An interventional study of Eccentric bike and conventional group in COPD (Chronic Obstructive Pulmonary Disease), sponsored by Fu Jen Catholic University. Withdrawn at 1 site in Taiwan. Per ClinicalTrials.gov, last updated 2026-02-04.
Sponsored by Fu Jen Catholic University · Not applicable, Interventional, and Other
This study aims to investigate the effects of elliptical exercise on the six-minute walk test and quality of life in patients with chronic obstructive pulmonary disease (COPD) to identify the most efficient exercise training method.
Background: Chronic respiratory diseases, including COPD, are leading causes of chronic illness and mortality worldwide. However, limitations in ventilation and muscle function restrict COPD patients from engaging in higher-power exercise therapies. Compared to concentric exercise, eccentric exercise can effectively improve health-related fitness and quality of life at lower cardiopulmonary and metabolic loads. Pulmonary rehabilitation programs have been shown to effectively improve symptoms of chronic respiratory diseases, increase exercise capacity, enhance quality of life, delay disease progression, prevent and treat acute exacerbations, and reduce mortality. Therefore, it is hoped that a "safe and effective" eccentric exercise strategy can be designed for COPD patients to comprehensively improve their cardiopulmonary/muscle fitness and quality of life, thereby improving the course of their disease.
Study Design: This is a one-year, single-center, prospective randomized controlled trial. Methods: This study plans to enroll 60 participants who will be randomly assigned to control and experimental groups. The intervention will take place in the pulmonary rehabilitation room on the sixth floor of Fu Jen Hospital. Each group will undergo a functional fitness test and complete a quality of life questionnaire before and after 24 sessions (over 12 weeks) of exercise training.
Effect: It is anticipated that after 24 sessions of elliptical exercise training, there will be an improvement in the functional fitness and in quality of life related to physical activity function.
Key words: Pulmonary rehabilitation; eccentric exercise; chronic obstructive pulmonary disease; cardiopulmonary fitness; functional fitness
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Exclusion Criteria:
Received eccentric cycling exercise
Device: Eccentric bike
Undergoing conventional treatment
Other: conventional group
Received eccentric cycling exercise
Received conventional treatment
six minute walk test
functional performance
Time frame: 12 weeks
time up and go
functional performance
Time frame: 12 weeks
stairs ascending and descending walking time
functional performance
Time frame: 12 weeks
Plan to share: No
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This study is withdrawn, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
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Pulmonary Disease, Chronic Obstructive→
Fu Jen Catholic University