An interventional study of Blood samples for inflammatory markers and Placental Extract in Gestational Diabetes Mellitus (GDM), sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS. Active, not recruiting at 1 site in Italy. Open to female participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-03-19.
Sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Not applicable, Interventional, and Basic science
The aim of this study is to investigate the placental inflammation in women with gestational diabetes mellitus, in particular the role of inflammasome NLRP3 and the chemokine scavenger decoy receptor D6
The aim of this study is to investigate systemic and placental inflammation in women with gestational diabetes mellitus, in particular the role of inflammasome NLRP3 and the chemokine scavenger decoy receptor D6, compared to women with uncomplicated pregnancy
842 studies on the registry are indexed under Diabetes, Gestational; 198 are open to participants now.
This study's planned enrollment of 40 is below the median of 110 across 550 interventional studies indexed under Diabetes, Gestational.
Browse Diabetes, Gestational studies →Fondazione Policlinico Universitario Agostino Gemelli IRCCS is the lead sponsor of 920 studies on the registry; 529 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Blood and placenta sampling will be obtained from cases= women with gestational diabetes mellitus
Other: Blood samples for inflammatory markers · Other: Placental Extract
Blood and placenta sampling will be obtained from controls= women with uncomplicated pregnancy
Other: Blood samples for inflammatory markers · Other: Placental Extract
Blood sampling
Placental sampling after caesarean section
Placental inflammation
Analysis of protein expression of inflammasome NLRP3 and D6 scavenger receptor in placental tissue.
Time frame: At delivery/birth
This study is active, not recruiting, as verified in Jun 2024. You cannot join it, but the record below documents what was studied.
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS