CClinicalTrials.gg
Not yet recruitingNCT06954168Updated May 13, 2025

The Effects of Smoking on Sleep Quality, Fatigue and Perceived Stress

An observational study in University Students, sponsored by Barış SEVEN. Not yet recruiting. Per ClinicalTrials.gov, last updated 2025-05-13.

Sponsored by Barış SEVEN · Observational

From the registry’s dates

  • Primary completion was expected by Aug 2025, 1 year 1 month ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
528
Sex
All
01

Study summary

Tobacco use is a major cause of death resulting from cancer, cardiovascular diseases, and pulmonary disorders. It is also a risk factor for respiratory and other infections, osteoporosis, diabetes, reproductive disorders, adverse surgical outcomes and delayed wound healing, as well as duodenal and gastric ulcers [1]. Studies project that the number of deaths due to smoking will rise to 8.4 million by 2030 [2]. According to the Tobacco Atlas, in Turkey, 83,100 people die each year due to smoking-related causes.

The negative effects of smoking are not limited to chronic diseases; it can also affect the quality of daily life. In a study involving 3,516 participants, it was reported that both male and female smokers experienced significantly greater difficulty falling asleep compared to non-smokers. They also suffered from non-restorative sleep, frequent awakenings during the night, and difficulty falling back asleep [3]. Furthermore, literature has demonstrated a significant relationship between smoking and perceived stress [4]. Perceived stress is defined as "the feelings or thoughts an individual has about how much stress they are under during a particular period" [5]. Although smoking may temporarily alleviate perceived stress, studies suggest it may actually lead to negative emotional states or exacerbate stress in the long run [6, 7]. In addition, it has been found that smokers tend to feel more tired and become fatigued more quickly compared to non-smokers [8, 9].

The majority of smokers begin smoking during adolescence [10]. In their study, Burt et al. reported that 71% of smokers started smoking at or before the age of 18 [11]. The university period is a critical phase in young individuals' lives, and habits formed during this time can have long-term health consequences. Smoking can affect not only health but also academic performance [12]. Factors such as stress [13], sleep quality [14], and fatigue [15], which have previously been studied in smokers, have also been shown to negatively impact academic achievement. Although academic success will not be directly evaluated in our study, considering the target population, the potential secondary effect of smoking on academic performance further underscores the significance of our research.

This study is designed to compare university students who smoke and those who do not in terms of sleep quality, fatigue, and perceived stress levels. Although there are existing studies that examine these parameters individually or in different populations, to our knowledge, no study has simultaneously assessed all of these factors in a university student sample. Most studies in this field focus on the general population; however, university students represent a specific group due to their stressful academic lives, social pressures, and lifestyle changes. The originality of our study lies in its focus on university students and its comprehensive approach to examining multiple variables concurrently. In this context, the planned research will provide more specific and detailed insights into the factors associated with nicotine dependence and their interrelationships.

02

Conditions studied

  • University Students

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03

In context

Fatigue

1,860 studies on the registry are indexed under Fatigue; 376 are open to participants now.

This study's planned enrollment of 528 is above the median of 100 across 367 observational studies indexed under Fatigue.

Browse Fatigue studies →

Lead sponsor

Barış SEVEN is the lead sponsor of 2 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Sampling method
Probability sample

Study population

University Students

Inclusion criteria

  • be an actively enrolled undergraduate student

Exclusion criteria

Exclusion Criteria:

  • Have a diagnosed sleep disorder such as sleep apnea, insomnia or narcolepsy.
  • Have mental health problems such as diagnosed depression, anxiety disorders or bipolar disorder.
  • Chronic diseases such as diabetes, hypertension, asthma.
  • Conditions that may independently affect sleep, fatigue or stress, such as night shift work and pregnancy.
05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
528 participants (estimated)
Patient registry
No

Groups and cohorts

  • University students who smoke
  • non-smoking university students
06

What researchers measure

Primary outcomes

  1. The Fagerstrom Test for Nicotine Dependence

    Time frame: only once

  2. The Pittsburgh Sleep Quality Index Scoring

    Time frame: only once

  3. The Fatigue Assessment Scale

    Time frame: only once

  4. The Perceived Stress Scale

    Time frame: only once

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 13, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06954168
Lead sponsor
Barış SEVEN
Collaborators
The Scientific and Technological Research Council of Turkey
Responsible party
Barış SEVEN (Ph.D, Gazi University) — Sponsor-investigator
First posted
May 1, 2025
Start date
May 25, 2025 (estimated)
Primary completion
Aug 30, 2025 (estimated)
Completion
Oct 27, 2025 (estimated)
Last update
May 13, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2024. You cannot join it, but the record below documents what was studied.

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Discussion

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