CClinicalTrials.gg
Not yet recruitingNCT06949787Updated Apr 29, 2025

To Compare Sweeping of Membranes Versus Expectant Management for Spontaneous Onset of Labor and Vaginal Delivery.

An interventional study of Membrane sweeping in Post-Term Pregnancy, sponsored by Muhammad Aamir Latif. Not yet recruiting at 1 site in Pakistan. Open to female participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2025-04-29.

Sponsored by Muhammad Aamir Latif · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Oct 2025, 11 months ago, but the record still lists the study as not yet recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
132
Allocation
Randomized
Ages
18 Years to 40 Years
Sex
Female
01

Study summary

The study is planned to fill the gaps regarding the effectiveness of sweeping of membranes versus expectant management in terms of spontaneous onset of labor and vaginal delivery in post-date primigravida.

Read the detailed description

This study is important as it provides localized data on the effectiveness and practicality of membrane sweeping in a low-resource setting, which is underrepresented in current literature. Potential benefits of this research may include reduced need for formal labor induction, lower healthcare costs, and improved maternal and neonatal outcomes. The findings may enhance clinical practices by offering an evidence-based, patient-friendly approach to managing postdate pregnancies, particularly in resource-limited settings where induction facilities are constrained.

02

Conditions studied

  • Post-Term Pregnancy

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03

In context

Pregnancy, Prolonged

30 studies on the registry are indexed under Pregnancy, Prolonged; 2 are open to participants now.

This study's planned enrollment of 132 is close to the median of 132 across 23 interventional studies indexed under Pregnancy, Prolonged.

Browse Pregnancy, Prolonged studies →

Lead sponsor

Muhammad Aamir Latif is the lead sponsor of 56 studies on the registry; 9 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • Primigravid women
  • Aged between 18 and 40 years
  • Gestational age ≥40 weeks, confirmed by ultrasound or early dating scan
  • Singleton pregnancies
  • Cephalic presentation

Exclusion criteria

Exclusion Criteria:

  • Multiple gestations
  • Fetal distress or anomalies detected on ultrasound
  • Contraindications to vaginal delivery (e.g., placenta previa, previous uterine surgery)
  • Previous uterine scar
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
132 participants (estimated)

Study arms

  • Experimental
    Membrane sweeping group

    Participants in the membranes sweeping group will receive membrane sweeping. If labor will not initiate within 48 hours, the procedure will be repeated up to a maximum of three times at 48-hour intervals.

    Procedure: Membrane sweeping

  • No intervention
    Expectant management group

    Women in the expectant management group will receive no mechanical intervention, and these women will be monitored according to the standard protocol until spontaneous labor onset or labor induction will be deemed necessary.

Interventions

  • ProcedureMembrane sweeping

    Participants in the membranes sweeping group will receive membrane sweeping. If labor will not initiate within 48 hours, the procedure will be repeated up to a maximum of three times at 48-hour intervals.

06

What researchers measure

Primary outcomes

  1. Spontaneous onset of labor and vaginal delivery

    The occurrence of regular uterine contractions (contractions occurring every 3-5 minutes, each lasting 30-60 seconds, and progressively increasing in intensity) leading to cervical changes without any form of labor induction will mark the achievement of spontaneous onset of labor.

    Time frame: 6 days

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Study locations

1 site
08

References and documents

Individual participant data

Plan to share: No — If a reasonable request is made, the data can be shared.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 29, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06949787
Lead sponsor
Muhammad Aamir Latif
Responsible party
Muhammad Aamir Latif (Research Consultant, RESnTEC, Institute of Research) — Sponsor-investigator
First posted
Apr 29, 2025
Start date
May 1, 2025 (estimated)
Primary completion
Oct 31, 2025 (estimated)
Completion
Oct 31, 2025 (estimated)
Last update
Apr 29, 2025

Study contacts

Aisha Ashraf
Contact
draisha2020@outlook.com
+923059501195
Tahir Riaz, FCPS
Contact
riaztahira3@gmail.com
+923237426210
Aisha Ashraf
principal investigator · Combined military hospital, Attock, Pakistan
Tahir Ashraf, FCPS
study director · Combined military hospital, Attock, Pakistan

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.

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