An interventional study of Intraoperative area irrigation in Colorectal Cancer, Surgical Site Infection and Chlorhexidine, sponsored by Nanchong Central Hospital. Recruiting at 1 site in China. Open to participants aged 18 Years to 85 Years. Per ClinicalTrials.gov, last updated 2026-03-31.
Sponsored by Nanchong Central Hospital · Not applicable, Interventional, and Prevention
The aim of this study was to compare the effectiveness of chlorhexidine versus saline in flushing the surgical area during colorectal cancer surgery. The primary outcomes included surgical site infection, postoperative complication rates, et al.
5,599 studies on the registry are indexed under Colorectal Neoplasms; 1,459 are open to participants now.
This study's planned enrollment of 532 is above the median of 77 across 4,123 interventional studies indexed under Colorectal Neoplasms.
Browse Colorectal Neoplasms studies →Nanchong Central Hospital is the lead sponsor of 20 studies on the registry; 13 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
After colorectal cancer surgery, flush the surgical area with chlorhexidine solution 1 minute before suturing the skin.
Procedure: Intraoperative area irrigation
Procedure: Intraoperative area irrigation
Procedure: Intraoperative area irrigation
Procedure: Intraoperative area irrigation
After colorectal cancer surgery, flush the surgical area with chlorhexidine solution 1 minute before suturing the skin. According to abdominal cavity contamination, bleeding and tumor invasion to determine the flushing time and flush fluid volume. If the abdominal cavity infection is more serious or exudate more, the flushing time can be relatively prolonged. At last, there were no obvious blood residue, tissue fragments and suppurative secretions in abdominal cavity. Ensure that the surgical field of vision is clear, the surface of each organ is smooth, and there is no abnormal exudate.
Number of participants with Surgical site infection within 30 days
Any surgical site infection within 30 days of surgery is classified as superficial incision, deep mouth, or organ space infection according to the U.S. Centers for Disease Control and Prevention standards.
Time frame: 30 days
Number of participants with Postoperative complication within 30 days
Including anastomotic fistula, anastomotic hemorrhage, intestinal obstruction, deep vein thrombosis and so on
Time frame: 30 days
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Nanchong Central Hospital