An interventional study of Testing Peer navigation and PrEP Intervention in Adolescent HIV Infection, sponsored by Northwestern University. Recruiting at 6 sites in Nigeria. Open to participants aged 15 Years to 24 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-08.
Sponsored by Northwestern University · Not applicable, Interventional, and Prevention
Two combination interventions (HIV Case Finding Intervention and HIV Treatment Intervention), each with mHealth and Peer Navigation components, will be evaluated in two 48-week parallel hybrid effectiveness/implementation trials among youth aged 15-24 in Nigeria.
Two combination interventions, each with mHealth and Peer Navigation components, will be evaluated in two 48-week parallel hybrid effectiveness/implementation trials among youth aged 15-24 in Nigeria:
HIV Case Finding Intervention: single arm trial of an HIV case finding and linkage to care intervention targeting young men at risk of HIV infection (n = 6000), particularly young men who have sex with men (YMSM) in Akwa Ibom, Benue, Enugu, Kano, Taraba, and Lagos states who complete HIV testing.
Objectives: To determine the effectiveness of the intervention to:
Objectives: To determine the effectiveness of the intervention on
4,734 studies on the registry are indexed under HIV Infections; 244 are open to participants now.
This study's planned enrollment of 500 is above the median of 80 across 3,489 interventional studies indexed under HIV Infections.
Browse HIV Infections studies →Northwestern University is the lead sponsor of 1,423 studies on the registry; 198 are open to participants now.
Of its 105 completed or terminated interventional studies of FDA-regulated products, 78 (74%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Case Finding Intervention:
HIV Treatment Intervention:
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
HIV
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Combination HIV case finding and linkage to care intervention
Behavioral: Testing Peer navigation · Behavioral: PrEP Intervention · Behavioral: Social Media Outreach
Combination HIV treatment intervention vs. standard of care adherence among youth newly diagnosed with HIV and initiating ART
Behavioral: Treatment Peer Navigation · Behavioral: SMS Test messaging · Other: Adherence standard of care
Peer navigators will promote HIV testing in YMSM and linkage to care if HIV-positive
Motivational-interviewing to promote uptake of PrEP among those who test HIV-negative
Peer navigators will provide assistance and support to youth with HIV to optimize adherence to ART
Social media outreach to identify youth at risk for HIV
Text (SMS) messages to remind and encourage youth to adhere to their ART
Standard of care HIV treatment adherence
Case Finding: HIV-positive serostatus
HIV-positive serostatus based on rapid test with confirmation
Time frame: 48 weeks
Treatment: Viral suppression
Viral suppression (\< 200 copies per mL)
Time frame: 48 Weeks
Case Finding: Linkage to HIV care
Linkage to HIV care within 30 days of positive HIV test
Time frame: 48 Weeks
Case Finding: PrEP among youth who test HIV-negative
PrEP uptake among youth who test HIV-negative
Time frame: 48 weeks
Treatment: Adherence to antiretroviral therapy (ART)
\> 90% adherence to ART
Time frame: 48 Weeks
Started Feb 2025 (actual). Primary completion is estimated for Aug 2028, 42 months after the start.
Of 393 non-industry interventional studies with no phase under HIV Infections, half reached primary completion within 28 months of starting (the median), counting those still running; a quarter within 16 and three quarters within 45. This study's planned 42 months is above that.
Counting every sponsor, half of 402 studies reached it within 28 months; a quarter within 16 and three quarters within 45.
How these figures are worked out, and which studies are left out of them.
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