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CompletedNCT06866821Updated Mar 12, 2025

Spinal Mobilization and PNF Comparison on Pain, Disability in Patients With Cervical Radiculopathy

An interventional study of SMWAM's and PNF C-R Technique and PNF C-R Technique and PT Protocol in Cervical Radiculopathy, sponsored by Riphah International University. Completed at 1 site in Pakistan. Open to participants aged 21 Years to 50 Years. Per ClinicalTrials.gov, last updated 2025-03-12.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 1 month after the study started (first participant enrolled Jan 2024, registered Mar 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
38
Allocation
Randomized
Ages
21 Years to 50 Years
Sex
All
01

Study summary

As in this modern era of digitalization; mobile phones, touch pads and computers devices use is increasing, neck pain that radiates into upper limb is also becoming common due to such devices long term use in bad postures or positions for more workload. The resulted findings could significantly contribute to the refinement of rehabilitation interventions, offering a more holistic and tailored approach for addressing cervical radiculopathy sensory and motor symptoms, ultimately improving individuals daily living activities and life quality. It will be helpful for physiotherapists to find evidence about comparison of mulligan's spinal mobilization along with arm movement with proprioceptive neuromuscular facilitation technique on pain, disability and range of motion in patients with cervical radiculopathy. It will be beneficial for patients also to improve pain, activities of daily living and working tasks in a comfortable position.

Read the detailed description

Cervical radiculopathy is a clinical situation in which reflex, motor, and sensory alterations e.g. radicular pain, paresthesia, or numbness might be present and might be increased by neck bad postures and movements. Due to sustained forward head and neck posture and repetitive movements, cervical pain and numbness is becoming common in office, bank and online workers. The cervical radiculopathy new cases report yearly is almost 107.3 per 1 lac for men and 63.5 per 1 lac for women. It is essential to find new efficient methods of cervical radiculopathy physical therapy management.

Males and females of age 21-50 years old added in this study. Screening tests will include upper limb tension tests (ULTT), spurling (compression) test and distraction test. Subjects randomly assigned into two groups by lottery method. Experimental group (N=19) received Mulligan's spinal mobilization with arm movements (SMWAMs) and proprioceptive neuromuscular facilitation (PNF) contract-relax technique and control group (N=19) received Proprioceptive neuromuscular facilitation (PNF) contract-relax technique and standard physical therapy protocol including passive stretching exercises (3 sets of 10 repetitions) and isometric strengthening exercises (2 sets of 10 repetitions). Outcome measures included numeric pain rating scale (NPRS) for pain, neck disability index (NDI) for functional disability and goniometer for range of motion (ROM). Data analyzed by statistical package for social sciences (SPSS 26) software.

02

Conditions studied

  • Cervical Radiculopathy

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Keywords

  • Cervical Radiculopathy
  • Pain
  • Range of Motion
  • Distraction
  • Proprioceptive Neuromuscular Facilitation
03

In context

Radiculopathy

488 studies on the registry are indexed under Radiculopathy; 141 are open to participants now.

This study's enrollment of 38 is below the median of 60 across 376 interventional studies indexed under Radiculopathy.

Browse Radiculopathy studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,133 studies on the registry; 633 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
21 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Both males, females of 21 years to 50 years old
  • Patients already diagnosed by orthopedicians
  • Patients with positive screening (upper limb tension, spurling \& distraction) tests

Exclusion criteria

Exclusion Criteria:

  • History of trauma, fracture and previous surgery
  • Any pathological condition, spinal instability and tumor
  • VBI (Vertebral-Basillar Insufficiency) and cervical instability/spondylolisthesis
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
38 participants (actual)

Study arms

  • Experimental
    Experimental Group (SMWAM's and PNF C-R Technique)

    Experimental group received Mulligan's Spinal Mobilization with Arm Movements and Proprioceptive Neuromuscular Facilitation contract-relax technique.

    Other: SMWAM's and PNF C-R Technique

  • Experimental
    Control Group (PNF C-R Technique and PT Protocol)

    Control group received Proprioceptive Neuromuscular Facilitation Contract-relax Technique and Physical Therapy protocol.

    Other: PNF C-R Technique and PT Protocol

Interventions

  • OtherSMWAM's and PNF C-R Technique

    Treatment provided 3 days every week in 6 total weeks with 1 meeting per day, 3 bunches of 10 times repeat and resting period of one minute among bunches. This group received Mulligan's spinal mobilization with arm movement and proprioceptive neuromuscular facilitatin contract-relax technique. Previous to mobilization, all patients got hot pack (10 minutes) and active range of motion warm up exercises (2 sets of 10 repetitions) and did isometric neck exercise as a home plan of care. Mobilisation (22) was done depending on the side of involvement, the corresponding spinous process would be mobilised combined with different movements of shoulder (flexion/ abduction/ horizontal abduction/ horizontal adduction). Proprioceptive neuro-muscular facilitation contract relax technique performed with 3 repetitions in each cervical movement (flexion, extension, lateral flexion and rotation) (27).

  • OtherPNF C-R Technique and PT Protocol

    Treatment provided 3 days every week in 6 weeks with 1 meeting per day, 5 clusters of 3 times repeat and resting period of one minute among clusters. Regime of training involved PNF (proprioceptive neuromuscular facilitation) contract-relax method along with the standard physical therapy protocol which includes passive stretching (3 sets of 10 repetitions) and isometric strengthening exercises (2 sets of 10 repetitions). Proprioceptive neuro-muscular facilitation contract relax technique performed with 3 repetitions in each cervical movement (flexion, extension, lateral flexion and rotation) (27).

06

What researchers measure

Primary outcomes

  1. Pain by Numeric Pain Rating Scale

    This was used for pain intensity assessment. Patient rested on stool or chair and ordered to score resting pain extent in between 0 and 10 range; 0 means without pain and 10 means much high pain as possible in 10cm numbers line.

    Time frame: 6 weeks

  2. Neck level of disability by Neck Disability Index

    Neck disability Index was used for functional disability of neck assessment. NDI is a 10-items questionnaire that assesses the effect of neck signs and symptoms on daily living functional activities. Every item is marked from range 0 to 5, along with total score from 0 to 50 range and maximum scores means maximum disability. NDI has reliability acceptable in the self-perceptual disability assessment and an MCID (minimal clinically important difference) of 8.5 points in cervical radiculopathy patients.

    Time frame: 6 weeks

  3. Cervical Range of Motion by Goniometer

    Goniometer was used for active cervical spine range of the motion (flexion, extension, rotation, side bending) assessment. Side bending, rotation measured on the symptomatic and asymptomatic both sides.

    Time frame: 6 weeks

07

Study locations

1 site
  • Riphah International University
    Lahore, Punjab 54000, Pakistan
08

References and documents

Publications

  • Kamal AS, Zakaria HM, Elsamra MK, Gaballah MA, Elrewainy RM. EFFICACY OF PROPRIOCEPTIVE TRAINING PARADIGM ON CERVICAL RADICULOPATHY. Assessment. 2023;1000(2):12.
  • Gashi AI, Kovačič T, Gashi F, Azemi A. The effect of proprioceptive neuromuscular facilitation technique on treating cervical radiculopathy. Journal of Physical Education and Sport. 2023;23(3):722-9.
  • Taneja D, Saharan A, Ranjeeta W, Sharma M, Saharan M, Dubey S, et al. Effect of Mulligan's Smwam among Subjects with UnilateralCervical Radiculopathy. Eduzone: International Peer Reviewed/Refereed Multidisciplinary Journal. 2023;12(1):11-22.

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 12, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06866821
Lead sponsor
Riphah International University
Responsible party
Sponsor
First posted
Mar 10, 2025
Start date
Jan 12, 2024
Primary completion
Feb 21, 2025
Completion
Feb 21, 2025
Last update
Mar 12, 2025

Study contacts

Muhammad Azeem
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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