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CompletedNCT06795802Cardio'ActivUpdated Dec 10, 2025

Effect of Evaluative Conditioning on Intensity of Physical Activity of Patients Doing Cardiac Rehabilitation

An observational study in Cardiovascular Diseases, sponsored by Centre Hospitalier Universitaire de Nīmes. Completed at 1 site in France. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2025-12-10.

Sponsored by Centre Hospitalier Universitaire de Nīmes · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
24
Ages
18 Years to 75 Years
Sex
All
01

Study summary

The hypothesis is that, compared to those in the control group (i.e., diet-related evaluative conditioning), participants in the Physical Activity (PA) group (i.e. PA-friendly evaluative conditioning) will exhibit (1) a higher intensity (power setting) on an ergocycle during a free Physical Activity session in their rehabilitation program and (2) A greater increase in the implicit attitude score.

The primary objective will be to evaluate the effect of evaluative conditioning (EC) on the intensity of physical activity produced by post-myocardial infarction patients involved in a cardiac rehabilitation program.The secondary objective of this study will be to evaluate the mediating effect of implicit attitude change in the effect of evaluative conditioning on adopted behaviors.

Read the detailed description

More specifically, post-myocardial infarction physical activity has been shown to reduce cardiac morbidity and mortality. Indeed, exercise improves cardiovascular health through mechanisms such as lowering blood pressure, weight reduction, and increased insulin sensitivity. Although there are no formal guidelines for physical activity (PA) after Myocardial Infarction, patients are encouraged to achieve 150 minutes of low-to-moderate intensity PA per week.

Nevertheless, despite the growing body of scientific evidence and the widespread dissemination of information about the benefits of PA, the recommendations have been difficult for post-myocardial infarction patients to comply with. There is evidence to suggest that post-cardiac rehabilitation patients struggle to maintain sustained PA. This may be due to a number of barriers, including fatigue, mood disorders, a lack of motivation, or kinesiophobia.

Continued improvements in monitoring physical activity and the development of policies and programs to increase activity levels appears to be a necessity. This may reduce the burden of physical inactivity and noncommunicable diseases (eg, cardiovascular disease). Therefore, one of the major challenges is to succeed in identifying the main determinants playing a role in the lack of adoption of regular PA. Indeed, targeting these determinants would ultimately allow us to improve the PA promotion strategies already in place for the population. However, maintenance of a practice over time is a complex issue that may be influenced by a multitude of factors. Among these, previous work suggests that the identification of motivational determinants of physical activity represents a relevant research object in this context.

02

Conditions studied

  • Cardiovascular Diseases

Keywords

  • Cardiovascular Rehabilitation
  • Motivation
  • Physical Activity
03

In context

Cardiovascular Diseases

4,904 studies on the registry are indexed under Cardiovascular Diseases; 919 are open to participants now.

This study's enrollment of 24 is below the median of 573 across 1,485 observational studies indexed under Cardiovascular Diseases.

Browse Cardiovascular Diseases studies →

Lead sponsor

Centre Hospitalier Universitaire de Nīmes is the lead sponsor of 587 studies on the registry; 96 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Post-myocardial infarction patients involved in a cardiac rehabilitation program at Nîmes University Hospital, France.

Inclusion criteria

  • Patients must have given written informed consent to participate in the trial
  • Patients must be aged18 to 75 years old
  • It must be less than 6 months after a first episode of myocardial infarction treated medically or by revascularization

Exclusion criteria

Exclusion Criteria:

  • Patients with a disability preventing the performance of a bimanual test or an ergocycle task
  • Patients who are unable to give written informed consent or who have refused to sign the consent form
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
24 participants (actual)
Patient registry
No

Groups and cohorts

  • Diet group

    Patients in this group will receive Evaluative Conditioning favorable to diet. The evaluative conditioning procedure is a learning technique performed on a monitor. It consists of being exposed to the repeated association of an object (conditioned stimulus; in this case, fruit and vegetables) to stimuli with a positive or negative valence (unconditioned stimulus). The total duration of the Evaluative Conditioning is approximately 15 minutes.

    Behavioral: Evaluative conditioning

  • Physical Activity group

    Patients in this group will receive Evaluative Conditioning favorable to Physical Activity. Patients in this group will receive Evaluative Conditioning favorable to diet. The evaluative conditioning procedure is a learning technique performed on a monitor. It consists of being exposed to the repeated association of an object (conditioned stimulus; in this case, Physical Activity) to stimuli with a positive or negative valence (unconditioned stimulus). The total duration of the Evaluative Conditioning is approximately 15 minutes.

    Behavioral: Evaluative conditioning

Interventions

  • BehavioralEvaluative conditioning

    The evaluative conditioning procedure is a learning technique performed on a monitor. It consists of being exposed to the repeated association of an object (conditioned stimulus, in our case, Physical Activity or fruit and vegetables) to stimuli with a positive or negative valence (unconditioned stimulus, US). The total duration of the CE is approximately 15 minutes.

06

What researchers measure

Primary outcomes

  1. Effect of evaluative conditioning on the intensity of physical activity produced by post-myocardial infarction patients involved in a cardiac rehabilitation program. Control group

    The choice of intensity (power setting) on the ergocycle will be measured by controlling it before the Evaluative Conditioning procedure.the ergocycle task consists of pedaling on an indoor bicycle for about 15 minutes, we will only be interested in the intensity data of this task (This task is an integral part of the patients' care at the University Hospital and will be supervised by health professionals - physiotherapist, physical activity teachers, etc.)

    Time frame: Day 0 before completing the Implicit Association Test

  2. Effect of evaluative conditioning on the intensity of physical activity produced by post-myocardial infarction patients involved in a cardiac rehabilitation program. Control group

    The choice of intensity (power setting) on the ergocycle will be measured by controlling it before the Evaluative Conditioning procedure.the ergocycle task consists of pedaling on an indoor bicycle for about 15 minutes, we will only be interested in the intensity data of this task (This task is an integral part of the patients' care at the University Hospital and will be supervised by health professionals - physiotherapist, physical activity teachers, etc.)

    Time frame: Day 0 after completing the Implicit Association Test

  3. Effect of evaluative conditioning on the intensity of physical activity produced by post-myocardial infarction patients involved in a cardiac rehabilitation program. Experimental group

    The choice of intensity (power setting) on the ergocycle will be measured by controlling it before the Evaluative Conditioning procedure.the ergocycle task consists of pedaling on an indoor bicycle for about 15 minutes, we will only be interested in the intensity data of this task (This task is an integral part of the patients' care at the University Hospital and will be supervised by health professionals - physiotherapist, physical activity teachers, etc.)

    Time frame: Day 0 before completing the Implicit Association Test

  4. Effect of evaluative conditioning on the intensity of physical activity produced by post-myocardial infarction patients involved in a cardiac rehabilitation program. Experimental group

    The choice of intensity (power setting) on the ergocycle will be measured by controlling it before the Evaluative Conditioning procedure. Note that the ergocycle task consists of pedaling on an indoor bicycle for about 15 minutes, (this task is an integral part of the patients' care at the University Hospital and will be supervised by health professionals - physiotherapist, physical activity teachers, etc.). Only the intensity data of this task will be recorded

    Time frame: Day 0 after completing the Implicit Association Test

Secondary outcomes

  1. Mediating effect of implicit attitudinal change in the effect of evaluative conditioning on adopted behaviors. Control group

    The change in implicit attitudes will be measured by comparing the Implicit Association Test pretest score (T0) and the Implicit Association Test posttest score (T1).

    Time frame: Time 0, before taking the test

  2. Mediating effect of implicit attitudinal change in the effect of evaluative conditioning on adopted behaviors. Experimental group

    The change in implicit attitudes will be measured by comparing the Implicit Association Test pretest score (T0) and the Implicit Association Test posttest score (T1)

    Time frame: Time 0, before taking the test

  3. Mediating effect of implicit attitudinal change in the effect of evaluative conditioning on adopted behaviors. Control group

    The change in implicit attitudes will be measured by comparing the Implicit Association Test pretest score (T0) and the Implicit Association Test posttest score (T1)

    Time frame: Time 0, after taking the test

  4. Mediating effect of implicit attitudinal change in the effect of evaluative conditioning on adopted behaviors. Experimental group

    The change in implicit attitudes will be measured by comparing the Implicit Association Test pretest score (T0) and the Implicit Association Test posttest score (T1)

    Time frame: Time 0, after taking the test

07

Study locations

1 site
  • Centre Hospitalier Universitaire de Nîmes
    Nîmes, Gard 30900, France
08

References and documents

Publications

  • Hamer M, O'Donovan G, Murphy M. Physical Inactivity and the Economic and Health Burdens Due to Cardiovascular Disease: Exercise as Medicine. Adv Exp Med Biol. 2017;999:3-18. doi: 10.1007/978-981-10-4307-9_1. PubMed 29022254 ↗
  • Clark AM, Hartling L, Vandermeer B, McAlister FA. Meta-analysis: secondary prevention programs for patients with coronary artery disease. Ann Intern Med. 2005 Nov 1;143(9):659-72. doi: 10.7326/0003-4819-143-9-200511010-00010. PubMed 16263889 ↗
  • Birtwistle SB, Jones I, Murphy R, Gee I, Watson PM. "Do what you can with a happy heart": a longitudinal study of patient and family members' lived experiences of physical activity post-myocardial infarction. Disabil Rehabil. 2022 Jul;44(14):3661-3670. doi: 10.1080/09638288.2021.1878560. Epub 2021 Mar 1. PubMed 33646893 ↗
  • Karmali KN, Davies P, Taylor F, Beswick A, Martin N, Ebrahim S. Promoting patient uptake and adherence in cardiac rehabilitation. Cochrane Database Syst Rev. 2014 Jun 25;(6):CD007131. doi: 10.1002/14651858.CD007131.pub3. PubMed 24963623 ↗
  • Antoniewicz F, Brand R. Learning to Like Exercising: Evaluative Conditioning Changes Automatic Evaluations of Exercising and Influences Subsequent Exercising Behavior. J Sport Exerc Psychol. 2016 Apr;38(2):138-48. doi: 10.1123/jsep.2015-0125. Epub 2016 Mar 15. PubMed 27385674 ↗
  • Chevance G, Bernard P, Chamberland PE, Rebar A. The association between implicit attitudes toward physical activity and physical activity behaviour: a systematic review and correlational meta-analysis. Health Psychol Rev. 2019 Sep;13(3):248-276. doi: 10.1080/17437199.2019.1618726. Epub 2019 Jun 12. PubMed 31117901 ↗
  • Rebar AL, Dimmock JA, Jackson B, Rhodes RE, Kates A, Starling J, Vandelanotte C. A systematic review of the effects of non-conscious regulatory processes in physical activity. Health Psychol Rev. 2016 Dec;10(4):395-407. doi: 10.1080/17437199.2016.1183505. Epub 2016 May 20. PubMed 27118430 ↗
  • Hofmann W, De Houwer J, Perugini M, Baeyens F, Crombez G. Evaluative conditioning in humans: a meta-analysis. Psychol Bull. 2010 May;136(3):390-421. doi: 10.1037/a0018916. PubMed 20438144 ↗
  • Rogerson MC, Murphy BM, Bird S, Morris T. "I don't have the heart": a qualitative study of barriers to and facilitators of physical activity for people with coronary heart disease and depressive symptoms. Int J Behav Nutr Phys Act. 2012 Nov 30;9:140. doi: 10.1186/1479-5868-9-140. PubMed 23194091 ↗
  • Rhodes RE, Janssen I, Bredin SSD, Warburton DER, Bauman A. Physical activity: Health impact, prevalence, correlates and interventions. Psychol Health. 2017 Aug;32(8):942-975. doi: 10.1080/08870446.2017.1325486. Epub 2017 May 30. PubMed 28554222 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 10, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06795802
Lead sponsor
Centre Hospitalier Universitaire de Nīmes
Responsible party
Sponsor
First posted
Jan 28, 2025
Start date
Apr 26, 2023
Primary completion
Jun 25, 2025
Completion
Jun 25, 2025
Last update
Dec 10, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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