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CompletedNCT06870864Updated Mar 11, 2025

Conservative Versus Operative Management in Adhesive Intestinal Obstruction

An observational study in Adhesive Intestinal Obstruction, sponsored by Sohag University. Completed at 1 site in Egypt. Open to participants aged 6 Years to 70 Years. Per ClinicalTrials.gov, last updated 2025-03-11.

Sponsored by Sohag University · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
50
Ages
6 Years to 70 Years
Sex
All
01

Study summary

This study aims to evaluate the role of Conservative management in patients with adhesive Intestinal Obstruction Regarding the selection criteria of the patients, duration of conservative route, success rate, and recurrence of adhesions and avoiding the surgical route complications.

Read the detailed description

Adhesive Intestinal Obstruction is very common and represents a serious life threatening condition, which can be caused by congenital band, following abdominal surgeries and other medical conditions like tuberculosis.

The management options for adhesive intestinal obstruction (AIO) could be operative treatment (open-laparoscopy) or non-operative (conservative management) according to many reasons.

Some reports indicate that the operative management for adhesive Intestinal obstruction lead to further adhesions in the future in addition to other possible complications (anaesthetic - iatrogenic injury during adhesolysis - wound site infections - illius-long hospital stay).

The Conservative route is recommended in all patients except those with signs of peritonitis, strangulation, or bowel ischemia which would have been diagnosed during physical examination and imaging.

A few studies compared the advantages, safety, and less complications of Conservative versus operative management. Therefore, this study will be conducted on patients with adhesive Intestinal Obstruction to compare the effectiveness of Conservative versus operative management regarding the selection criteria for the patients, the duration of the Conservative route, things to be done and what need to be observed during the conversation time.

02

Conditions studied

  • Adhesive Intestinal Obstruction
03

In context

Intestinal Obstruction

104 studies on the registry are indexed under Intestinal Obstruction; 15 are open to participants now.

This study's enrollment of 50 is below the median of 107 across 40 observational studies indexed under Intestinal Obstruction.

Browse Intestinal Obstruction studies →

Lead sponsor

Sohag University is the lead sponsor of 1,230 studies on the registry; 636 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
6 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

patients with adhesive Intestinal Obstruction at Department of General Surgery, Oncological and Laparoscopic Surgeries, Sohag University Hospitals, Sohag, Egypt

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age 6-70 years.
  • Both sexes.
  • Complete \ Partial adhesive Intestinal Obstruction, with CT Abdomen and pelvis with oral and IV Contrast.

Exclusion criteria

Exclusion Criteria:

  • Patients with signs of Strangulation
  • Patients with signs of peritonitis.
  • Patients with signs of bowel ischemia
  • Failure of Conservative management for more than 72 hours.
  • Vitally unstable patients
  • Patients with comorbidities which need rapid interventions.
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
50 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. X-Ray Changes

    Daily Chest Abdomen X-ray Erect copies to evaluate the improvement of the Intestinal Obstruction through evaluation of the X-ray findings (Air fluid levels).

    Time frame: 72 Hours

  2. Passability Status

    Daily history taking records and per rectal examination findings to evaluate the passability status (stool /flatus)

    Time frame: 72 Hours

  3. Hospital Stay Duration

    The Conservative management in patients with adhesive Intestinal Obstruction will avoid them the surgical route which requires long hospital stay postoperative

    Time frame: from 3 to 5 days.

  4. Vomiting

    Frequency and severity of vomiting will be collected to help in prognosis prediction

    Time frame: 72 Hours

  5. Abdominal Signs

    Data collected about Daily abdominal examination findings (Distention, Intestinal sounds, abdominal pain and Per rectal examination).

    Time frame: 72 Hours

Secondary outcomes

  1. Recurrence of Attacks

    past history about the previous attacks of the adhesive Intestinal Obstruction

    Time frame: two years previous the onset of the current attack. (During the last two years before the admission)

  2. Past Surgical History

    Detailed history about the previous operations to determine the relationship between different operations and adhesive Intestinal Obstruction

    Time frame: two years previous the onset of the current attack. (During the last two years before the admission)

07

Study locations

1 site
  • Faculty of Medicine, Sohag University
    Sohag, Egypt
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 11, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06870864
Lead sponsor
Sohag University
Responsible party
Osama Khaled Ahmed (Principal investigator, Sohag University) — Principal investigator
First posted
Mar 11, 2025
Start date
Apr 1, 2024
Primary completion
Sep 1, 2024
Completion
Jan 1, 2025
Last update
Mar 11, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.

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