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Active, not recruitingNCT06709989DAISY-ExpoUpdated Mar 9, 2026

Chemical and Microbiological Exposure of Women on Dairy Cattle Farms

An observational study in Occupational Exposure to Chemicals, sponsored by Institut National de la Santé Et de la Recherche Médicale, France. Active, not recruiting at 1 site in France. Open to female participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-09.

Sponsored by Institut National de la Santé Et de la Recherche Médicale, France · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
80
Ages
18 Years and older
Sex
Female
01

Study summary

Although professionals working on dairy cattle farms come into contact with a wide range of chemicals and microbiological agents, little is known about this possible exposure, which occurs a priori via inhalation and skin contact.

The aim of this research is to gain a better understanding of this chemical and microbiological exposure, and this research focuses in particular on professional women working on dairy cattle farms , who may be in charge of specific activities not commonly carried out by professional men.

Exposure to pesticides, antiparasitic products and disinfectants will be the first substances to be investigated, followed by other chemical or particulate compounds present in everyday and professional environments. Exposure to these compounds will be measured by their presence in the urine, feces (if possible) and hair of around 60 participating women, as well as in bovine tuft/head hair and, if possible, air samples taken in milking buildings.

02

Conditions studied

  • Occupational Exposure to Chemicals

Keywords

  • farmer
  • women
  • occupational exposure
  • chemicals
  • pesticides
  • biocides
03

In context

Lead sponsor

Institut National de la Santé Et de la Recherche Médicale, France is the lead sponsor of 375 studies on the registry; 82 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Adult women working on dairy cattle farms in West area of France

Inclusion criteria

  • Adult woman working on a dairy cattle farm in the "Grand Ouest" region of France
  • Woman who speaks and understands French

Exclusion criteria

Exclusion Criteria:

  • working less than 20h/week in dairy farms
  • Woman under legal protection
  • unsigned consent form
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
80 participants (estimated)
Patient registry
No
Biospecimen retention
Samples without dna
06

What researchers measure

Primary outcomes

  1. Exposure to chemicals of women working on dairy farms

    Concentrations of pesticide molecules, biocides, disinfectants and microbiological agents, measured in * urines of professional women working on dairy farms, * the hair of professional women working on dairy farms, * faeces of professional women from dairy farms, * tuft/head hair from females in the herd on farms where female professionals work, * environmental samples of pesticide molecules (PPPs, pesticides), biocides, disinfectants and microbiological agents.

    Time frame: At inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling)

Secondary outcomes

  1. Exposure to other chemicals

    Concentrations measured in urine, hair, feces, toupillon/head hair and environmental samples from the farm of other chemical compounds present in the participants' professional uses and environments.

    Time frame: At inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling)

07

Study locations

1 site
  • UMR1085 Irset
    Rennes, 35000, France
08

References and documents

Individual participant data

Plan to share: No — No or required a additional/new ethic authorization

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 9, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06709989
Lead sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Collaborators
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Ecole des Hautes Etudes en Santé Publique
Responsible party
Sponsor
First posted
Nov 29, 2024
Start date
Jan 3, 2025
Primary completion
Jan 2028 (estimated)
Completion
Jan 2028 (estimated)
Last update
Mar 9, 2026

Study contacts

Cecile Chevrier
principal investigator · Inserm UMR1085 Irset

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.

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