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CompletedNCT06915051Updated Nov 18, 2025

The Relationship Between Umbilical Cord Coiling Index and Fetal Cardiac Functions.

An observational study in Umbilical Cord Coiling Index and Fetal Cardiac Functions, sponsored by Sanliurfa Education and Research Hospital. Completed at 1 site in Turkey (Türkiye). Open to female participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2025-11-18.

Sponsored by Sanliurfa Education and Research Hospital · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
202
Ages
18 Years to 50 Years
Sex
Female
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Study summary

The maximum efficiency of umbilical cord blood flow depends on a specific number of coils. With modern ultrasound techniques, investigators can now detect cord abnormalities even before birth. In recent years, there has been a renewed interest in the umbilical cord, and several articles have been published regarding the number of coils.In this study, the relationship between the umbilical cord coiling index and fetal cardiac functions was evaluated.

02

Conditions studied

  • Umbilical Cord Coiling Index and Fetal Cardiac Functions

Keywords

  • Umbilical cord coiling index
  • fetal cardiac functions
  • umbilical cord
  • fetal circulation
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In context

Persistent Fetal Circulation Syndrome

38 studies on the registry are indexed under Persistent Fetal Circulation Syndrome; 6 are open to participants now.

This study's enrollment of 202 is above the median of 125 across 12 observational studies indexed under Persistent Fetal Circulation Syndrome.

Browse Persistent Fetal Circulation Syndrome studies →

Lead sponsor

Sanliurfa Education and Research Hospital is the lead sponsor of 23 studies on the registry; 13 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Singleton uncomplicated pregnancies between 20-24 weeks seeking routine antenatal care will be included.

Inclusion criteria

-Singleton uncomplicated pregnancies between 20-24 weeks seeking routine antenatal care.

Exclusion criteria

Exclusion Criteria:

  • Multiple pregnancy
  • Preterm rupture of membranes
  • Chorioamnionitis
  • Placental abruption
  • Severe fetal growth restriction
  • Congenital anomalies of the fetus
  • Preeclampsia
  • Oligohydramnios
  • Maternal diabetes.
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Study design

Observational model
Other
Time perspective
Prospective
Enrollment
202 participants (actual)
Target follow-up
4 Months
Patient registry
Yes

Groups and cohorts

  • This is a single-center study conducted on 200 randomly selected pregnant women with uncomplicated.

    Diagnostic Test: Determining the relationship between the coiling number and fetal echocardiography findings.

Interventions

  • Diagnostic testDetermining the relationship between the coiling number and fetal echocardiography findings.

    Fetal echocardiography findings to be performed simultaneously with the determination of the coiling number.

06

What researchers measure

Primary outcomes

  1. The correlation between the fetal umbilical cord coiling number and the concurrently performed fetal echocardiography findings.

    This study will be a single-center study conducted on two hundred randomly selected pregnant women with uncomplicated singleton pregnancies in the late second trimester (20-24 weeks) who visit our hospital's perinatology outpatient clinic for routine prenatal check-ups. The umbilical cord coiling number and fetal cardiac function measurements will be performed within one hour by the same maternal-fetal medicine specialist.To optimize the quality of Doppler waveforms when assessing vascular structures, measurements will be obtained in the absence of uterine contractions and fetal activity, with an insonation angle as close to zero as possible and less than 30.Three parameters will be used to assess cardiac function: 1. Diastolic function 2. Systolic function 3. Both systolic and diastolic function

    Time frame: The correlation between the fetal umbilical cord coiling index and the echocardiographic findings of the fetus within the first hour will be investigated.

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Study locations

1 site
  • Sanliurfa Education and Research Hospital
    Sanliurfa, Turkey (Türkiye)
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 18, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06915051
Lead sponsor
Sanliurfa Education and Research Hospital
Responsible party
Sponsor
First posted
Apr 8, 2025
Start date
Mar 1, 2025
Primary completion
Jun 15, 2025
Completion
Aug 30, 2025
Last update
Nov 18, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.

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