An observational study in Pediatrics, Lobar Pneumonia and Inflammatory Markers, sponsored by Children's Hospital of Hebei Province. Completed at 1 site in China. Open to participants aged 1 Year to 12 Years. Per ClinicalTrials.gov, last updated 2025-04-27.
Sponsored by Children's Hospital of Hebei Province · Observational
Integrated nursing and medical management significantly improves clinical symptoms and pulmonary function in children with lobar pneumonia, shortens hospitalization duration, reduces complication rates, and enhances caregiver satisfaction. These findings support its broad clinical applicability and value.
This study aims to evaluate the clinical efficacy of integrated nursing and medical management in the treatment of pediatric lobar pneumonia. Specifically, it assesses its impact on symptom relief, pulmonary function recovery, inflammatory response control, duration of hospitalization, and caregiver satisfaction. Fifty pediatric patients diagnosed with lobar pneumonia and admitted to our hospital between January and December 2023 were selected and randomly assigned to either the observation group or the control group (n = 25 each) using a random number table. The control group received routine nursing care, while the observation group was additionally managed with an integrated nursing and medical approach. The two groups were compared in terms of duration of fever, cough, pulmonary rales, antibiotic treatment, length of hospital stay, pulmonary function parameters (FEV₁, FVC, FEV₁/FVC), inflammatory markers (CRP, WBC, PCT, LDH), overall treatment efficacy, caregiver satisfaction, and incidence of adverse events.
2,044 studies on the registry are indexed under Pneumonia; 283 are open to participants now.
This study's enrollment of 50 is below the median of 203 across 688 observational studies indexed under Pneumonia.
Browse Pneumonia studies →Children's Hospital of Hebei Province is the lead sponsor of 3 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Fifty pediatric patients diagnosed with lobar pneumonia and admitted to our hospital between January and December 2023 were selected and randomly assigned to either the observation group or the control group (n = 25 each) using a random number table.
Exclusion Criteria:
The control group received routine nursing care
Other: control group
the observation group was additionally managed with an integrated nursing and medical approach.
Other: observation group
the observation group was additionally managed with an integrated nursing and medical approach.
The control group received routine nursing care
Time to Clinical Resolution of Symptoms
Duration (in days) from hospital admission until resolution of three key symptoms: fever (axillary temperature \<37.3°C for 24h), cough (absence of cough for 48h), and pulmonary rales (absence on auscultation). Assessed daily by blinded clinicians.
Time frame: From admission until discharge (up to 14 days).
Change in Pulmonary Function (FEV₁, FVC, FEV₁/FVC)
Absolute change in spirometry-measured FEV₁ (L), FVC (L), and FEV₁/FVC ratio (%) from admission to discharge. Assessed using standardized spirometry protocols.
Time frame: Baseline (T0) and discharge (T1; up to 14 days).
Reduction in Inflammatory Markers (CRP, PCT, WBC, LDH)
Percent reduction in serum CRP (mg/L), PCT (ng/mL), WBC (×10⁹/L), and LDH (U/L) levels from admission to discharge.
Time frame: Baseline (T0) and discharge (T1; up to 14 days).
Length of Hospital Stay
Total days from admission to discharge, documented from electronic health records.
Time frame: Up to 14 days.
Parental Satisfaction Rate
Proportion of caregivers reporting "very satisfied" or "satisfied" on a 4-point Likert scale (very satisfied/satisfied/neutral/dissatisfied) at discharge.
Time frame: At discharge (T1; up to 14 days).
Incidence of Complications
Proportion of patients experiencing adverse events (e.g., hemoptysis, pneumothorax, bronchospasm) during hospitalization, verified by imaging/lab reports.
Time frame: From admission to discharge (up to 14 days).
Antibiotic Usage Duration
Total days of intravenous/oral antibiotic therapy, recorded from medication logs.
Time frame: From admission to discontinuation (up to 14 days).
Adherence to Rehabilitation Protocols
Compliance with respiratory exercises (e.g., % of scheduled postural drainage sessions completed), tracked via nursing logs.
Time frame: Daily during hospitalization (up to 14 days).
This study is completed, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.
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Children's Hospital of Hebei Province