An interventional study of high intensity functional training in Parkinson Disease, sponsored by Fundacion Para La Investigacion Hospital La Fe. Recruiting at 1 site in Spain. Open to participants aged 40 Years to 80 Years. Per ClinicalTrials.gov, last updated 2025-03-17.
Sponsored by Fundacion Para La Investigacion Hospital La Fe · Not applicable, Interventional, and Treatment
Parkinson's disease (PD) is a progressive and chronic neurodegenerative disease, which presents signs and symptoms both motor (impaired gait, posture, balance, etc.) and cognitive (memory loss, dementia, etc.), all of which are causing disability and assuming a high economic cost. Currently, there are already certain authors who have shown how a high-intensity interval training (HIIT) protocol produces improvements in cognitive and physical performance in healthy adults6 and in people with multiple sclerosis. However, another modality has been created, such as high-intensity functional training (HIFT), which can benefit different populations, both healthy and pathological, due to the multimodal nature of the exercises. Thanks to multimodality, more aspects such as agility, coordination and precision of movements are worked on compared to unimodal HIIT programs that make this relevant work difficult in a person's daily life. The current study aims to demonstrate the effectiveness of a HIFT training protocol in a specific population, such as people with Parkinson's disease.
The hypothesis is that high-intensity functional training (HIFT), at a motor and cognitive level, provides a greater benefit than conventional programs of strength, balance and cognition, on the functionality and cognitive capacity of people with Parkinson's disease.
Overall objective:
Secondary objectives:
4,487 studies on the registry are indexed under Parkinson Disease; 1,082 are open to participants now.
This study's planned enrollment of 34 is below the median of 40 across 3,294 interventional studies indexed under Parkinson Disease.
Browse Parkinson Disease studies →Fundacion Para La Investigacion Hospital La Fe is the lead sponsor of 7 studies on the registry; 1 is open to participants now.
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Exclusion Criteria:
The experimental group will perform a high-intensity functional training program twice a week for 10 weeks.
Other: high intensity functional training
The control group will continue to carry out their physical and cognitive exercise routine during the week, recording their activity in days and sessions.
The pillar of rehabilitation will be based on high intensity functional training. 45-minute sessions divided into 5 minutes of warm-up, 35 minutes of functional exercises, and 5 minutes of going back to bed and cooling down. The 35 minutes of exercises were divided into 3 categories: lower extremity exercises, upper extremity exercises, and static and dynamic coordination and balance exercises. Each category will consist of 3 exercises per session, performing 2-3 series with a maximum of repetitions of 10-RM. The progression of the load will be progressively increased in weeks 3, 5 and 8 between 40-60% of the 1-RM.
Also known as: HIFT
Short physical performance battery (SSPB)
Functional performance evaluation.
Time frame: 10 minutes
Trail Making Test A y B
Evaluation of visual search, scanning, processing speed, mental flexibility and executive functions.
Time frame: 15 minutes
SF-12 Health Questionnaire
Assessing Perceived Quality of Life
Time frame: 10 minutes
Barthel index
Evaluation of the degree of dependence in activities of daily living.
Time frame: 10 minutes
fall risk assessment scale
Fall Risk Assessment
Time frame: 5 minutes
2-minute walk test (2-MWT)
Evaluation of functional capacity
Time frame: 5 minutes
Mini Mental State Examination
Assessment of cognitive function
Time frame: 20 minutes
The Borg Scale
Rating of perceived exertion
Time frame: 2 minutes
Plan to share: No
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Fundacion Para La Investigacion Hospital La Fe