An interventional study of cold snare polypectomy and hot snare polypectomy in Colorectal Polyps, sponsored by Shandong University. Not yet recruiting at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2025-04-29.
Sponsored by Shandong University · Not applicable, Interventional, and Treatment
This was a non-inferiority randomized controlled trial designed to compare the efficacy and safety of cold versus hot snare polypectomy for the removal of 4-10 mm pedunculated colorectal polyps. The primary outcome was delayed postpolypectomy bleeding. The secondary outcomes included immediate postpolypectomy bleeding, procedure time, en bloc resection, complete histologic resection, use of haemostatic clips and perforation rate.
312 studies on the registry are indexed under Polyps; 60 are open to participants now.
This study's planned enrollment of 196 is above the median of 150 across 204 interventional studies indexed under Polyps.
Browse Polyps studies →Shandong University is the lead sponsor of 292 studies on the registry; 60 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Procedure: cold snare polypectomy
Procedure: hot snare polypectomy
Cold snare polypectomy was conducted for the removal of 4-10 mm pedunculated colorectal polyps.
Hot snare polypectomy was conducted for the removal of 4-10 mm pedunculated colorectal polyps.
delayed postoperative bleeding
bleeding that developed within 2 weeks after the patient left the endoscopy unit
Time frame: interviewed by telephone on days 2 and 14 after polypectomy
immediate postpolypectomy bleeding
Blood spray or persistent oozing for more than 60 seconds requiring endoscopic intervention
Time frame: during the polypectomy
procedure time
The duration from the appearance of the snare on the monitor to the time when the endoscope was withdrawn from the lesion
Time frame: during the polypectomy
en bloc resection
Removal of a polyp with a single cut and was assessed by the colonoscopist
Time frame: during the polypectomy
complete histologic resection
Clear resection margins, no polyp involvement
Time frame: during the polypectomy
use of haemostatic clips
Time frame: during the polypectomy
perforation rate
Proportion of patients with intraoperative or postoperative perforation
Time frame: during the polypectomy, and interviewed by telephone on days 2 and 14 after polypectomy
Plan to share: No
Start is estimated for May 2025; primary completion for Jan 2027, 19 months later.
Of 68 non-industry interventional studies with no phase under Polyps, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 42. This study's planned 19 months is below that.
Counting every sponsor, half of 79 studies reached it within 23 months; a quarter within 12 and three quarters within 42.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.
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