An observational study in Thoracic Aortic Aneurysm, Thoracic Aortic Dissection and Thoracic Aorta Abnormality, sponsored by University of Calgary. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-06-29.
Sponsored by University of Calgary · Observational
Though the application of thoracic endovascular aortic repair (TEVAR) for treatment of aortic pathology is expanding, there remains a gap in the literature examining how intraoperative "reduction or elimination of aortic impulse" (REAI) techniques, in particular the use of right atrial occlusion, may impact patient important clinical outcomes. This study aims to provide prospective data from a large cohort of TEVAR patients to explore clinical outcomes following TEVAR procedures and, specifically, whether right atrial occlusion has significant impact on clinical outcomes, as compared to other REAI techniques. The results from this study may inform future perioperative TEVAR practices and improve TEVAR patient outcomes.
131 studies on the registry are indexed under Aortic Aneurysm, Thoracic; 33 are open to participants now.
This study's planned enrollment of 100 is below the median of 154 across 65 observational studies indexed under Aortic Aneurysm, Thoracic.
Browse Aortic Aneurysm, Thoracic studies →University of Calgary is the lead sponsor of 703 studies on the registry; 196 are open to participants now.
Of its 10 completed or terminated interventional studies of FDA-regulated products, 2 (20%) have results posted.
Counted across the registry records on this site, refreshed daily.
All patients undergoing emergency or elective thoracic endovascular aortic repair at the Peter Lougheed Centre, Calgary, Alberta
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Thoracic endovascular aortic repair with right atrial balloon occlusion for reduction or elimination of aortic impulse
Procedure: Right atrial balloon occlusion
Thoracic endovascular aortic repair not using right atrial balloon occlusion for reduction or elimination of aortic impulse
Procedure: Non right atrial balloon occlusion
Thoracic endovascular aortic repair with right atrial balloon occlusion for reduction or elimination of aortic impulse and stent graft deployment in landing zones 0-3
Thoracic endovascular aortic repair not using right atrial balloon occlusion for reduction or elimination of aortic impulse and stent graft deployment in landing zones 0-3
Endoleak occurrence up to hospital discharge
Endoleak occurrence prior to hospital discharge
Time frame: end of surgery to hospital discharge up to 10 days)
Endoleak occurrence to one-year post-surgery
Endoleak occurrence within one-year of surgery
Time frame: end of surgery to one-year post-surgery
Perioperative mortality to 30 days post-surgery
30-day perioperative mortality
Time frame: post-surgery to 30 days post-surgery
All-cause mortality to one-year post-surgery
One-year all-cause mortality
Time frame: post-surgery to one-year post-surgery
Complications: massive hemorrhage
Occurrence of massive hemorrhage
Time frame: within 30 days post-surgery and at 1 year
Complications: cerebrovascular
Occurrence of cerebrovascular accident/transient ischemic attack
Time frame: within 30 days post-surgery and at 1 year
Complications: spinal cord ischemia
Occurrence of spinal cord ischemia
Time frame: within 30 days post-surgery and at 1 year
Complications: iliofemoral access
Occurrence of iliofemoral access complications (bleeding/infection/thrombosis)
Time frame: within 30 days post-surgery and at 1 year
Complications: retrograde dissection
Occurrence of retrograde dissection
Time frame: within 30 days post-surgery and at 1 year
Complications: prolonged ventilation
Occurrence of prolonged ventilation for more than 24 hours
Time frame: within 30 days post-surgery and at 1 year
Complications: acute kidney injury
Occurrence of acute kidney injury
Time frame: within 30 days post-surgery and at 1 year
Complications: acute kidney injury with renal replacement therapy
Occurrence of acute kidney injury requiring renal replacement therapy
Time frame: within 30 days post-surgery and at 1 year
Complications: cardiovascular events
Occurrence of cardiovascular events (myocardial injury after non-cardiac surgery/cardiac arrest/myocardial infarction)
Time frame: within 30 days post-surgery and at 1 year
No study locations are listed for this record.
Start is estimated for Sep 2025; primary completion for Jan 2029, 40 months later.
Of 42 observational studies under Aortic Aneurysm, Thoracic, half reached primary completion within 83 months of starting (the median), counting those still running; a quarter within 25 and three quarters within 98. This study's planned 40 months is below that.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Jun 2025. You cannot join it, but the record below documents what was studied.
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