An observational study in Ultrasonography, sponsored by Charles University, Czech Republic. Not yet recruiting at 1 site in Czech Republic. Open to participants aged 10 Years to 14 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-01-24.
Sponsored by Charles University, Czech Republic · Observational
The goal of this observational study is to evaluate the validity and reliability of ultrasound echo intensity (EI) as a diagnostic tool for assessing muscle quality in children aged 10-14 years, including normal-weight, obese, and trained young athletes. The main questions it aims to answer are:
Can EI reliably and accurately measure muscle quality in children when validated against gold-standard techniques like DXA and isokinetic dynamometry? What are the age-, sex-, and fitness-specific benchmarks for EI to differentiate between normal and pathological muscle quality?
Charles University, Czech Republic is the lead sponsor of 220 studies on the registry; 76 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Sixty boys and sixty girls aged 10-14 years, evenly distributed as follows: normal-weight children, trained young athletes (≥3 training sessions per week), and obese children according to BMI
Exclusion Criteria:
Echo intensity of the vastus lateralis (VL) and rectus femoris (RF) muscles
Echo intensity will be measured by greyscale analysis derivered from ultrasound imaging.
Time frame: Through study completion, an average of 1 year
Skeletal Muscle Mass
Measured using DXA (Horizon DXA platform, Hologic)
Time frame: Through study completion, an average of 1 year
Muscle Strength
Assessed via isokinetic and isometric knee extensor strength using a Humac Norm isokinetic dynamometer
Time frame: Through study completion, an average of 1 year
Plan to share: No
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Charles University, Czech Republic