RecruitingNCT06905600TPHAUpdated Apr 1, 2025

Transient Pseudohypoaldosteronism Affecting Children With Urinary Tract Malformation

An observational study in Pseudohypoaldosteronism, sponsored by University Hospital, Strasbourg, France. Recruiting at 1 site in France. Open to participants aged 1 Year to 6 Years. Per ClinicalTrials.gov, last updated 2025-04-01.

Sponsored by University Hospital, Strasbourg, France · Observational

From the registry’s dates

Primary completion was expected by Dec 2025, 10 months ago, but the record still lists the study as recruiting.
Started Jan 2024; still recruiting 2 years 8 months later.

Study type: Observational
Model: Case-control
Time perspective: Retrospective
Enrollment: 50
Ages: 1 Year to 6 Years
Sex: All

Study summary

Pseudohypoaldosteronism is a pathology affecting children under 6 months of age, little known but which can have serious consequences.

There are no real figures on the prevalence of this pathology in France. The exact pathophysiology is not known and the management is not currently codified.

This is why it is interesting to study this pathology and its treatment on a national scale in order to think about the best possible treatment, as well as to raise awareness of this pathology among different health professionals.

Conditions studied

Pseudohypoaldosteronism

Keywords

Pseudohypoaldosteronism
pseudohypoaldosteronism in children

In context

Lead sponsor

University Hospital, Strasbourg, France is the lead sponsor of 966 studies on the registry; 342 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 1 Year to 6 Years
Sexes eligible: All
Accepts healthy volunteers: No
Sampling method: Non-probability sample

Study population

Minor subjects aged less than 6 years at the time of diagnosis of pseudohypoaldosteronism in the context of urinary malformation and/or urinary infection between January 1, 2018 and December 31, 2023

Inclusion criteria

Minor subjects aged less than 6 years at the time of diagnosis
Diagnosis of pseudohypoaldosteronism in the context of urinary malformation and/or urinary infection between January 1, 2018 and December 31, 2023
Subject (and/or their parental authority) having not expressed, after information, their opposition to the reuse of their data for the purposes of this research.

Exclusion criteria

Exclusion Criteria:

Subject (or their parents) having expressed their (their) opposition to participating in the study

Study design

Observational model: Case-control
Time perspective: Retrospective
Enrollment: 50 participants (estimated)
Patient registry: No

What researchers measure

Primary outcomes

National comparison of clinical and therapeutic practices concerning the management of pseudohypoaldosteronism in children with urinary malformations and/or urinary infections
This study compares clinical and therapeutic practices The retrospective analysis of the data will be carried out using classic statistical tests (Student's test, Fisher's test, ROC curve)
Time frame: Up to 1 year

Study locations

1 of 1 sites recruiting

Service pédiatrie 1 - CHU de Strasbourg - France
Strasbourg, 67091, France
- Ariane ZALOSZYC, MD · Contact · ariane.zaloszyc@chru-strasbourg.fr · 33 3 88 12 77 42
- Ariane ZALOSZYC, MD · Principal investigator
- Inès BERNHARD, MD · Sub investigator
Recruiting

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Apr 1, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT06905600
Lead sponsor: University Hospital, Strasbourg, France
Responsible party: Sponsor
First posted: Apr 1, 2025
Start date: Jan 31, 2024
Primary completion: Dec 2025 (estimated)
Completion: Dec 31, 2025 (estimated)
Last update: Apr 1, 2025

Study contacts

Ariane ZALOSZYC, MD

Contact

ariane.zaloszyc@chru-strasbourg.fr

33 3 88 12 77 42

Oversight

Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No

View the source record on ClinicalTrials.gov ↗

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Discussion

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Other studies in this condition

Pseudohypoaldosteronism

Other studies from this sponsor

University Hospital, Strasbourg, France

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