An interventional study of Active Comparator and Placebo Comparator in Skin Aging, sponsored by Shanghai Meifute Biotechnology Co., Ltd. Completed at 1 site in China. Open to female participants aged 35 Years to 55 Years. Per ClinicalTrials.gov, last updated 2025-02-28.
Sponsored by Shanghai Meifute Biotechnology Co., Ltd · Not applicable, Interventional, and Treatment
To assess if oral intake of collagen peptide can improve skin conditions such as skin thickness, density and firmness.
This is an one site, randomized, double-blind controlled clinical trial to assess the oral supplement of LISAVEI collagen peptide solid beverage on skin ageing improvement. Study product with collagen peptide and placebo product without collagen were randomly assigned to 90 eligible participants enrolled according to the inclusion and exclusion criteria. They took the assigned product once daily dissolved in 100 ml warm water for 12 weeks with 4-week regression phase(without intake of the test products), and visit the study site in Shanghai for four times(before starting the treatment, after 8 and 12 weeks, and 4 weeks after the last intake). Skin measurements including skin firmness, skin density, skin hydration and skin barrier were carried out at each visit with professional equipment and imaging system. Data were analyzed to validate if the administration of the test collagen peptide solid beverage will improve skin aging parameters such as firmness, thickness, density, hydration and skin barrier compared to placebo. The lasting effect was also observed by comparing between the two groups after 4-week regression time.
538 studies on the registry are indexed under Skin Diseases; 92 are open to participants now.
This study's enrollment of 90 is above the median of 60 across 372 interventional studies indexed under Skin Diseases.
Browse Skin Diseases studies →This is the only study on the registry with Shanghai Meifute Biotechnology Co., Ltd as lead sponsor.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria
collagen peptide solid beverage
Dietary Supplement: Active Comparator
placebo solid beverage
Dietary Supplement: Placebo Comparator
LISAVEI collagen peptide solid beverage ( contain 5 g collagen peptide)，once daily for 12 weeks
placebo solid beverage (Maltodextrin with edible flavor)，once daily for 12 weeks
Also known as: placebo solid beverage
Skin firmness
The changes of skin firmness parameter tested by Cutometer MPA580
Time frame: before product treatment (T 0), after 8 weeks(T 1)and 12 weeks(T 2) of daily product intake, 4 weeks after the last intake(T 3, 4-week regression phase)
Skin thickness
The changes of skin thickness （μm） tested by Ultrascan UC 22
Time frame: before product treatment (T 0), after 8 weeks(T 1)and 12 weeks(T 2) of daily product intake, 4 weeks after the last intake(T 3, 4-week regression phase)
Skin density
The changes of skin density tested by Ultrascan UC 22
Time frame: before product treatment (T 0), after 8 weeks(T 1)and 12 weeks(T 2) of daily product intake, 4 weeks after the last intake(T 3, 4-week regression phase)
Skin hydration
The changes of skin hydration tested by Corneometer CM825
Time frame: before product treatment (T 0), after 8 weeks(T 1)and 12 weeks(T 2) of daily product intake, 4 weeks after the last intake(T 3, 4-week regression phase)
Skin barrier
The changes of Trans Epidermal Water Loss (skin barrier parameter) tested by Tewameter TM300
Time frame: before product treatment (T 0), after 8 weeks(T 1)and 12 weeks(T 2) of daily product intake, 4 weeks after the last intake(T 3, 4-week regression phase)
Facial image
Photo documents of left, right and frontal facial views
Time frame: before product treatment (T 0), after 8 weeks(T 1)and 12 weeks(T 2) of daily product intake, 4 weeks after the last intake(T 3, 4-week regression phase)
This study is completed, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.
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