An observational study in Thrombocytopenia, sponsored by Kepler University Hospital. Active, not recruiting at 1 site in Austria. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2025-03-11.
Sponsored by Kepler University Hospital · Observational
Viscoelastic testing is a highly recommended cornerstone of modern coagulation medicine, reducing transfusion needs. A disadvantage of viscoelastic tests is the impossibility of making a definitive statement about the platelet count.
Therefore, the aim of this retrospective observational study is, on the one hand, to predict the platelet count based on standard ROTEM parameters with the help of several machine learning methods and, on the other hand, to detect a low platelet count ( \<100000 ml-1 and \< 50000 ml-1).
697 studies on the registry are indexed under Thrombocytopenia; 153 are open to participants now.
This study's planned enrollment of 2,500 is above the median of 120 across 183 observational studies indexed under Thrombocytopenia.
Browse Thrombocytopenia studies →Kepler University Hospital is the lead sponsor of 32 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
surgical patients in the operating room and the intensive care of participating centers
Exclusion Criteria:
Predicition of platelet conentration from ROTEM measurements using machine learning
Several machine learning techniques for the prediction of the platelet concentration from ROTEM parameters (regression approach), namely linear regression, Random Forest, neural network, gradient boosting machine (GBM) and adaptive boosting (ADA) will be assessed. Describing the quality of these prediction models, the mean square error (MSE), the root of the mean of the square of errors(RMSE), the mean absolute error (MAE), and the root mean squared logarithmic error (RMSLE), and the coefficient of determination (R2) will be used.
Time frame: Obtained ROTEM analyses are the baseline at all four centres and patients will be included if platelets were determined concomitantly within three hours on the same day.
This study is active, not recruiting, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
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Kepler University Hospital