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Active, not recruitingNCT06761599Updated Jan 7, 2025

Frequency of Pulmonary Toxicity in Patients Treated for Hodgkin Lymphoma

An observational study in Hodgkin Lymphoma, sponsored by Superior University. Active, not recruiting at 1 site in Pakistan. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-01-07.

Sponsored by Superior University · Observational

Study type
Observational
Model
Case-control
Time perspective
Retrospective
Enrollment
214
Ages
18 Years and older
Sex
All
01

Study summary

Pulmonary toxicity during Hodgkin lymphoma treatment is significant for a variety of reasons, ranging from clinical care to therapeutic innovation and patient outcomes.

Read the detailed description

Understanding chemotherapy-induced pulmonary issues, particularly bleomycin-induced toxicity, might enhance treatment efficacy, side effects, and quality of life for Hodgkin lymphoma patients. For Hodgkin lymphoma chemotherapy patients with pulmonary difficulties, which result in significant patient morbidity and mortality, early detection, proactive surveillance, and rapid management are required. Identifying the prevalence, risk factors, and clinical signs of pulmonary toxicity helps clinicians stratify treatment.

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Conditions studied

  • Hodgkin Lymphoma
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In context

Lymphoma

5,578 studies on the registry are indexed under Lymphoma; 825 are open to participants now.

This study's enrollment of 214 is above the median of 136 across 625 observational studies indexed under Lymphoma.

Browse Lymphoma studies →

Lead sponsor

Superior University is the lead sponsor of 242 studies on the registry; 24 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

to check the Frequency of Pulmonary Toxicity in Patients Treated for Hodgkin Lymphoma

Inclusion criteria

  • Patients diagnosed with Hodgkin lymphoma (HL) receiving treatment.
  • Patients of all ages and both genders.
  • Patients with histologically confirmed HL, as per the WHO 2016 classification.
  • Patients who have undergone pulmonary function testing and assessment at specified time points during their treatment course.
  • Patients with complete medical records documenting treatment regimens, including chemotherapy and radiotherapy details.

Exclusion criteria

Exclusion Criteria:

  • Patients with a diagnosis of another malignancy.
  • Patients with incomplete medical records or missing data on treatment regimens and pulmonary function assessments.
  • Patients with a history of significant pulmonary comorbidities, such as chronic obstructive pulmonary disease (COPD), interstitial lung disease, or pulmonary fibrosis, before HL diagnosis.
  • Patients who are unable to complete pulmonary function tests.
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Study design

Observational model
Case-control
Time perspective
Retrospective
Enrollment
214 participants (actual)
Patient registry
No

Interventions

  • Diagnostic testgroup 1

    To determine treatment-induced pulmonary toxicity prevalence and risk factors in Hodgkin lymphoma patients during chemotherapy or radiation therapy.

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What researchers measure

Primary outcomes

  1. high-resolution computed tomography

    An HRCT (high-resolution computed tomography) scan is a type of CT scan healthcare providers use to get detailed images of your lungs. Providers most commonly use it to diagnose and monitor interstitial lung diseases and conditions that affect your small airways and alveoli (air sacs).

    Time frame: 12 Months

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Study locations

1 site
  • Shaukat Khanum Memorial Cancer Hospital and Research Centre, 5-B, Sector A2, Phase 5, Hayatabad
    Peshawar, Khyber Pakhtunkhwa, Pakistan
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 7, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06761599
Lead sponsor
Superior University
Responsible party
Muhammad Naveed Babur (Principal Investigator, Superior University) — Principal investigator
First posted
Jan 7, 2025
Start date
Feb 18, 2024
Primary completion
Jul 15, 2024
Completion
Mar 1, 2025 (estimated)
Last update
Jan 7, 2025

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.

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