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Active, not recruitingNCT06785935Updated Jan 21, 2025

Comparison Between 2 Treatment Modalities of Trigger Finger: Ultrasound-guided Percutaneous Release of A1 Pulley by a Needle Knife Versus Ultrasound-guided Corticosteroid Injection in the Treatment of Trigger Finger

An interventional study of Needle knife and Corticosteroid: Betamethasone in Trigger Finger, sponsored by Mansoura University Hospital. Active, not recruiting at 1 site in Egypt. Per ClinicalTrials.gov, last updated 2025-01-21.

Sponsored by Mansoura University Hospital · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by May 2025, 1 year 6 months ago, but the record still lists the study as active, not recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Sex
All
01

Study summary

Trigger finger is a common cause of hand disability and pain in the general population. It is a pathologic condition of the digital pulleys and flexor tendons. Although the pathogenesis is incompletely clear and multifactorial, the most common cause of the trigger finger is the thickened flexor tendon and/or thickened first annular (A1) pulley located at the metacarpophalangeal joint. Currently, ultrasound is considered an effective and valuable tool for assessing the trigger finger, providing static and dynamic evaluations of this condition and a comparison with the adjacent normal digits. Recently, it has been reported that ultrasound-guided percutaneous A1 pulley precise release using a needle knife has received increasing attention in the clinical treatment of trigger fingers and achieved good results. To our knowledge, this is the first clinical study comparing the efficacy and safety of ultrasonic-guided percutaneous A1 pulley release with a needle knife and the ultrasonic-guided steroid injection in treating trigger fingers.

02

Conditions studied

  • Trigger Finger
03

In context

Trigger Finger Disorder

93 studies on the registry are indexed under Trigger Finger Disorder; 22 are open to participants now.

This study's enrollment of 40 is below the median of 66 across 75 interventional studies indexed under Trigger Finger Disorder.

Browse Trigger Finger Disorder studies →

Lead sponsor

Mansoura University Hospital is the lead sponsor of 50 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Idiopathic trigger finger
  • Trigger finger at the level of A1 pulley
  • Trigger finger of Green's grades II or III

Exclusion criteria

Exclusion Criteria:

  • Patients with secondary causes of trigger fingers like diabetes mellitus, rheumatoid arthritis, gout, hypothyroidism, amyloidosis, and sarcoidosis.
  • Patients with a previous history of first annular pulley release or injection.
  • Patients with trigger fingers of Green's grade I and IV.
  • Patients with trigger fingers at any level other than the A1 pulley.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
40 participants (actual)

Study arms

  • Active comparator
    Patients undergoing ultrasonography-guided percutaneous A1 pulley release using a needle knife

    Device: Needle knife

  • Active comparator
    Patients undergoing ultrasonography-guided corticosteroid injection under the A1 pulley

    Drug: Corticosteroid: Betamethasone

Interventions

  • DeviceNeedle knife

    ultrasonography-guided percutaneous A1 pulley release using a needle knife

  • ultrasonography-guided corticosteroid injection under the A1 pulley

06

What researchers measure

Primary outcomes

  1. Pain intensity using the visual analog scale (VAS) scoring system

    Time frame: Before the procedure as well as after one week, one month, and three months

  2. Functional ability according to the standard quick disabilities of the arm, shoulder, and hand score (Q DASH) questionnaire

    Time frame: Before the procedure as well as after one week, one month, and three months

  3. Recurrence: The grade of trigger finger according to Green's classification

    Time frame: Before the procedure as well as after one week, one month, and three months

  4. Complications such as inflammation, infection, scarring, wound healing problems, and sensory changes

    Time frame: After one week of the procedure

07

Study locations

1 site
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 21, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06785935
Lead sponsor
Mansoura University Hospital
Responsible party
Nouran Khalid Ibrahim Sallam (Resident of Rheumatology, rehabilitation, and physical medicine department at Mansoura University Hospitals, Mansoura University Hospital) — Principal investigator
First posted
Jan 21, 2025
Start date
Nov 11, 2024
Primary completion
May 2025 (estimated)
Completion
Dec 2025 (estimated)
Last update
Jan 21, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Dec 2024. You cannot join it, but the record below documents what was studied.

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Discussion

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Studies of the drug tested here: Betamethasone

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