An observational study in Tuberculosis, sponsored by Sohag University. Not yet recruiting at 1 site in Egypt. Open to participants aged 16 Years to 60 Years. Per ClinicalTrials.gov, last updated 2024-11-29.
Sponsored by Sohag University · Observational
Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is one of the top 10 causes of mortality worldwide. It is estimated that in 2017, 10 million people were infected with TB, and 1.6 million died from the disease, including 0.3 million people with human immunodeficiency virus (HIV) infection . TB remains the primary killer of HIV-positive individuals. TB incidence is falling at about 2% per year . Airborne transmission of M. tuberculosis typically causes TB infection in both immunocompetent and immunocompromised hosts and the disease is symptomatic and contagious .
TB and HIV infections are strictly linked together. TB is the most common opportunistic infection and causes high morbidity rate among people living with HIV. Because of the decrease in cell-mediated immunity, HIV alters the pathogenesis of TB, thereby expressively increasing the risk of TB in HIV-positive patients and eventually leading to more severe complications and forms of TB.
1,417 studies on the registry are indexed under Tuberculosis; 208 are open to participants now.
This study's planned enrollment of 200 is below the median of 250 across 421 observational studies indexed under Tuberculosis.
Browse Tuberculosis studies →Sohag University is the lead sponsor of 1,183 studies on the registry; 612 are open to participants now.
Counted across the registry records on this site, refreshed daily.
This prospective study will be conducted on 100-200 patients with pulmonary and extra pulmonary TB attending Sohag University Hospital during the period from September 2024 to August 2025
Exclusion Criteria:
estimation of antigens and antibodies to diagnose HIV
staining sputum from patients with HIV to detect tubercle bacilli
spenciem will be inoculated on LJ media and kept for 2-8 weeks, to see small white colonies
to see the pattern of antibiotic resistance of tubercle bacilli
The Prevalance of tubercuolsis in immunocompetent patients suffereing from chronic chest problems
Patients suffering from chronic chest problems will be screened for presence of TB bacilli using chest X-ray, sputum smear, culture on LJ media, detection of DNA of TB bacilli using PCR
Time frame: December 2024- June 2025
The prevalence of tuberculosis in HIV patients
Detection of tubercle bacilli in HIV positive patients , these patients will be screened for presence of TB bacilli using chest X-ray, sputum smear, culture on LJ media, detection of DNA of TB bacilli using PCR
Time frame: December 2024- June 2025
Plan to share: No
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This study is not yet recruiting, as verified in Nov 2024. You cannot join it, but the record below documents what was studied.
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Sohag University