcomes in both groups.
  3. Will 10 intervention sessions (500 doses of the target structure) lead to learning progress in children with DLD, even with implicit intervention, and will the progress plateau at some point of the intervention? As informed by previous studies, the investigators hypothesize that more exposure to the target structure, especially with high variability in the input, will lead to improvement, even for the implicit intervention group. The investigators will explore whether the progress will plateau over the course of interventions and compare the learning trajectory between explicit and implicit interventions.

A total of 32 Cantonese-speaking school-age children with DLD (5-8 years old) will be recruited (N=16/group). The children will be pre-screened with an online questionnaire on language background and case history, and then assessed on the Raven's Standard Progressive Matrices (\~25 min), hearing screening (\~5 min) and Hong Kong Cantonese Oral Language Assessment Scale (HKCOLAS) (\~90 min) to confirm DLD. Eligible children will be assigned to one of the two intervention groups following a random allocation sequence of letters "A" and "B" (e.g., ABBBA...), where A and B refer to the explicit and implicit intervention respectively, on a 1:1 allocation ratio.

The study consists of pre-intervention assessments and an intervention phase. For pre-intervention assessments, children's procedural learning, declarative learning, and working memory capacities will be assessed using the serial reaction time (SRT) task, old/new picture recognition task, and forward and backward digit span test, respectively. The purpose is to examine the predictive power of these capacities in the individual children's intervention outcomes.

The intervention phase includes a pretest, 10 intervention sessions, three posttests (after the 1st, 5th and 10th intervention), and a retention test (1 month after the last intervention). The pretest serves as a baseline; the three posttests are to assess maintenance of the target structure (SRC-O) after priming has ceased and the improvement over the course of interventions; the retention test is for assessing longer-term retention of the intervention outcomes.

The procedure of the pretest, three posttests and retention (\~10 min/test) is identical, during which the children will be asked to describe 10 pictures without priming or feedback from the experimenter. Ten online intervention sessions (\~45 min/session) will be administered to the children via zoom over four weeks, with 2-3 sessions per week.

For explicit intervention, a syntactic priming task will be preceded by explicit teaching of the target structure using the Shape Coding scheme adapted to be age- and language (Cantonese)-appropriate. A different set of 10 sentences will be used for teaching in each explicit intervention session, with five sentences used as exemplars for the experimenter to explain the target structure, and the remaining five sentences for children to practice. During the practice, the children will be asked to drag words into their corresponding shapes (e.g., oval for noun/noun phrase, rhombus for verb/verb phrase, and square for particle). All sentences will be constructed using the P1 Chinese character database to ensure that children can read the sentences.

The syntactic priming session will be presented as a game to sustain the children's interest and to disguise the purpose of the study. Each intervention session will contain 40 pairs of prime-target pictures, 40 pairs of control-target pictures, and 20 pairs of filler pictures, randomly presented to the experimenter and child and controlled by the experimenter. The game rule is to catch when two identical pictures are presented to the experimenter and child (i.e., fillers) by saying "Snap!". For each prime/control-target pair, the experimenter will describe a picture using the target structure - subject relative clause in object position of the main clause (SRC-O), and the child will produce a sentence based on the second picture. In total, there are 500 doses of SRC-O sentences (50 sentences x10 sessions).

For implicit intervention, the same 10 sessions of syntactic priming will be provided to the children without explicit instruction of the SRC-O structure using the Shape Coding System. Nonetheless, to make the exposure and dosage as comparable as possible between the two groups, children in the implicit intervention group will also receive 10 listening sessions before the syntactic priming sessions. During the listening sessions, the same sets of sentences used in the explicit instruction sessions will be presented and the children will be instructed to listen closely as the tutor reads aloud the SRC-O sentence. Each listening session will be followed by a syntactic priming session that is identical to that of the explicit intervention group. In total, there are also 500 doses of SRC-O sentences (50 sentences x10 sessions).

02

Conditions studied

  • Developmental Language Disorder

Keywords

  • Randomized Controlled Trial
  • Explicit intervention
  • Implicit intervention
  • Procedural circuit Deficit Hypothesis
  • Individual difference
  • Relative clause
  • Syntactic priming
  • Shape coding
03

In context

Language Development Disorders

121 studies on the registry are indexed under Language Development Disorders; 49 are open to participants now.

This study's planned enrollment of 32 is below the median of 74 across 106 interventional studies indexed under Language Development Disorders.

Browse Language Development Disorders studies →

Lead sponsor

The Hong Kong Polytechnic University is the lead sponsor of 679 studies on the registry; 257 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
5 Years to 8 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • being Cantonese dominant who learned Cantonese as their first language and attending Cantonese-medium primary schools.
  • having normal IQ and no hearing impairment.
  • scoring at least -1.25 SD below the mean in any two subtests of the Hong Kong Cantonese Oral Language Assessment Scale (a standardized language assessment tool for Hong Kong Cantonese-speaking children).

Exclusion criteria

Exclusion Criteria:

  • Autism Spectrum Disorder.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
32 participants (estimated)

Study arms

  • Experimental
    Explicit intervention group

    Participants in this group will receive explicit teaching of the target structure using the Shape Coding scheme adapted to be age- and language (Cantonese)-appropriate, followed by syntactic priming sessions.

    Behavioral: Explicit intervention (Shape Coding+syntactic priming)

  • Active comparator
    Implicit intervention group

    Participants in this arm will receive identical syntactic priming sessions to the explicit intervention group, but without explicit teaching of the target structure using the Shape Coding scheme.

    Behavioral: Implicit intervention (syntactic priming only)

Interventions

  • BehavioralExplicit intervention (Shape Coding+syntactic priming)

    For explicit intervention, a syntactic priming task will be preceded by explicit teaching of the target structure using the Shape Coding scheme adapted to be age- and language (Cantonese)-appropriate. A different set of 10 sentences will be used for teaching in each explicit intervention session, with five sentences used as exemplars for the experimenter to explain the target structure, and the remaining five sentences for children to practice. The syntactic priming session will be presented as a game to sustain the children's interest and to disguise the purpose of the study. Each intervention session will contain 40 pairs of prime-target pictures, 40 pairs of control-target pictures, and 20 pairs of filler pictures, randomly presented to the experimenter and child and controlled by the experimenter. In total, there are 500 doses of SRC-O sentences (50 sentences x10 sessions).

  • BehavioralImplicit intervention (syntactic priming only)

    For implicit intervention, the same 10 sessions of syntactic priming will be provided to the children without explicit instruction of the SRC-O structure using the Shape Coding System. Nonetheless, to make the exposure and dosage as comparable as possible between the two groups, children in the implicit intervention group will also receive 10 listening sessions before the syntactic priming sessions. During the listening sessions, the same sets of sentences used in the explicit instruction sessions will be presented and the children will be instructed to listen closely as the tutor reads aloud the SRC-O sentence. Each listening session will be followed by a syntactic priming session that is identical to that of the explicit intervention group. In total, there are also 500 doses of SRC-O sentences (50 sentences x10 sessions).

06

What researchers measure

Primary outcomes

  1. Production accuracy

    Production accuracy of the target structure

    Time frame: From pretest to the retention test (1 month after all 10 intervention sessions are completed)

  2. Number of successful learners

    The number of successful learners (≥80% accuracy)

    Time frame: From pretest to the retention test (1 month after all 10 intervention sessions are completed)

07

Study locations

1 of 1 sites recruiting
  • Speech and Language Sciences Laboratory (SLS Lab)
    Hong Kong, Hong Kong
    Recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Feb 2024 (actual). Primary completion is estimated for May 2026, 27 months after the start.

Of 72 non-industry interventional studies with no phase under Language Development Disorders, half reached primary completion within 30 months of starting (the median), counting those still running; a quarter within 19 and three quarters within 57. This study's planned 27 months is close to that.

Counting every sponsor, half of 72 studies reached it within 30 months; a quarter within 19 and three quarters within 57.

How these figures are worked out, and which studies are left out of them.

Registered
Apr 24, 2025
First posted
May 1, 2025
StartActual
Feb 10, 2024
Primary completionEst.
May 2026
CompletionEst.
May 2026
Last update
May 4, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on May 4, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06954194
Responsible party
ZHANG Caicai (Associate Professor, The Hong Kong Polytechnic University) — Principal investigator
First posted
May 1, 2025
Start date
Feb 10, 2024
Primary completion
May 2026 (estimated)
Completion
May 2026 (estimated)
Last update
May 4, 2025

Study contacts

Tracy Tang
Contact
tracy-wh.tang@polyu.edu.hk
852 34008541
Caicai Zhang, PhD
principal investigator · The Hong Kong Polytechnic University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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